Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Clinical Autonomic Research
Published in: Clinical Autonomic Research 4/2008

01-08-2008 | AUTONOMIC NEWS

Research highlights from the literature

Author: Prof. Vaughan G. Macefield, Ph.D.

Published in: Clinical Autonomic Research | Issue 4/2008

Login to get access

Abstract

Deep brain stimulation of the subthalamic nucleus has been used successfully to treat tremor in Parkinson’s disease, and more recently stimulation within the subgenual anterior cingulate has been used to treat intractable depression. While there have been some reports of deep brain stimulation affecting the autonomic nervous system, its use in alleviating the debilitating pain of headaches has a firm neurobiological basis. Stimulation within the posterior inferior hypothalamus is believed to act by modulation of pain transmission within the trigeminal nucleus.
Literature
1.
Cordella R, Carella F, Leone M, Franzini A, Broggi G, Bussone G, Albanese A (2007) Spontaneous neuronal activity of the posterior hypothalamus in trigeminal autonomic cephalgia. Neurol Sci 28:93–95PubMedCrossRef
2.
3.
Diamond A, Kenney C, Almaguer M, Jankovic J (2007) Hyperhidrosis due to deep brain stimulation in a patient with essential tremor. Case report. J Neurosurg 107:1036–1038PubMedCrossRef
4.
Erola T, Haapaniemi T, Heikkinen E, Huikuri H, Myllyä V (2006) Subthalamic nuleus deep brain stimulation does not alter long-term heart rate variability in Parkinson’s disease. Clin Auton Res 16:286–288PubMedCrossRef
5.
Goadsby PJ, Cittadini E, Burns B, Cohen AS (2008) Trigeminal autonomic cephalalgias: diagnostic and therapeutic developments. Curr Opin Neurol 21:323–330PubMedCrossRef
6.
Green AL, Wang S, Owen SL, XIe K, Bittar RG, Stein JF, Paterson DJ, Aziz TZ (2006) Stimulating the human midbrain to reveal the link between pain and blood pressure. Pain 124:349–359PubMedCrossRef
7.
Irimia P, Cittadini E, Paemeleire K, Cohen AS, Goadsby PJ (2008) Unilateral photophobia or phonophobia in migraine compared with trigeminal autonomic cephalalgias. Cephalalgia 28:626–630PubMedCrossRef
8.
Johansen-Berg H, Gutman DA, Behrens TE, Matthews PM, Rushworth MF, Katz E, Lozano AM, Mayberg HS (2008) Anatomical connectivity of the subgenual cingulate region targeted with deep brain stimulation for treatment-resistant depression. Cereb Cortex 18:1374–1383PubMedCrossRef
9.
10.
Leone M, Proietti Cecchini A, Franzini A, Broggi G, Cortelli P, Montagna P, May A, Juergens T, Cordella R, Carella F, Bussone G (2008) Lessons from 8 years’ experience of hypothalamic stimulation in cluster headache. Cephalalgia 28:787–797PubMedCrossRef
11.
Ludwig J, Remien P, Guballa C, Binder A, Binder S, Schattschneider J, Herzog J, Volkmann J, Deuschl G, Wasner G, Baron R (2007) Effects of subthalamic nucleus stimulation and levodopa on the autonomic nervous system in Parkinson’s disease. J Neurol Neurosurg Psychiatry 78:742–745PubMedCrossRef
12.
May A, Leone M, Boecker H, Sprenger T, Juergens T, Bussone G, Tolle TR (2006) Hypothalamic deep brain stimulation in positron emission tomography. J Neurosci 26:3589–3593PubMedCrossRef
13.
McNeely HE, Mayberg HS, Lozano AM, Kennedy SH (2008) Neuropsychological impact of Cg25 deep brain stimulation for treatment-resistant depression: preliminary results over 12 months. J Nerv Ment Dis 196:405–410PubMedCrossRef
14.
Nordin M, Fagius J, Waldenlind E (1997) Sympathetic vasoconstrictor outflow to extremity muscles in cluster headache. Recordings during spontaneous and nitroglycerin-induced attacks. Headache 37:358–367CrossRef
15.
Owen SL, Green AL, Davies P, Stein JF, Aziz TZ, Behrens T, Voets NL, Johansen-Berg H (2007) Connectivity of an effective hypothalamic surgical target for cluster headache. J Clin Neurosci 14:955–960PubMedCrossRef
16.
Shapira NA, Okun MS, Wint D, Foote KD, Byars JA, Bowers D, Springer US, Lang PJ, Greenberg BD, Haber SN, Goodman WK (2006) Panic and fear induced by deep brain stimulation. J Neurol Neurosurg Psychiat 77:410–412PubMedCrossRef
17.
Stemper B, Beric A, Welsch G, Haendl T, Sterio D, Hilz MJ (2006) Deep brain stimulation improves orthostatic regulation of patients with Parkinson disease. Neurology 67:1781–1785PubMedCrossRef
Metadata
Title
Research highlights from the literature
Author
Prof. Vaughan G. Macefield, Ph.D.
Publication date
01-08-2008
Publisher
D. Steinkopff-Verlag
Published in
Clinical Autonomic Research / Issue 4/2008
Print ISSN: 0959-9851
Electronic ISSN: 1619-1560
DOI
https://doi.org/10.1007/s10286-008-0485-9

Other articles of this Issue 4/2008

Clinical Autonomic Research 4/2008 Go to the issue

RESEARCH ARTICLE

The effect of depression on heart rate variability during pregnancy

RESEARCH ARTICLE

Pilot study of pyridostigmine in constipated patients with autonomic neuropathy

REVIEW ARTICLE

The origin of vasovagal syncope: to protect the heart or to escape predation?

CASE REPORT

Reversible postural tachycardia syndrome due to inadvertent overuse of Red Bull®

RESEARCH ARTICLE

Evaluation of autonomic malfunction in idiopathic normal pressure hydrocephalus

RESEARCH ARTICLE

Optimizing squatting as a physical maneuver to prevent vasovagal syncope