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Open Access 01-12-2011 | Original

Clinical features of headache patients with fibromyalgia comorbidity

Authors: Marina de Tommaso, Antonio Federici, Claudia Serpino, Eleonora Vecchio, Giovanni Franco, Michele Sardaro, Marianna Delussi, Paolo Livrea

Published in: The Journal of Headache and Pain | Issue 6/2011

Abstract

Our previous study assessed the prevalence of fibromyalgia (FM) syndrome in migraine and tension-type headache. We aimed to update our previous results, considering a larger cohort of primary headache patients who came for the first time at our tertiary headache ambulatory. A consecutive sample of 1,123 patients was screened. Frequency of FM in the main groups and types of primary headaches; discriminating factor for FM comorbidity derived from headache frequency and duration, age, anxiety, depression, headache disability, allodynia, pericranial tenderness, fatigue, quality of life and sleep, and probability of FM membership in groups; and types of primary headaches were assessed. FM was present in 174 among a total of 889 included patients. It prevailed in the tension-type headache main group (35%, p < 0.0001) and chronic tension-type headache subtype (44.3%, p < 0.0001). Headache frequency, anxiety, pericranial tenderness, poor sleep quality, and physical disability were the best discriminating variables for FM comorbidity, with 81.2% sensitivity. Patients presenting with chronic migraine and chronic tension-type headache had a higher probability of sharing the FM profile (Bonferroni test, p < 0.01). A phenotypic profile where headache frequency concurs with anxiety, sleep disturbance, and pericranial tenderness should be individuated to detect the development of diffuse pain in headache patients.

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Title: Clinical features of headache patients with fibromyalgia comorbidity
Authors: Marina de Tommaso
Antonio Federici
Claudia Serpino
Eleonora Vecchio
Giovanni Franco
Michele Sardaro
Marianna Delussi
Paolo Livrea
Publication date: 01-12-2011
Publisher: Springer Milan
Published in: The Journal of Headache and Pain / Issue 6/2011
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI: https://doi.org/10.1007/s10194-011-0377-6

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Clinical features of headache patients with fibromyalgia comorbidity

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