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Clinical Autonomic Research
Published in: Clinical Autonomic Research 6/2015

01-12-2015 | Research Article

Skin sympathetic function in complex regional pain syndrome type 1

Authors: Anupama Poudel, Masato Asahina, Yoshikatsu Fujinuma, Yoshitaka Yamanaka, Akira Katagiri, Nobuyuki Araki, Shigeki Hirano, Satoshi Kuwabara

Published in: Clinical Autonomic Research | Issue 6/2015

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Abstract

Purpose

Cutaneous sympathetic pathophysiology in complex regional pain syndrome type 1 (CRPS-1) is not yet completely understood. To evaluate cutaneous sympathetic dysfunction in CRPS-1, we evaluated sympathetic sweat response (SSwR) and skin vasomotor reflex (SkVR) in CRPS-1 patients.

Methods

We studied 10 CRPS-1 patients (age 41 ± 13 years; 5 females and 5 males; disease duration 20 ± 22 months) and 10 healthy subjects (age 44 ± 13 years; 3 females and 7 males). SkVRs and SSwRs to several sympathetic activating procedures were recorded on the palms of the CRPS-1 patients (affected side) and controls (right side).

Results

There were no significant differences in the baselines of sweat output and skin blood flow between the CRPS-1 and control groups. SSwR and SkVR amplitudes were significantly lower in the CRPS-1 group than in the control group. There was no significant correlation between disease duration and SSwR or SkVR amplitudes among the patients.

Conclusions

The reduced SSwRs and SkVRs in the affected limb of our CRPS-1 patients may reflect underlying damage to the sympathetic postganglionic fibres.
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Metadata
Title
Skin sympathetic function in complex regional pain syndrome type 1
Authors
Anupama Poudel
Masato Asahina
Yoshikatsu Fujinuma
Yoshitaka Yamanaka
Akira Katagiri
Nobuyuki Araki
Shigeki Hirano
Satoshi Kuwabara
Publication date
01-12-2015
Publisher
Springer Berlin Heidelberg
Published in
Clinical Autonomic Research / Issue 6/2015
Print ISSN: 0959-9851
Electronic ISSN: 1619-1560
DOI
https://doi.org/10.1007/s10286-015-0314-x

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