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Published in: The Journal of Headache and Pain 2/2008

Open Access 01-04-2008 | Brief Report

Influence of physiologic hormonal modification and of hormonal treatment in a patient with a history of migraine with aura

Authors: Ferdinando Maggioni, Antonio Palmieri, Michele Tropea, Giorgio Zanchin

Published in: The Journal of Headache and Pain | Issue 2/2008

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Abstract

We present the case of 48-year-old woman suffering from migraine with aura (MA) since menarche. During her life the patient frequently presented catamenial MA attacks with an increasing frequency during pregnancy in particular in the second and third trimesters, and then during breast-feeding. Treatment with oral contraceptive (OC) for endometriosis and later with cyclophosphamide, methotrexate, fluorouracil (CMF) for breast cancer produced a higher number of attacks. Instead, she referred an improvement with gonadotropin releasing hormone agonist (GnRH-a) for the treatment of endometriosis and then with tamoxifen as hormonal therapy after mastectomy and chemotherapy for breast cancer. We highlight the importance of physiological hormonal modification and hormonal therapies on the course of MA.
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Metadata
Title
Influence of physiologic hormonal modification and of hormonal treatment in a patient with a history of migraine with aura
Authors
Ferdinando Maggioni
Antonio Palmieri
Michele Tropea
Giorgio Zanchin
Publication date
01-04-2008
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue 2/2008
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1007/s10194-008-0018-x

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