Skip to main content
Top
Published in: Lasers in Medical Science 7/2019

01-09-2019 | Skin Aging | Original Article

The skin rejuvenation associated treatment—Fraxel laser, Microbotox, and low G prime hyaluronic acid: preliminary results

Authors: Dario Bertossi, Giorgio Giampaoli, Alessandra Lucchese, Maurizio Manuelli, Massimo Albanese, Riccardo Nocini, Pier Francesco Nocini

Published in: Lasers in Medical Science | Issue 7/2019

Login to get access

Abstract

Minimally invasive facial rejuvenation procedures reached an all-time high in the 2016. This reveals a growing interest in a smoother, younger, and tighter look accessible using the esthetic medicine tools like botulinum toxin and dermal filler injections, laser, and microdermabrasion. Forty-five patients from 35 to 52 years old (medium age 43.8), 38 women and 7 men underwent 5 sessions of Fraxel laser, 1 session of very low G prime HA, and Microbotox injection treatments from January 2016 and January 2017, were included in this study. In this study, we demonstrated that the usage of three treatments together, like mBTX, Volite, and Fractional laser, have a better result despite every single technique alone. The clinical result showed 98% (44 patients, 6 males, 38 females) of the patients had a smoother skin surface, brighter, more hydrated, and elastic skin; 68% of our patients (31 patients, 5 males, 26 females) showed less skin defects and staining as well as less small wrinkles, thanks to Fraxel laser treatment; 98% (44 patients, 6 males, 38 females) showed tighter skin with less sebaceous gland secretion. The aim of this study was to demonstrate that the combination of three techniques acts better and faster than single treatment to contrast facial aging and to improve skin texture and quality.
Literature
1.
go back to reference Bertossi D, Albanese M, Turra M, Favero V, Nocini P, Lucchese A (2013) Combined rhinoplasty and genioplasty: long-term follow-up. JAMA Facial Plast Surg 15(3):192–197CrossRefPubMed Bertossi D, Albanese M, Turra M, Favero V, Nocini P, Lucchese A (2013) Combined rhinoplasty and genioplasty: long-term follow-up. JAMA Facial Plast Surg 15(3):192–197CrossRefPubMed
2.
go back to reference Lucchese A, Manuelli M, Bassani L, Albertini P, Matarese G, Perillo L et al (2015) Fiber reinforced composites orthodontic retainers. Minerva Stomatol 64(6):323–333PubMed Lucchese A, Manuelli M, Bassani L, Albertini P, Matarese G, Perillo L et al (2015) Fiber reinforced composites orthodontic retainers. Minerva Stomatol 64(6):323–333PubMed
3.
go back to reference Bertossi D, Lucchese A, Albanese M, Turra M, Faccioni F, Nocini P et al (2013) Piezosurgery versus conventional osteotomy in orthognatic surgery: a paradigm shift in treatment. J Craniofac Surg 24(5):1763–1766CrossRefPubMed Bertossi D, Lucchese A, Albanese M, Turra M, Faccioni F, Nocini P et al (2013) Piezosurgery versus conventional osteotomy in orthognatic surgery: a paradigm shift in treatment. J Craniofac Surg 24(5):1763–1766CrossRefPubMed
4.
go back to reference Ganceviciene R, Liakou AI, Theodoridis A, Makrantonaki E, Zouboulis CC (2012) Skin anti-aging strategies. Dermatoendocrinology 4(3):308–319CrossRef Ganceviciene R, Liakou AI, Theodoridis A, Makrantonaki E, Zouboulis CC (2012) Skin anti-aging strategies. Dermatoendocrinology 4(3):308–319CrossRef
5.
go back to reference Wu WT (2015) Microbotox of the lower face and neck: evolution of a personal technique and its clinical effects. Plast Reconstr Surg 136(5 Suppl):92S–100SCrossRefPubMed Wu WT (2015) Microbotox of the lower face and neck: evolution of a personal technique and its clinical effects. Plast Reconstr Surg 136(5 Suppl):92S–100SCrossRefPubMed
