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The Journal of Headache and Pain

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Open Access 01-10-2012 | Brief Report

Psychotic aura symptoms in familial hemiplegic migraine type 2 (ATP1A2)

Authors: José Barros, Alexandre Mendes, Ilda Matos, José Pereira-Monteiro

Published in: The Journal of Headache and Pain | Issue 7/2012

Abstract

Introduction

Neuropsychological symptoms are rare in familial hemiplegic migraine (FHM). There are no reports of psychotic symptoms in FHM type 2 (ATP1A2). We examined a family with a FHM phenotype due to a M731T mutation in ATP1A2. A 10-year follow-up allowed us to observe complex auras, including psychotic symptoms in two siblings.

Case report

Male, 48 years old, with an aura that included complex illusions with a feeling of time travelling, coincident with other aura features. The aura was regarded as mystical by the patient. Female, 38 years old, with a complex migraine aura, during which she believed she had the ability to time travel and was being followed by lobbyists who wanted to steal this ability from her.

Discussion

FHM type 2 must be included in the list of differential diagnoses of acute psychosis in patients with a previous history of migraine aura.

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Title: Psychotic aura symptoms in familial hemiplegic migraine type 2 (ATP1A2)
Authors: José Barros
Alexandre Mendes
Ilda Matos
José Pereira-Monteiro
Publication date: 01-10-2012
Publisher: Springer Milan
Published in: The Journal of Headache and Pain / Issue 7/2012
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI: https://doi.org/10.1007/s10194-012-0462-5

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Psychotic aura symptoms in familial hemiplegic migraine type 2 (ATP1A2)

Abstract

Introduction

Case report

Discussion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Introduction

Case report

Discussion

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