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Clinical Autonomic Research
Published in: Clinical Autonomic Research 1/2020

01-02-2020 | Affective Disorder | Short Communication

ST-segment changes during tilt table testing for postural tachycardia syndrome: correlation with exercise stress test results

Authors: Ramya Vajapey, Erika Hutt Centeno, Erik H. Van Iterson, Haitham M. Ahmed, Kenneth A. Mayuga

Published in: Clinical Autonomic Research | Issue 1/2020

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Abstract

Background

Prior studies have reported ECG (Electrocardiogram) changes during tilt table testing (TTT), specifically during repolarization with ST-segment and T-wave changes. The correlation with ischemic evaluation remains unclear. The purpose of this study was to analyze the prevalence of ST-segment changes during TTT in a young, otherwise healthy population of patients with postural tachycardia syndrome (POTS), and correlate them with exercise stress test results.

Methods

Two hundred and fifty-five patients with POTS who underwent TTT and an exercise treadmill test (ETT) were analyzed.

Results

Forty-five had ST-segment changes/depressions during TTT (91% female, average age 36 years). Of the 45, three had ST-segment depression during ETT; all three had negative exercise stress echocardiograms (ESEs). Two others had ST-segment depressions on ETT (but not TTT), with negative ESEs.

Conclusion

In a cohort of young, female, otherwise healthy patients with POTS, ST-segment changes occurred in a significant portion (18%) of patients during TTT. When evaluated with exercise stress testing, these patients had no evidence of underlying ischemia on ETT or ESE.
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Metadata
Title
ST-segment changes during tilt table testing for postural tachycardia syndrome: correlation with exercise stress test results
Authors
Ramya Vajapey
Erika Hutt Centeno
Erik H. Van Iterson
Haitham M. Ahmed
Kenneth A. Mayuga
Publication date
01-02-2020
Publisher
Springer Berlin Heidelberg
Published in
Clinical Autonomic Research / Issue 1/2020
Print ISSN: 0959-9851
Electronic ISSN: 1619-1560
DOI
https://doi.org/10.1007/s10286-019-00633-9

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