Skip to main content
Top
Published in: Journal of Digital Imaging 5/2018

01-10-2018

An Efficient Implementation of Deep Convolutional Neural Networks for MRI Segmentation

Authors: Farnaz Hoseini, Asadollah Shahbahrami, Peyman Bayat

Published in: Journal of Imaging Informatics in Medicine | Issue 5/2018

Login to get access

Abstract

Image segmentation is one of the most common steps in digital image processing, classifying a digital image into different segments. The main goal of this paper is to segment brain tumors in magnetic resonance images (MRI) using deep learning. Tumors having different shapes, sizes, brightness and textures can appear anywhere in the brain. These complexities are the reasons to choose a high-capacity Deep Convolutional Neural Network (DCNN) containing more than one layer. The proposed DCNN contains two parts: architecture and learning algorithms. The architecture and the learning algorithms are used to design a network model and to optimize parameters for the network training phase, respectively. The architecture contains five convolutional layers, all using 3 × 3 kernels, and one fully connected layer. Due to the advantage of using small kernels with fold, it allows making the effect of larger kernels with smaller number of parameters and fewer computations. Using the Dice Similarity Coefficient metric, we report accuracy results on the BRATS 2016, brain tumor segmentation challenge dataset, for the complete, core, and enhancing regions as 0.90, 0.85, and 0.84 respectively. The learning algorithm includes the task-level parallelism. All the pixels of an MR image are classified using a patch-based approach for segmentation. We attain a good performance and the experimental results show that the proposed DCNN increases the segmentation accuracy compared to previous techniques.
Literature
1.
go back to reference Russ JC, Matey JR, Mallinckrodt AJ, McKay S: The image processing handbook. Computers in Physics 8(2):177–178, 1994CrossRef Russ JC, Matey JR, Mallinckrodt AJ, McKay S: The image processing handbook. Computers in Physics 8(2):177–178, 1994CrossRef
2.
go back to reference Prakash RM, Kumari RSS: Spatial fuzzy C means and expectation maximization algorithms with bias correction for segmentation of MR brain images. Journal of medical systems 41(1):15, 2017CrossRef Prakash RM, Kumari RSS: Spatial fuzzy C means and expectation maximization algorithms with bias correction for segmentation of MR brain images. Journal of medical systems 41(1):15, 2017CrossRef
4.
go back to reference Steele JR, Jones AK, Clarke RK, Giordano SH, Shoemaker S: Oncology patient perceptions of the use of ionizing radiation in diagnostic imaging. Journal of the American College of Radiology 13(7):768–774, 2016CrossRefPubMed Steele JR, Jones AK, Clarke RK, Giordano SH, Shoemaker S: Oncology patient perceptions of the use of ionizing radiation in diagnostic imaging. Journal of the American College of Radiology 13(7):768–774, 2016CrossRefPubMed
5.
go back to reference Greenspan H, van Ginneken B, Summers RM: Guest editorial deep learning in medical imaging: overview and future promise of an exciting new technique. IEEE Transactions on Medical Imaging 35(5):1153–1159, 2016CrossRef Greenspan H, van Ginneken B, Summers RM: Guest editorial deep learning in medical imaging: overview and future promise of an exciting new technique. IEEE Transactions on Medical Imaging 35(5):1153–1159, 2016CrossRef
6.
go back to reference Camaiti M, Bortolotti V, Fantazzini P: Stone porosity, wettability changes and other features detected by MRI and NMR relaxometry: a more than 15year study. Magnetic Resonance in Chemistry 53(1):34–47, 2015CrossRefPubMed Camaiti M, Bortolotti V, Fantazzini P: Stone porosity, wettability changes and other features detected by MRI and NMR relaxometry: a more than 15year study. Magnetic Resonance in Chemistry 53(1):34–47, 2015CrossRefPubMed
7.
go back to reference Deliolanis NC, Ale A, Morscher S, Burton NC, Schaefer K, Radrich K, … Ntziachristos V: Deep-tissue reporter-gene imaging with fluorescence and optoacoustic tomography: a performance overview. Mol Imaging Biol 16(5): 652–660, 2014CrossRefPubMed Deliolanis NC, Ale A, Morscher S, Burton NC, Schaefer K, Radrich K, … Ntziachristos V: Deep-tissue reporter-gene imaging with fluorescence and optoacoustic tomography: a performance overview. Mol Imaging Biol 16(5): 652–660, 2014CrossRefPubMed
8.
go back to reference Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, Gul N, … Nikkhah G: NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells 28(1): 5–16, 2010 Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, Gul N, … Nikkhah G: NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells 28(1): 5–16, 2010
9.
10.
