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Lasers in Medical Science
Published in: Lasers in Medical Science 1/2022

01-02-2022 | Melasma | Original Article

Efficacy and safety of 755 nm Q-switched Alexandrite Laser for Hori’s nevus: a retrospective analysis of 482 Chinese women

Authors: Lining Huang, Yiping Zhong, Tingting Yan, Zhenfeng Liu, Bin Yang, Mao-Qiang Man

Published in: Lasers in Medical Science | Issue 1/2022

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Abstract

To evaluate the efficacy and safety of 755 nm Q-Switched alexandrite laser for Hori’s nevus in a large cohort of Chinese women. We retrospectively analyzed the efficacy and safety of 755 nm Q-Switched alexandrite laser for Hori’s nevus. Reduction in pigment was evaluated using a 4-score method. A total of 482 patients, aged 16 to 52 years, were included in this analysis. Patients were treated with 755 nm Q-Switched alexandrite laser at fluence levels of 5–8 J/cm2 for 2–4 treatment sessions. Following the treatments, 53% of patients showed over 75% reductions in pigment while 50–75% reductions in pigment were observed in 28% of patients. The rest displayed less than 50% improvements. Efficacy was positively correlated with the number of treatment sessions (p < 0.0001). Adverse reactions were temporary, mild erythema, and edema. A small portion of patients (15%) had hyperpigmentation, which disappeared within 2–6 months. 755 nm Q-Switched alexandrite laser is safe and has moderate benefits for Hori’s nevus. Because its efficacy is positively correlated with the number of treatment sessions, increase in treatment sessions possibly could achieve a better outcome.
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Metadata
Title
Efficacy and safety of 755 nm Q-switched Alexandrite Laser for Hori’s nevus: a retrospective analysis of 482 Chinese women
Authors
Lining Huang
Yiping Zhong
Tingting Yan
Zhenfeng Liu
Bin Yang
Mao-Qiang Man
Publication date
01-02-2022
Publisher
Springer London
Published in
Lasers in Medical Science / Issue 1/2022
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-021-03257-6

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