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Neurological Sciences
Published in: Neurological Sciences 7/2021

01-07-2021 | Parkinson's Disease | Original Article

Association between subjective autonomic dysfunction and fatigue in Parkinson’s disease in southern Chinese

Authors: Zongbo Zhao, Hui Liu, Jianzhong Xue, Zhige Shi, Nianxing You

Published in: Neurological Sciences | Issue 7/2021

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Abstract

Study objectives

The aim was to investigate the association between autonomic symptoms and fatigue of Parkinson’s disease (PD) in southern Chinese population.

Methods

In this study, 602 PD patients were recruited. All patients were evaluated by Scales for Outcomes in Parkinson’s Disease-Autonomic questionnaire (SCOPA-AUT), Hamilton anxiety rating scale and Hamilton depression rating scale, non-motor symptoms scale (NMSS), and fatigue severity scale (FSS).

Results

Total score and gastrointestinal subpart, urinary subpart, and cardiovascular subpart of NMSS and SCOPA-AUT were associated with FSS scores (NMSS: total score: p < 0.001; gastrointestinal: p = 0.006; urinary: p = 0.001; cardiovascular: p < 0.001; SCOPA-AUT: total score: p < 0.001; gastrointestinal: p = 0.011; urinary: p < 0.001; cardiovascular: p = 0.003).

Conclusions

Autonomic symptoms were associated with fatigue of PD.
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Metadata
Title
Association between subjective autonomic dysfunction and fatigue in Parkinson’s disease in southern Chinese
Authors
Zongbo Zhao
Hui Liu
Jianzhong Xue
Zhige Shi
Nianxing You
Publication date
01-07-2021
Publisher
Springer International Publishing
Published in
Neurological Sciences / Issue 7/2021
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-021-05209-y

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