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International Journal of Clinical Oncology
Published in: International Journal of Clinical Oncology 6/2010

01-12-2010 | Case Report

A case of metastatic testicular cancer complicated by pulmonary hemorrhage due to choriocarcinoma syndrome

Authors: Shuya Kandori, Koji Kawai, Yoshiharu Fukuhara, Akira Joraku, Naoto Miyanaga, Toru Shimazui, Hideyuki Akaza

Published in: International Journal of Clinical Oncology | Issue 6/2010

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Abstract

A 40-year-old man was referred to our hospital for treatment of metastatic testicular cancer. Computerized tomography revealed multiple lung, liver, and retroperitoneal lymph node metastases. In addition, magnetic resonance imaging revealed multiple brain metastases. Induction chemotherapy with bleomycin, etoposide, and cisplatin was started the day after a high orchiectomy. The pathological diagnosis of the surgical specimen was yolk sac carcinoma. The serum human chorionic gonadotropin (hCG) was markedly increased to 630,000 mIU/ml, which suggested the presence of a choriocarcinoma element at metastatic sites. The patient subsequently suffered respiratory failure due to pulmonary hemorrhage. Intensive supportive care prevented a fatal outcome. Physicians who treat advanced testicular tumors should be aware of the potential complication of acute pulmonary hemorrhage, called choriocarcinoma syndrome, in cases with a high hCG level, which indicates a rapidly progressive and high-volume choriocarcinoma.
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Metadata
Title
A case of metastatic testicular cancer complicated by pulmonary hemorrhage due to choriocarcinoma syndrome
Authors
Shuya Kandori
Koji Kawai
Yoshiharu Fukuhara
Akira Joraku
Naoto Miyanaga
Toru Shimazui
Hideyuki Akaza
Publication date
01-12-2010
Publisher
Springer Japan
Published in
International Journal of Clinical Oncology / Issue 6/2010
Print ISSN: 1341-9625
Electronic ISSN: 1437-7772
DOI
https://doi.org/10.1007/s10147-010-0092-3

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