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The Journal of Headache and Pain
Published in: The Journal of Headache and Pain 5/2010

Open Access 01-10-2010 | Review Article

Verisimilitude (or “truthlikeness”) as an alternative to pro and cons: migraine and cluster headache mechanisms

Author: Peer Carsten Tfelt-Hansen

Published in: The Journal of Headache and Pain | Issue 5/2010

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Abstract

Calculating verisimilitude (or “truthlikeness”) ad modum Popper is a quantitative alternative to the usual pros and cons in migraine and cluster headache mechanisms. The following items were evaluated: dilation of large cranial arteries during migraine; CGRP increase during migraine; migraine as a brain disorder; aura and migraine headache; brain stem activation during migraine; rCBF in migraine without aura; NO and pathophysiology of migraine; neurogenic inflammation and migraine; aura in cluster headache; and hypothalamic activation in cluster headache. It is concluded that verisimilitude calculations can be helpful when judging pathophysiological problems in migraine and cluster headache.
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Metadata
Title
Verisimilitude (or “truthlikeness”) as an alternative to pro and cons: migraine and cluster headache mechanisms
Author
Peer Carsten Tfelt-Hansen
Publication date
01-10-2010
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue 5/2010
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1007/s10194-010-0232-1

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