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Open Access 01-04-2020 | Multiple Sclerosis | Review Article

An “all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases

Authors: Marco Salvetti, Mario A. Battaglia, Massimiliano Di Filippo, Gian Luigi Mancardi, Michelangelo Mancuso, Francesco Patti, Maria Pia Sormani, Paola Zaratin

Published in: Neurological Sciences | Issue 4/2020

Abstract

The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and from an analysis of scientific resources in Italy, we here explain why our country may represent an appropriate environment for such actions. Furthermore, we sketch operational framework and business model to be applied in order to accelerate, in parallel, the development of therapies in common and rare diseases.

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Title: An “all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases
Authors: Marco Salvetti
Mario A. Battaglia
Massimiliano Di Filippo
Gian Luigi Mancardi
Michelangelo Mancuso
Francesco Patti
Maria Pia Sormani
Paola Zaratin
Publication date: 01-04-2020
Publisher: Springer International Publishing
Keyword: Multiple Sclerosis
Published in: Neurological Sciences / Issue 4/2020
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-019-04189-4

At a glance: The STEP trials

Springer Medicine

An “all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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