Skip to main content
Top
Published in: Neurosurgical Review 1/2010

01-01-2010 | Review

Endovascular management of spinal vascular malformations

Authors: Timo Krings, Armin K. Thron, Sasikhan Geibprasert, Ronit Agid, Franz J. Hans, Pierre L. Lasjaunias, Marcus H. T. Reinges

Published in: Neurosurgical Review | Issue 1/2010

Login to get access

Abstract

Spinal vascular malformations are rare diseases with a wide variety of neurological presentations. In this article, arteriovenous malformations (both from the fistulous and glomerular type) and spinal dural arteriovenous fistulae are described and an overview about their imaging features on magnetic resonance imaging (MRI) and digital subtraction angiography is given. Clinical differential diagnoses, the neurological symptomatology and the potential therapeutic approaches of these diseases which vary depending on the underlying pathology are given. Although MRI constitutes the diagnostic modality of first choice in suspected spinal vascular malformation, a definite diagnosis of the disease and therefore the choice of suited therapeutic approach rests on selective spinal angiography. Treatment in symptomatic patients offers an improvement in the prognosis. In most spinal vascular malformations, the endovascular approach is the method of first choice; in selected cases, a combined or surgical therapy may be considered.
Literature
1.
2.
go back to reference Aminoff MJ, Logue V (1974) The prognosis of patients with spinal vascular malformations. Brain 97:211–218CrossRefPubMed Aminoff MJ, Logue V (1974) The prognosis of patients with spinal vascular malformations. Brain 97:211–218CrossRefPubMed
3.
go back to reference Andres RH, Barth A, Guzman R et al (2008) Endovascular and surgical treatment of spinal dural arteriovenous fistulas. Neuroradiology 50:869–876CrossRefPubMed Andres RH, Barth A, Guzman R et al (2008) Endovascular and surgical treatment of spinal dural arteriovenous fistulas. Neuroradiology 50:869–876CrossRefPubMed
4.
go back to reference Behrens S, Thron A (1999) Long-term follow-up and outcome in patients treated for spinal dural arteriovenous fistula. J Neurol 246:181–185CrossRefPubMed Behrens S, Thron A (1999) Long-term follow-up and outcome in patients treated for spinal dural arteriovenous fistula. J Neurol 246:181–185CrossRefPubMed
5.
go back to reference Biondi A, Merland JJ, Reizine D et al (1990) Embolization with particles in thoracic intramedullary arteriovenous malformations: long-term angiographic and clinical results. Radiology 177:651–658PubMed Biondi A, Merland JJ, Reizine D et al (1990) Embolization with particles in thoracic intramedullary arteriovenous malformations: long-term angiographic and clinical results. Radiology 177:651–658PubMed
6.
go back to reference Bradac GB, Daniele D, Riva A et al (1994) Spinal dural arteriovenous fistulas: an underestimated cause of myelopathy. Eur Neurol 34:87–94CrossRefPubMed Bradac GB, Daniele D, Riva A et al (1994) Spinal dural arteriovenous fistulas: an underestimated cause of myelopathy. Eur Neurol 34:87–94CrossRefPubMed
7.
go back to reference Criscuolo GR, Oldfield EH, Doppman JL (1989) Reversible acute and subacute myelopathy in patients with dural arteriovenous fistulas. Foix-Alajouanine syndrome reconsidered. J Neurosurg 70:354–359CrossRefPubMed Criscuolo GR, Oldfield EH, Doppman JL (1989) Reversible acute and subacute myelopathy in patients with dural arteriovenous fistulas. Foix-Alajouanine syndrome reconsidered. J Neurosurg 70:354–359CrossRefPubMed
8.
go back to reference De Marco JK, Dillon WP, Halback VV et al (1990) Dural arteriovenous fistulas: evaluation with MR imaging. Radiology 175:193–199PubMed De Marco JK, Dillon WP, Halback VV et al (1990) Dural arteriovenous fistulas: evaluation with MR imaging. Radiology 175:193–199PubMed
9.
