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The European Journal of Health Economics

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Open Access 01-06-2019 | Common Pemphigus | Original Paper

Subjective well-being in patients with pemphigus: a path analysis

Authors: Ariel Mitev, Fanni Rencz, Béla Tamási, Krisztina Hajdu, Márta Péntek, László Gulácsi, Andrea Szegedi, Zsuzsanna Bata-Csörgő, Ágnes Kinyó, Miklós Sárdy, Valentin Brodszky

Published in: The European Journal of Health Economics | Special Issue 1/2019

Abstract

Background

Pemphigus is a chronic autoimmune blistering disease of the skin and mucosa severely impairing patients’ health-related quality of life (HRQoL). To date, no studies have measured subjective well-being in terms of life satisfaction in pemphigus. Our main objective was to evaluate satisfaction with life in patients with pemphigus, and to analyse its relationship with clinical severity and HRQoL.

Methods

A cross-sectional survey was carried out enrolling 77 patients with pemphigus. Subjective well-being was measured using the Satisfaction with Life Scale (SWLS). HRQoL was assessed by the Dermatology Life Quality Index (DLQI) and EQ-5D-5L. Disease severity was measured by Autoimmune Bullous Skin Disorder Intensity Score (ABSIS).

Results

Mean ABSIS, DLQI, EQ-5D-5L and SWLS scores of patients were 11.7 (SD 17.3), 5.4 (6.8), 0.84 (0.22) and 4.76 (SD 1.52), respectively. The proportion of patients indicating extreme dissatisfaction, dissatisfaction, slightly below average in life satisfaction, average satisfaction, high satisfaction and very high satisfaction with life was 6 (7.8%), 5 (6.5%), 14 (18.2%), 16 (20.8%), 21 (27.3%) and 15 (19.5%), respectively. Life satisfaction was independent from age, gender, level of education and type of disease. A path analysis revealed that there was no direct relationship between ABSIS and SWLS (beta = − 0.09; p = 0.428); however, the following indirect path was confirmed: ABSIS → DLQI → EQ-5D-5L → SWLS.

Conclusions

Disease severity and HRQoL measures regularly used to assess patients’ health status may be complemented with a measure of subjective well-being, such as SWLS, to achieve a more holistic assessment of patients’ lives and optimise pemphigus care.

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Title: Subjective well-being in patients with pemphigus: a path analysis
Authors: Ariel Mitev
Fanni Rencz
Béla Tamási
Krisztina Hajdu
Márta Péntek
László Gulácsi
Andrea Szegedi
Zsuzsanna Bata-Csörgő
Ágnes Kinyó
Miklós Sárdy
Valentin Brodszky
Publication date: 01-06-2019
Publisher: Springer Berlin Heidelberg
Keywords: Common Pemphigus
Pemphigus Foliaceus
Pemphigus
Published in: The European Journal of Health Economics / Issue Special Issue 1/2019
Print ISSN: 1618-7598
Electronic ISSN: 1618-7601
DOI: https://doi.org/10.1007/s10198-019-01067-w

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Subjective well-being in patients with pemphigus: a path analysis

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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