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01-03-2018 | Clinical Investigation

Semi-automated software to measure luminal and stromal areas of choroid in optical coherence tomographic images

Authors: Shozo Sonoda, Taiji Sakamoto, Naoko Kakiuchi, Hideki Shiihara, Tomonori Sakoguchi, Masatoshi Tomita, Takehiro Yamashita, Eisuke Uchino

Published in: Japanese Journal of Ophthalmology | Issue 2/2018

Abstract

Purpose

To determine the capabilities of “EyeGround” software in measuring the choroidal cross sectional areas in optical coherence tomographic (OCT) images.

Study design

Cross sectional, prospective study.

Methods

The cross-sectional area of the subfoveal choroid within a 1500 µm diameter circle centered on the fovea was measured both with and without using the EyeGround software in the OCT images. The differences between the evaluation times and the results of the measurements were compared. The inter-rater, intra-rater, inter-method agreements were determined.

Results

Fifty-one eyes of 51 healthy subjects were studied: 24 men and 27 women with an average age of 35.0 ± 8.8 years. The time for analyzing a single image was significantly shorter with the software at 3.2±1.1 min than without the software at 12.1±5.1 min (P <0.001). The inter-method correlation efficient for the measurements of the whole choroid was high [0.989, 95% CI (0.981-0.994)]. With the software, the inter-rater correlation efficient was significantly high [0.997, 95% CI (0.995-0.999)], and the intra-rater correlation efficient was also significantly high [0.999, 95% CI (0.999-1.0)].

Conclusion

The EyeGround software can measure the choroidal area in the OCT cross sectional images with good reproducibility and in a significantly shorter times. It can be a valuable tool for analyzing the choroid.

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Title: Semi-automated software to measure luminal and stromal areas of choroid in optical coherence tomographic images
Authors: Shozo Sonoda
Taiji Sakamoto
Naoko Kakiuchi
Hideki Shiihara
Tomonori Sakoguchi
Masatoshi Tomita
Takehiro Yamashita
Eisuke Uchino
Publication date: 01-03-2018
Publisher: Springer Japan
Published in: Japanese Journal of Ophthalmology / Issue 2/2018
Print ISSN: 0021-5155
Electronic ISSN: 1613-2246
DOI: https://doi.org/10.1007/s10384-017-0558-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Semi-automated software to measure luminal and stromal areas of choroid in optical coherence tomographic images

Abstract

Purpose

Study design

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Study design

Methods

Results

Conclusion

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