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Published in: Neurological Sciences 9/2022

Open Access 01-06-2022 | Hydrocephalus | Review Article

Parkinsonism in idiopathic normal pressure hydrocephalus: is it time for defining a clinical tetrad?

Authors: Giovanni Mostile, Alfonso Fasano, Mario Zappia

Published in: Neurological Sciences | Issue 9/2022

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Abstract

Background

Association between parkinsonism and idiopathic normal pressure hydrocephalus (iNPH) still remains debated. There is already plenty of evidences in the literature suggesting that this clinical sign can be considered as an integral part of the clinical spectrum of iNPH patients.

Methods

We reviewed the possible pitfalls in the core clinical definition of iNPH based on available international diagnostic criteria, phenomenology of parkinsonism in iNPH, and neuroimaging supporting the presence of parkinsonism in iNPH.

Conclusions

We argue that the diagnostic definition of the iNPH “triad” should be possibly reconsidered as a “tetrad” also including parkinsonism.
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Metadata
Title
Parkinsonism in idiopathic normal pressure hydrocephalus: is it time for defining a clinical tetrad?
Authors
Giovanni Mostile
Alfonso Fasano
Mario Zappia
Publication date
01-06-2022
Publisher
Springer International Publishing
Published in
Neurological Sciences / Issue 9/2022
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-022-06119-3

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