go back to reference Djindjian R, Cophignon J, Rey A et al (1973) Superselective arteriographic embolization by the femoral route in neuroradiology. Study of 50 cases. II. Embolization in vertebromedullary pathology. Neuroradiology 6:132–142CrossRefPubMed Djindjian R, Cophignon J, Rey A et al (1973) Superselective arteriographic embolization by the femoral route in neuroradiology. Study of 50 cases. II. Embolization in vertebromedullary pathology. Neuroradiology 6:132–142CrossRefPubMed
10.
go back to reference Doppman JL, Di Chiro G, Ommaya A (1968) Obliteration of spinal-cord arteriovenous malformation by percutaneous embolisation. Lancet 1:477CrossRefPubMed Doppman JL, Di Chiro G, Ommaya A (1968) Obliteration of spinal-cord arteriovenous malformation by percutaneous embolisation. Lancet 1:477CrossRefPubMed
11.
go back to reference Doppman JL, Di Chiro G, Dwyer AJ et al (1987) Magnetic resonance imaging of spinal arteriovenous malformations. J Neurosurg 66:830–834CrossRefPubMed Doppman JL, Di Chiro G, Dwyer AJ et al (1987) Magnetic resonance imaging of spinal arteriovenous malformations. J Neurosurg 66:830–834CrossRefPubMed
12.
go back to reference Gomori JM, Grossman RI, Yu-Ip C et al (1987) NMR relaxation times of blood: dependence on field strength, oxidation state, and cell integrity. J Comput Assist Tomogr 11:684–690CrossRefPubMed Gomori JM, Grossman RI, Yu-Ip C et al (1987) NMR relaxation times of blood: dependence on field strength, oxidation state, and cell integrity. J Comput Assist Tomogr 11:684–690CrossRefPubMed
13.
go back to reference Grunwald I, Thron A, Reith W (2001) Spinal angiography: vascular anatomy, technique and indications. Radiologe 41:961–967CrossRefPubMed Grunwald I, Thron A, Reith W (2001) Spinal angiography: vascular anatomy, technique and indications. Radiologe 41:961–967CrossRefPubMed
14.
go back to reference Heros RC, Debrun GM, Ojemann RG et al (1986) Direct spinal arteriovenous fistula: a new type of spinal AVM. Case report. J Neurosurg 64:134–139CrossRefPubMed Heros RC, Debrun GM, Ojemann RG et al (1986) Direct spinal arteriovenous fistula: a new type of spinal AVM. Case report. J Neurosurg 64:134–139CrossRefPubMed
15.
go back to reference Huffmann BC, Gilsbach JM, Thron A (1995) Spinal dural arteriovenous fistulas: a plea for neurosurgical treatment. Acta Neurochir (Wien) 135:44–51CrossRef Huffmann BC, Gilsbach JM, Thron A (1995) Spinal dural arteriovenous fistulas: a plea for neurosurgical treatment. Acta Neurochir (Wien) 135:44–51CrossRef
16.
go back to reference Hurst RW, Grossman RI (2000) Peripheral spinal cord hypointensity on T2-weighted MR images: a reliable imaging sign of venous hypertensive myelopathy. AJNR Am J Neuroradiol 21:781–786PubMed Hurst RW, Grossman RI (2000) Peripheral spinal cord hypointensity on T2-weighted MR images: a reliable imaging sign of venous hypertensive myelopathy. AJNR Am J Neuroradiol 21:781–786PubMed
17.
go back to reference Hurst RW, Kenyon LC, Lavi E et al (1995) Spinal dural arteriovenous fistula: the pathology of venous hypertensive myelopathy. Neurology 45:1309–1313PubMed Hurst RW, Kenyon LC, Lavi E et al (1995) Spinal dural arteriovenous fistula: the pathology of venous hypertensive myelopathy. Neurology 45:1309–1313PubMed
18.
go back to reference Kataoka H, Miyamoto S, Nagata I et al (2001) Venous congestion is a major cause of neurological deterioration in spinal arteriovenous malformations. Neurosurgery 48:1224–1229 discussion 1229–1230CrossRefPubMed Kataoka H, Miyamoto S, Nagata I et al (2001) Venous congestion is a major cause of neurological deterioration in spinal arteriovenous malformations. Neurosurgery 48:1224–1229 discussion 1229–1230CrossRefPubMed
19.
