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Diseases of the Colon & Rectum
Published in: Diseases of the Colon & Rectum 7/2008

01-07-2008 | Original Contribution

The Impact of 18-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography on the Staging and Management of Primary Rectal Cancer

Authors: K. Davey, F.R.A.C.S., A. G. Heriot, M.D., F.R.C.S., F.R.A.C.S., J. Mackay, F.R.A.C.S., E. Drummond, M.Sc., A. Hogg, Ph.D., S. Ngan, F.R.A.N.Z.C.R., A. D. Milner, Ph.D., R. J. Hicks, M.D., F.R.A.C.P.

Published in: Diseases of the Colon & Rectum | Issue 7/2008

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Abstract

Purpose

18-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) has a role in recurrent colorectal cancer. This study was designed to assess the impact of PET-CT on management of primary rectal cancer.

Methods

Eighty-three patients with rectal cancer underwent PET-CT scan between 2002 and 2005. Referring physicians prospectively recorded stage and management plan after conventional imaging before PET-CT scan, which were compared to subsequent stage and management after PET-CT.

Results

Staging PET-CT caused a change in stage from conventional imaging in 26 patients (31 percent). Twelve (14 percent) were upstaged (7 change in N stage; 4 change in M stage; 1 change in N and M stage), and 14 (17 percent) were downstaged (10 change in N stage; 3 change in M stage; 1 change in N and M stage). PET-CT scan altered management intent in seven patients (8 percent) (curative to palliative 6 patients; palliative to curative 1 patient). Management was altered in ten patients (12 percent). There was no difference in impact with respect to tumor height.

Conclusions

PET-CT scan impacts the management of patients with primary rectal cancer and influences staging/therapy in a third of patients and should be a component of rectal cancer workup.
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Metadata
Title
The Impact of 18-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography on the Staging and Management of Primary Rectal Cancer
Authors
K. Davey, F.R.A.C.S.
A. G. Heriot, M.D., F.R.C.S., F.R.A.C.S.
J. Mackay, F.R.A.C.S.
E. Drummond, M.Sc.
A. Hogg, Ph.D.
S. Ngan, F.R.A.N.Z.C.R.
A. D. Milner, Ph.D.
R. J. Hicks, M.D., F.R.A.C.P.
Publication date
01-07-2008
Publisher
Springer-Verlag
Published in
Diseases of the Colon & Rectum / Issue 7/2008
Print ISSN: 0012-3706
Electronic ISSN: 1530-0358
DOI
https://doi.org/10.1007/s10350-008-9244-1

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