go back to reference Prajapati SJ, Jadhav KR: Brain tumor detection by various image segmentation techniques with introduction to non negative matrix factorization. Brain 4(3):600–603, 2015 Prajapati SJ, Jadhav KR: Brain tumor detection by various image segmentation techniques with introduction to non negative matrix factorization. Brain 4(3):600–603, 2015
11.
go back to reference Zhang J, Jiang W, Wang R, Wang L: Brain MR image segmentation with spatial constrained k-mean algorithm and dual-tree complex wavelet transform. Journal of medical systems 39(9):93, 2014CrossRef Zhang J, Jiang W, Wang R, Wang L: Brain MR image segmentation with spatial constrained k-mean algorithm and dual-tree complex wavelet transform. Journal of medical systems 39(9):93, 2014CrossRef
12.
go back to reference Kalchbrenner N, Grefenstette E, Blunsom P: A convolutional neural network for modelling sentences. 52nd Annual Meeting of the Association for Computational Linguistics, 2014, pp 655–665. Kalchbrenner N, Grefenstette E, Blunsom P: A convolutional neural network for modelling sentences. 52nd Annual Meeting of the Association for Computational Linguistics, 2014, pp 655–665.
13.
go back to reference Jin J, Gokhale V, Dundar A, Krishnamurthy B, Martini B, Culurciello E: An efficient implementation of deep convolutional neural networks on a mobile coprocessor. IEEE 57th International Symposium on Circuits and Systems, 2014, pp 133–136 Jin J, Gokhale V, Dundar A, Krishnamurthy B, Martini B, Culurciello E: An efficient implementation of deep convolutional neural networks on a mobile coprocessor. IEEE 57th International Symposium on Circuits and Systems, 2014, pp 133–136
14.
go back to reference Jin J, Dundar A, Bates J, Farabet C, Culurciello E: Tracking with deep neural networks. IEEE 47th Annual Conference on Information Sciences and Systems, 2013, pp 1–5 Jin J, Dundar A, Bates J, Farabet C, Culurciello E: Tracking with deep neural networks. IEEE 47th Annual Conference on Information Sciences and Systems, 2013, pp 1–5
15.
go back to reference Wells WM, Grimson WEL, Kikinis R, Jolesz FA: Adaptive segmentation of MRI data. IEEE transactions on medical imaging 15(4):429–442, 1996CrossRefPubMed Wells WM, Grimson WEL, Kikinis R, Jolesz FA: Adaptive segmentation of MRI data. IEEE transactions on medical imaging 15(4):429–442, 1996CrossRefPubMed
16.
go back to reference Gondara L: Medical image denoising using convolutional denoising autoencoders. 16th International Conference on Data Mining Workshops (ICDMW), 2016, pp. 241–246. Gondara L: Medical image denoising using convolutional denoising autoencoders. 16th International Conference on Data Mining Workshops (ICDMW), 2016, pp. 241–246.
17.
go back to reference Rekeczky C, Tahy Á, Végh Z, Roska T: CNNbased spatiotemporal nonlinear filtering and endocardial boundary detection in echocardiography. International Journal of Circuit Theory and Applications 27(1):171–207, 1999CrossRef Rekeczky C, Tahy Á, Végh Z, Roska T: CNNbased spatiotemporal nonlinear filtering and endocardial boundary detection in echocardiography. International Journal of Circuit Theory and Applications 27(1):171–207, 1999CrossRef
18.
go back to reference Zikic D, Ioannou Y, Brown M, Criminisi A: Segmentation of brain tumor tissues with convolutional neural networks. MICCAI workshop on Multimodal Brain Tumor Segmentation Challenge (BRATS) , 2014, pp 36–39 Zikic D, Ioannou Y, Brown M, Criminisi A: Segmentation of brain tumor tissues with convolutional neural networks. MICCAI workshop on Multimodal Brain Tumor Segmentation Challenge (BRATS) , 2014, pp 36–39
19.
go back to reference Wachinger C, Reuter M, Klein T: DeepNAT: deep convolutional neural network for segmenting neuroanatomy. NeuroImage, preprint arXiv:1702–08192, 2017 Wachinger C, Reuter M, Klein T: DeepNAT: deep convolutional neural network for segmenting neuroanatomy. NeuroImage, preprint arXiv:1702–08192, 2017
20.
go back to reference Pinheiro P, Collobert R: Recurrent convolutional neural networks for scene labeling. In: International Conference on Machine Learning, 2014, pp 82–90. Pinheiro P, Collobert R: Recurrent convolutional neural networks for scene labeling. In: International Conference on Machine Learning, 2014, pp 82–90.
21.
go back to reference Shelhamer E, Long J, Darrell T: Fully convolutional networks for semantic segmentation. IEEE transactions on pattern analysis and machine intelligence 39(4):640–651, 2017CrossRefPubMed Shelhamer E, Long J, Darrell T: Fully convolutional networks for semantic segmentation. IEEE transactions on pattern analysis and machine intelligence 39(4):640–651, 2017CrossRefPubMed
22.
go back to reference Zhao X, Wu Y, Song G, Li Z, Zhang Y, Fan Y: A deep learning model integrating FCNNs and CRFs for brain tumor segmentation. Medical image analysis 43:98–111, 2018CrossRefPubMed Zhao X, Wu Y, Song G, Li Z, Zhang Y, Fan Y: A deep learning model integrating FCNNs and CRFs for brain tumor segmentation. Medical image analysis 43:98–111, 2018CrossRefPubMed