go back to reference Koenig E, Thron A, Schrader V et al (1989) Spinal arteriovenous malformations and fistulae: clinical, neuroradiological and neurophysiological findings. J Neurol 236:260–266CrossRefPubMed Koenig E, Thron A, Schrader V et al (1989) Spinal arteriovenous malformations and fistulae: clinical, neuroradiological and neurophysiological findings. J Neurol 236:260–266CrossRefPubMed
20.
go back to reference Krings T, Geibprasert S (2009) Spinal dural arteriovenous fistulas. AJNR Am J Neuroradiol 39:639–648CrossRef Krings T, Geibprasert S (2009) Spinal dural arteriovenous fistulas. AJNR Am J Neuroradiol 39:639–648CrossRef
21.
go back to reference Krings T, Chng SM, Ozanne A et al (2005) Hereditary hemorrhagic telangiectasia in children: endovascular treatment of neurovascular malformations: results in 31 patients. Neuroradiology 47:946–954CrossRefPubMed Krings T, Chng SM, Ozanne A et al (2005) Hereditary hemorrhagic telangiectasia in children: endovascular treatment of neurovascular malformations: results in 31 patients. Neuroradiology 47:946–954CrossRefPubMed
22.
23.
go back to reference Krings T, Ozanne A, Chng SM et al (2005) Neurovascular phenotypes in hereditary haemorrhagic telangiectasia patients according to age. Review of 50 consecutive patients aged 1 day-60 years. Neuroradiology 47:711–720CrossRefPubMed Krings T, Ozanne A, Chng SM et al (2005) Neurovascular phenotypes in hereditary haemorrhagic telangiectasia patients according to age. Review of 50 consecutive patients aged 1 day-60 years. Neuroradiology 47:711–720CrossRefPubMed
24.
go back to reference Lasjaunias PL, Berenstein A, ter Brugge K (2001) Surgical neuroangiography, vol. 1. Clinical vascular anatomy and variations. Springer, Berlin Lasjaunias PL, Berenstein A, ter Brugge K (2001) Surgical neuroangiography, vol. 1. Clinical vascular anatomy and variations. Springer, Berlin
25.
go back to reference Lee TT, Gromelski EB, Bowen BC et al (1998) Diagnostic and surgical management of spinal dural arteriovenous fistulas. Neurosurgery 43:242–246 discussion 246–247CrossRefPubMed Lee TT, Gromelski EB, Bowen BC et al (1998) Diagnostic and surgical management of spinal dural arteriovenous fistulas. Neurosurgery 43:242–246 discussion 246–247CrossRefPubMed
26.
go back to reference Mourier KL, Gobin YP, George B et al (1993) Intradural perimedullary arteriovenous fistulae: results of surgical and endovascular treatment in a series of 35 cases. Neurosurgery 32:885–891 discussion 891CrossRefPubMed Mourier KL, Gobin YP, George B et al (1993) Intradural perimedullary arteriovenous fistulae: results of surgical and endovascular treatment in a series of 35 cases. Neurosurgery 32:885–891 discussion 891CrossRefPubMed
27.
go back to reference Niimi Y, Berenstein A, Setton A et al (1997) Embolization of spinal dural arteriovenous fistulae: results and follow-up. Neurosurgery 40:675–682 discussion 682–673CrossRefPubMed Niimi Y, Berenstein A, Setton A et al (1997) Embolization of spinal dural arteriovenous fistulae: results and follow-up. Neurosurgery 40:675–682 discussion 682–673CrossRefPubMed
28.
go back to reference Rodesch G, Hurth M, Alvarez H et al (2002) Classification of spinal cord arteriovenous shunts: proposal for a reappraisal—the Bicetre experience with 155 consecutive patients treated between 1981 and 1999. Neurosurgery 51:374–379CrossRefPubMed Rodesch G, Hurth M, Alvarez H et al (2002) Classification of spinal cord arteriovenous shunts: proposal for a reappraisal—the Bicetre experience with 155 consecutive patients treated between 1981 and 1999. Neurosurgery 51:374–379CrossRefPubMed
29.
go back to reference Rodesch G, Hurth M, Alvarez H et al (2003) Embolization of spinal cord arteriovenous shunts: morphological and clinical follow-up and results—review of 69 consecutive cases. Neurosurgery 53:40–49CrossRefPubMed Rodesch G, Hurth M, Alvarez H et al (2003) Embolization of spinal cord arteriovenous shunts: morphological and clinical follow-up and results—review of 69 consecutive cases. Neurosurgery 53:40–49CrossRefPubMed
