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Clinical Autonomic Research
Published in: Clinical Autonomic Research 3/2018

01-06-2018 | Review

Roles of catechol neurochemistry in autonomic function testing

Authors: David S. Goldstein, William P. Cheshire

Published in: Clinical Autonomic Research | Issue 3/2018

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Abstract

Catechols are a class of compounds that contain adjacent hydroxyl groups on a benzene ring. Endogenous catechols in human plasma include the catecholamines norepinephrine, epinephrine (adrenaline), and dopamine; the catecholamine precursor DOPA, 3,4-dihydroxyphenylglycol (DHPG), which is the main neuronal metabolite of norepinephrine; and 3,4-dihydroxyphenylacetic acid (DOPAC), which is the main neuronal metabolite of dopamine. In the diagnostic evaluation of patients with known or suspected dysautonomias, measurement of plasma catechols is rarely diagnostic but often is informative. This review summarizes the roles of clinical catechol neurochemistry in autonomic function testing.
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Metadata
Title
Roles of catechol neurochemistry in autonomic function testing
Authors
David S. Goldstein
William P. Cheshire
Publication date
01-06-2018
Publisher
Springer Berlin Heidelberg
Published in
Clinical Autonomic Research / Issue 3/2018
Print ISSN: 0959-9851
Electronic ISSN: 1619-1560
DOI
https://doi.org/10.1007/s10286-018-0528-9

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