Published in:
01-01-2012 | Brief Report
Treatment of bisphosphonate-induced osteonecrosis of the jaws with Nd:YAG laser biostimulation
Authors:
Marita Luomanen, Satu Alaluusua
Published in:
Lasers in Medical Science
|
Issue 1/2012
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Excerpt
Bisphosphonates are pharmaceuticals that are increasingly used in the treatment and management of bone disorders like osteoporosis, metabolic bone disease, and bone metastases associated with cancer and multiple myeloma. However, in recent years innumerous cases of necrosis of the jawbone have been documented in patients treated with bisphosphonates and consequently bisphosphonate-induced osteonecrosis of the jaws (ONJ-BP) has been described as a complication secondary to bisphosphonate therapy [
1‐
4]. The risk for bone necrosis has proven to be considerably higher in those cases where bisphosphonates have been given intravenously than per os [
3]. …