30.
go back to reference Rodesch G, Hurth M, Alvarez H et al (2005) Spinal cord intradural arteriovenous fistulae: anatomic, clinical, and therapeutic considerations in a series of 32 consecutive patients seen between 1981 and 2000 with emphasis on endovascular therapy. Neurosurgery 57:973–983CrossRefPubMed Rodesch G, Hurth M, Alvarez H et al (2005) Spinal cord intradural arteriovenous fistulae: anatomic, clinical, and therapeutic considerations in a series of 32 consecutive patients seen between 1981 and 2000 with emphasis on endovascular therapy. Neurosurgery 57:973–983CrossRefPubMed
31.
go back to reference Rosenblum B, Oldfield EH, Doppman JL et al (1987) Spinal arteriovenous malformations: a comparison of dural arteriovenous fistulas and intradural AVM's in 81 patients. J Neurosurg 67:795–802CrossRefPubMed Rosenblum B, Oldfield EH, Doppman JL et al (1987) Spinal arteriovenous malformations: a comparison of dural arteriovenous fistulas and intradural AVM's in 81 patients. J Neurosurg 67:795–802CrossRefPubMed
32.
go back to reference Steinmetz MP, Chow MM, Krishnaney AA et al (2004) Outcome after the treatment of spinal dural arteriovenous fistulae: a contemporary single-institution series and meta-analysis. Neurosurgery 55:77–87 discussion 87–88CrossRefPubMed Steinmetz MP, Chow MM, Krishnaney AA et al (2004) Outcome after the treatment of spinal dural arteriovenous fistulae: a contemporary single-institution series and meta-analysis. Neurosurgery 55:77–87 discussion 87–88CrossRefPubMed
33.
go back to reference Thron A (1988) Vascular anatomy of the spinal cord: neuroradiological investigations and clinical syndromes. Springer, Berlin Thron A (1988) Vascular anatomy of the spinal cord: neuroradiological investigations and clinical syndromes. Springer, Berlin
35.
go back to reference Thron A, Caplan LR (2003) Vascular malformations and interventional neuroradiology of the spinal cord. In: Brandt T, Caplan LR, Dichgans J et al (eds) Neurological disorders course and treatment. Academic, Amsterdam, pp 517–528CrossRef Thron A, Caplan LR (2003) Vascular malformations and interventional neuroradiology of the spinal cord. In: Brandt T, Caplan LR, Dichgans J et al (eds) Neurological disorders course and treatment. Academic, Amsterdam, pp 517–528CrossRef
36.
go back to reference Thron A, Otto J, Schroeder JM (1990) Functional anatomy of the dural segment of spinal cord draining veins. A histological and microangiographic study. In: du Boulay G (ed) Symposium neuroradiologicum. Springer, London, p 323 Thron A, Otto J, Schroeder JM (1990) Functional anatomy of the dural segment of spinal cord draining veins. A histological and microangiographic study. In: du Boulay G (ed) Symposium neuroradiologicum. Springer, London, p 323
37.
38.
go back to reference Van Dijk JM, TerBrugge KG, Willinsky RA et al (2002) Multidisciplinary management of spinal dural arteriovenous fistulas: clinical presentation and long-term follow-up in 49 patients. Stroke 33:1578–1583CrossRefPubMed Van Dijk JM, TerBrugge KG, Willinsky RA et al (2002) Multidisciplinary management of spinal dural arteriovenous fistulas: clinical presentation and long-term follow-up in 49 patients. Stroke 33:1578–1583CrossRefPubMed
Metadata
Title
Endovascular management of spinal vascular malformations
Authors
Timo Krings
Armin K. Thron
Sasikhan Geibprasert
Ronit Agid
Franz J. Hans
Pierre L. Lasjaunias
Marcus H. T. Reinges
Publication date
01-01-2010
Publisher
Springer-Verlag
Published in
Neurosurgical Review / Issue 1/2010
Print ISSN: 0344-5607
Electronic ISSN: 1437-2320
DOI
https://doi.org/10.1007/s10143-009-0204-6

Other articles of this Issue 1/2010

Neurosurgical Review 1/2010 Go to the issue

Acknowledgement to Referees

Referees 2009