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Clinical Autonomic Research
Published in: Clinical Autonomic Research 1/2017

Open Access 01-07-2017 | Case Vignette

Polypharmacy: droxidopa to treat neurogenic orthostatic hypotension in a patient with Parkinson disease and type 2 diabetes mellitus

Authors: Steven Vernino, Daniel Claassen

Published in: Clinical Autonomic Research | Special Issue 1/2017

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Excerpt

In patients with polypharmacy, what medications may limit the potential use of droxidopa? …
Literature
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Fanciulli A, Gobel G, Ndayisaba JP, Granata R, Duerr S, Strano S, Colosimo C, Poewe W, Pontieri FE, Wenning GK (2016) Supine hypertension in Parkinson’s disease and multiple system atrophy. Clin Auton Res 26:97–105
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McClellan KJ, Wiseman LR, Wilde MI (1998) Midodrine. A review of its therapeutic use in the management of orthostatic hypotension. Drugs Aging 12:76–86CrossRefPubMed
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Okamoto LE, Shibao C, Gamboa A, Choi L, Diedrich A, Raj SR, Black BK, Robertson D, Biaggioni I (2012) Synergistic effect of norepinephrine transporter blockade and alpha-2 antagonism on blood pressure in autonomic failure. Hypertension 59:650–656CrossRefPubMedPubMedCentral
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Smith W, Wan H, Much D, Robinson AG, Martin P (2016) Clinical benefit of midodrine hydrochloride in symptomatic orthostatic hypotension: a phase 4, double-blind, placebo-controlled, randomized, tilt-table study. Clin Auton Res 26:269–277
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Umehara T, Matsuno H, Toyoda C, Oka H (2016) Clinical characteristics of supine hypertension in de novo Parkinson disease. Clin Auton Res 26:15–21
Metadata
Title
Polypharmacy: droxidopa to treat neurogenic orthostatic hypotension in a patient with Parkinson disease and type 2 diabetes mellitus
Authors
Steven Vernino
Daniel Claassen
Publication date
01-07-2017
Publisher
Springer Berlin Heidelberg
Published in
Clinical Autonomic Research / Issue Special Issue 1/2017
Print ISSN: 0959-9851
Electronic ISSN: 1619-1560
DOI
https://doi.org/10.1007/s10286-017-0435-5

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