6.
go back to reference Walgrave S, Zelickson B, Childs J, Altshuler G, Erofeev A, Yaroslavsky I, Kist D, Counters J (2008) Pilot investigation of the correlation between histological and clinical effects of infrared fractional resurfacing lasers. Dermatol Surg 34(11):1443–1453PubMed Walgrave S, Zelickson B, Childs J, Altshuler G, Erofeev A, Yaroslavsky I, Kist D, Counters J (2008) Pilot investigation of the correlation between histological and clinical effects of infrared fractional resurfacing lasers. Dermatol Surg 34(11):1443–1453PubMed
7.
go back to reference Fabi S, Pavicic T, Braz A, Green JB, Seo K, van Loghem JA (2017) Combined aesthetic interventions for prevention of facial ageing, and restoration and beautification of face and body. Clin Cosmet Investig Dermatol 10:423–429CrossRefPubMedPubMedCentral Fabi S, Pavicic T, Braz A, Green JB, Seo K, van Loghem JA (2017) Combined aesthetic interventions for prevention of facial ageing, and restoration and beautification of face and body. Clin Cosmet Investig Dermatol 10:423–429CrossRefPubMedPubMedCentral
8.
go back to reference Bertossi D, Mortellaro C, Nocini P (2016) New clinical analysis and device for Botox injections. J Craniofac Surg 27(6):1554–1557CrossRefPubMed Bertossi D, Mortellaro C, Nocini P (2016) New clinical analysis and device for Botox injections. J Craniofac Surg 27(6):1554–1557CrossRefPubMed
9.
go back to reference Cohen SR, Goodacre A, Lim S, Johnston J, Henssler C, Jeffers B, Saad A, Leong T (2017) Clinical outcomes and complications associated with fractional lasers: a review of 730Patients. Aesthet Plast Surg 41(1):171–178CrossRef Cohen SR, Goodacre A, Lim S, Johnston J, Henssler C, Jeffers B, Saad A, Leong T (2017) Clinical outcomes and complications associated with fractional lasers: a review of 730Patients. Aesthet Plast Surg 41(1):171–178CrossRef
10.
go back to reference Pham AM, Greene RM, Woolery-Lloyd H, Kaufman J, Grunebaum LD (2011) 1550-nm nonablative laser resurfacing for facial surgical scars. Arch Facial Plast Surg 13(3):203–210CrossRefPubMed Pham AM, Greene RM, Woolery-Lloyd H, Kaufman J, Grunebaum LD (2011) 1550-nm nonablative laser resurfacing for facial surgical scars. Arch Facial Plast Surg 13(3):203–210CrossRefPubMed
11.
go back to reference Bertossi D, Tessari G, Girolomoni G, Nocini PF (2016) The facial grid analysis for filler injection: a cohort study of 300 patients. G Ital Dermatol Venereol 151(5):467–472PubMed Bertossi D, Tessari G, Girolomoni G, Nocini PF (2016) The facial grid analysis for filler injection: a cohort study of 300 patients. G Ital Dermatol Venereol 151(5):467–472PubMed
12.
go back to reference Monheit G (2015) Neurotoxins: current concepts in cosmetic use on the face and neck--upper face (glabella, forehead, and Crow’s feet). Plast Reconstr Surg 136(5 Suppl):72S–75SCrossRefPubMed Monheit G (2015) Neurotoxins: current concepts in cosmetic use on the face and neck--upper face (glabella, forehead, and Crow’s feet). Plast Reconstr Surg 136(5 Suppl):72S–75SCrossRefPubMed
13.
go back to reference Raspaldo H, Baspeyras M, Bellity P, Dallara JM, Gassia V, Niforos FR, Belhaouari L (2011) Upper- and mid-face anti-aging treatment and prevention using onabotulinumtoxin A: the 2010 multidisciplinary French consensus--part 1. Consensus Group. J Cosmet Dermatol 10(1):36–50CrossRefPubMed Raspaldo H, Baspeyras M, Bellity P, Dallara JM, Gassia V, Niforos FR, Belhaouari L (2011) Upper- and mid-face anti-aging treatment and prevention using onabotulinumtoxin A: the 2010 multidisciplinary French consensus--part 1. Consensus Group. J Cosmet Dermatol 10(1):36–50CrossRefPubMed
