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Published in: Neurological Sciences 7/2021

01-07-2021 | Deep Brain Stimulation | Brief Communication

Device-aided therapies for advanced Parkinson disease: insights from an international survey

Authors: Luca Marsili, Matteo Bologna, Janis M. Miyasaki, Carlo Colosimo

Published in: Neurological Sciences | Issue 7/2021

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Abstract

Purpose

In the advanced stage of Parkinson disease (PD), therapeutic interventions include device-aided therapies such as continuous subcutaneous apomorphine infusion (CSAI), levodopa-carbidopa intestinal gel (LCIG) infusion, and deep brain stimulation (DBS). Recent evidence has underlined the general lack of randomized, blinded, head-to-head studies on device-aided therapies for advanced PD.

Methods

To better clarify the real-world attitude of clinicians on this matter, we conducted an international survey of forty-four experienced movement disorder specialists regarding the management of device-aided therapies in advanced PD.

Results

Our international survey showed a general agreement that nowadays, motor complications are less common compared to the past (59% agreement), that guidelines to identify candidates for device-aided therapies are currently lacking (57% agreement), and that device-aided therapies will have increased demand in the future (75% agreement).

Conclusions

We conclude that guidelines to assist clinicians and patients to choose device-aided therapies are required.
Literature
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go back to reference Colosimo C, Marsili L (2015) Treatment of Parkinson’s disease. In: Colosimo C, Gil-Nagel A, Gilhus NE, Rapoport A, Williams O (eds) Handbook of neurological therapy. Oxford University Press, New York, pp 293–306 Colosimo C, Marsili L (2015) Treatment of Parkinson’s disease. In: Colosimo C, Gil-Nagel A, Gilhus NE, Rapoport A, Williams O (eds) Handbook of neurological therapy. Oxford University Press, New York, pp 293–306
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go back to reference Marsili L, Vizcarra JA, Sturchio A, Dwivedi AK, Keeling EG, Patel D, Mishra M, Farooqi A, Merola A, Fasano A, Mata IF, Kauffman MA, Espay AJ (2020) When does postural instability appear in monogenic parkinsonisms? An individual-patient meta-analysis. J Neurol. https://doi.org/10.1007/s00415-020-09892-3 Marsili L, Vizcarra JA, Sturchio A, Dwivedi AK, Keeling EG, Patel D, Mishra M, Farooqi A, Merola A, Fasano A, Mata IF, Kauffman MA, Espay AJ (2020) When does postural instability appear in monogenic parkinsonisms? An individual-patient meta-analysis. J Neurol. https://​doi.​org/​10.​1007/​s00415-020-09892-3
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Metadata
Title
Device-aided therapies for advanced Parkinson disease: insights from an international survey
Authors
Luca Marsili
Matteo Bologna
Janis M. Miyasaki
Carlo Colosimo
Publication date
01-07-2021
Publisher
Springer International Publishing
Published in
Neurological Sciences / Issue 7/2021
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-021-05106-4

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