23.
go back to reference Milletari F, Ahmadi SA, Kroll C, Plate A, Rozanski V, Maiostre J, … Navab N: Hough-CNN: deep learning for segmentation of deep brain regions in MRI and ultrasound. Comput Vis Image Underst, 2017 Milletari F, Ahmadi SA, Kroll C, Plate A, Rozanski V, Maiostre J, … Navab N: Hough-CNN: deep learning for segmentation of deep brain regions in MRI and ultrasound. Comput Vis Image Underst, 2017
24.
go back to reference Havaei M, Davy A, Warde-Farley D, Biard A, Courville A, Bengio Y, … Larochelle H:Brain tumor segmentation with deep neural networks. Med Image Anal 35:18–31, 2017CrossRefPubMed Havaei M, Davy A, Warde-Farley D, Biard A, Courville A, Bengio Y, … Larochelle H:Brain tumor segmentation with deep neural networks. Med Image Anal 35:18–31, 2017CrossRefPubMed
25.
go back to reference Havaei M, Guizard N, Larochelle H, Jodoin PM: Deep learning trends for focal brain pathology segmentation in MRI. Machine Learning for Health Informatics Springer International Publishing, 2016, pp 125–148 Havaei M, Guizard N, Larochelle H, Jodoin PM: Deep learning trends for focal brain pathology segmentation in MRI. Machine Learning for Health Informatics Springer International Publishing, 2016, pp 125–148
26.
go back to reference Pereira S, Pinto A, Alves V, Silva CA: Brain tumor segmentation using convolutional neural networks in MRI images. IEEE transactions on medical imaging 35(5):1240–1251, 2016CrossRefPubMed Pereira S, Pinto A, Alves V, Silva CA: Brain tumor segmentation using convolutional neural networks in MRI images. IEEE transactions on medical imaging 35(5):1240–1251, 2016CrossRefPubMed
27.
go back to reference Dvorák P, Menze BH: Local Structure Prediction with Convolutional Neural Networks for Multimodal Brain Tumor Segmentation International MICCAI Workshop on Medical Computer Vision, 2015, pp 59–71 Dvorák P, Menze BH: Local Structure Prediction with Convolutional Neural Networks for Multimodal Brain Tumor Segmentation International MICCAI Workshop on Medical Computer Vision, 2015, pp 59–71
28.
go back to reference Hoseini F, Shahbahrami A: An efficient implementation of fuzzy edge detection using GPU in MATLAB. In: High Performance Computing & Simulation (HPCS), 2015 International Conference on, 2015, pp 605–610). IEEE Hoseini F, Shahbahrami A: An efficient implementation of fuzzy edge detection using GPU in MATLAB. In: High Performance Computing & Simulation (HPCS), 2015 International Conference on, 2015, pp 605–610). IEEE
29.
go back to reference Hoseini F, Shahbahrami A: An efficient implementation of fuzzy c-means and watershed algorithms for MRI segmentation. In: Telecommunications (IST), 2016 8th International Symposium on, 2016, pp 178–184. IEEE Hoseini F, Shahbahrami A: An efficient implementation of fuzzy c-means and watershed algorithms for MRI segmentation. In: Telecommunications (IST), 2016 8th International Symposium on, 2016, pp 178–184. IEEE
30.
go back to reference Hoseini F, Shahbahrami A, Yaghoobi Notash A, Bayat P: A parallel implementation of modified fuzzy logic for breast cancer detection. Journal of Advances in Computer Research 7(2):139–148, 2016 Hoseini F, Shahbahrami A, Yaghoobi Notash A, Bayat P: A parallel implementation of modified fuzzy logic for breast cancer detection. Journal of Advances in Computer Research 7(2):139–148, 2016
31.
go back to reference Sutskever I, Martens J, Dahl G, Hinton G: On the importance of initialization and momentum in deep learning. In International conference on machine learning, 2013, pp 1139–1147 Sutskever I, Martens J, Dahl G, Hinton G: On the importance of initialization and momentum in deep learning. In International conference on machine learning, 2013, pp 1139–1147
32.
go back to reference Nesterov Y: Introductory lectures on convex optimization: a basic course. Springer Science & Business Media (Book), Vol. 87, 2013 Nesterov Y: Introductory lectures on convex optimization: a basic course. Springer Science & Business Media (Book), Vol. 87, 2013
33.
go back to reference Kingma D, Ba J: Adam: a method for stochastic optimization. 3rd International Conference for Learning Representations, preprint arXiv:1412–6980, 2015 Kingma D, Ba J: Adam: a method for stochastic optimization. 3rd International Conference for Learning Representations, preprint arXiv:1412–6980, 2015
Metadata
Title
An Efficient Implementation of Deep Convolutional Neural Networks for MRI Segmentation
Authors
Farnaz Hoseini
Asadollah Shahbahrami
Peyman Bayat
Publication date
01-10-2018
Publisher
Springer International Publishing
Published in
Journal of Imaging Informatics in Medicine / Issue 5/2018
Print ISSN: 2948-2925
Electronic ISSN: 2948-2933
DOI
https://doi.org/10.1007/s10278-018-0062-2

Other articles of this Issue 5/2018

Journal of Digital Imaging 5/2018 Go to the issue