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Journal of Imaging Informatics in Medicine

Published in:

01-10-2008

An Artificial Immune-Activated Neural Network Applied to Brain 3D MRI Segmentation

Authors: Akmal Younis, Mohamed Ibrahim, Mansur Kabuka, Nigel John

Published in: Journal of Imaging Informatics in Medicine | Special Issue 1/2008

Abstract

In this paper, a new neural network model inspired by the biological immune system functions is presented. The model, termed Artificial Immune-Activated Neural Network (AIANN), extracts classification knowledge from a training data set, which is then used to classify input patterns or vectors. The AIANN is based on a neuron activation function whose behavior is conceptually modeled after the chemical bonds between the receptors and epitopes in the biological immune system. The bonding is controlled through an energy measure to ensure accurate recognition. The AIANN model was applied to the segmentation of 3-dimensional magnetic resonance imaging (MRI) data of the brain and a contextual basis was developed for the segmentation problem. Evaluation of the segmentation results was performed using both real MRI data obtained from the Center for Morphometric Analysis at Massachusetts General Hospital and simulated MRI data generated using the McGill University BrainWeb MRI simulator. Experimental results demonstrated that the AIANN model attained higher average results than those obtained using published methods for real MRI data and simulated MRI data, especially at low levels of noise.

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Title: An Artificial Immune-Activated Neural Network Applied to Brain 3D MRI Segmentation
Authors: Akmal Younis
Mohamed Ibrahim
Mansur Kabuka
Nigel John
Publication date: 01-10-2008
Publisher: Springer-Verlag
Published in: Journal of Imaging Informatics in Medicine / Issue Special Issue 1/2008
Print ISSN: 2948-2925
Electronic ISSN: 2948-2933
DOI: https://doi.org/10.1007/s10278-007-9081-0

At a glance: The STEP trials

Springer Medicine

An Artificial Immune-Activated Neural Network Applied to Brain 3D MRI Segmentation

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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