14.
go back to reference Kwon HH, Park HY, Choi SC, Bae Y, Kang C, Jung JY, Park GH (2017) Combined fractional treatment of acne scars involving non-ablative 1,550-nm erbium-glass laser and micro-needling radiofrequency: a 16 week prospective, randomized Split-faceStudy. Acta Derm Venereol 97(8):947–951CrossRefPubMed Kwon HH, Park HY, Choi SC, Bae Y, Kang C, Jung JY, Park GH (2017) Combined fractional treatment of acne scars involving non-ablative 1,550-nm erbium-glass laser and micro-needling radiofrequency: a 16 week prospective, randomized Split-faceStudy. Acta Derm Venereol 97(8):947–951CrossRefPubMed
15.
go back to reference Bencini PL, Tourlaki A, Galimberti M, Pellacani G (2015) Non-ablative fractionated laser skin resurfacing for the treatment of aged neck skin. J Dermatol Treat 26(3):252–256CrossRef Bencini PL, Tourlaki A, Galimberti M, Pellacani G (2015) Non-ablative fractionated laser skin resurfacing for the treatment of aged neck skin. J Dermatol Treat 26(3):252–256CrossRef
16.
go back to reference Raspaldo H, Niforos FR, Gassia V, Dallara JM, Bellity P, Baspeyras M, Belhaouari L (2011) Lower-face and neck antiaging treatment and prevention using onabotulinumtoxin A: the 2010 multidisciplinary French consensus--part 2. Consensus Group. J Cosmet Dermatol 10(2):131–149CrossRefPubMed Raspaldo H, Niforos FR, Gassia V, Dallara JM, Bellity P, Baspeyras M, Belhaouari L (2011) Lower-face and neck antiaging treatment and prevention using onabotulinumtoxin A: the 2010 multidisciplinary French consensus--part 2. Consensus Group. J Cosmet Dermatol 10(2):131–149CrossRefPubMed
17.
go back to reference Lucchese A, Matarese G, Ghislanzoni LH, Gastaldi G, Manuelli M, Gherlone E (2016) Efficacy and effects of palifermin for the treatment of oral mucositis in patients affected by acute lymphoblastic leukemia. Leuk Lymphoma 57(4):820–827CrossRefPubMed Lucchese A, Matarese G, Ghislanzoni LH, Gastaldi G, Manuelli M, Gherlone E (2016) Efficacy and effects of palifermin for the treatment of oral mucositis in patients affected by acute lymphoblastic leukemia. Leuk Lymphoma 57(4):820–827CrossRefPubMed
18.
go back to reference Lucchese A, Matarese G, Manuelli M, Ciuffreda C, Bassani L, Isola G et al (2016) Reliability and efficacy of palifermin in prevention and management of oral mucositis in patients with acute lymphoblastic leukemia: a randomized, double-blind controlled clinical trial. Minerva Stomatol 65(1):43–50PubMed Lucchese A, Matarese G, Manuelli M, Ciuffreda C, Bassani L, Isola G et al (2016) Reliability and efficacy of palifermin in prevention and management of oral mucositis in patients with acute lymphoblastic leukemia: a randomized, double-blind controlled clinical trial. Minerva Stomatol 65(1):43–50PubMed
Metadata
Title
The skin rejuvenation associated treatment—Fraxel laser, Microbotox, and low G prime hyaluronic acid: preliminary results
Authors
Dario Bertossi
Giorgio Giampaoli
Alessandra Lucchese
Maurizio Manuelli
Massimo Albanese
Riccardo Nocini
Pier Francesco Nocini
Publication date
01-09-2019
Publisher
Springer London
Published in
Lasers in Medical Science / Issue 7/2019
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-019-02738-z

Other articles of this Issue 7/2019

Lasers in Medical Science 7/2019 Go to the issue