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Published in: Neurological Sciences 11/2019

01-11-2019 | Multiple Sclerosis | Review Article

Exploring the role of music therapy in multiple sclerosis: brief updates from research to clinical practice

Authors: Claudia Vinciguerra, Nicola De Stefano, Antonio Federico

Published in: Neurological Sciences | Issue 11/2019

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Abstract

Background

Physical, cognitive and mood-behavioral disturbances are very common in people with multiple sclerosis (MS) representing a relevant disease burden. Recently, in this field, several studies investigated the role of music therapy (MT) as a complementary therapeutic approach especially in terms of rehabilitation strategy.

Objectives

The aim of this review is to report and discuss the effectiveness of various music-based interventions (MBIs) for clinical outcomes in MS patients.

Data sources

All English medical papers registered in the Web of Knowledge, PubMed, Google Scholar, and ScienceDirect from March 1999 to March 2019.

Inclusion and exclusion criteria

We selected all the articles concerning MBIs in MS including papers that dealt with human samples and excluding non-human samples, reviews and case reports.

Results

Out of 46 articles, we selected 24 papers of which 13 completely following the inclusion criteria were evaluated for the present analysis.

Discussion

We explored the efficacy of several MT programs, taking into account the different aspects of application feasibility in the clinical management of MS patients and the future challenges.
Literature
1.
go back to reference Comi G, Radaelli M, Sorensen SP (2017) Evolving concepts in the treatment of relapsing remitting multiple sclerosis. Lancet 389:1347–1356CrossRef Comi G, Radaelli M, Sorensen SP (2017) Evolving concepts in the treatment of relapsing remitting multiple sclerosis. Lancet 389:1347–1356CrossRef
2.
go back to reference Sihvonen AJ, Sarkamo T, Leo V et al (2017) Music-based interventions in neurological rehabilitation. Lancet Neurol 16:648–660CrossRef Sihvonen AJ, Sarkamo T, Leo V et al (2017) Music-based interventions in neurological rehabilitation. Lancet Neurol 16:648–660CrossRef
3.
go back to reference Moumdjian L, Sarkamo T, Leone C, Leman M, Feys P (2017) Effectiveness of music- based interventions on motoricity or cognitive functioning in neurological populations: a systematic review. Eur J Phys Rehabil Med 53(3):466–482 Moumdjian L, Sarkamo T, Leone C, Leman M, Feys P (2017) Effectiveness of music- based interventions on motoricity or cognitive functioning in neurological populations: a systematic review. Eur J Phys Rehabil Med 53(3):466–482
4.
go back to reference Raglio A, Attardo L, Gontero G et al (2015) Effects of music therapy on mood in neurological patients. Worl J Psychiatr 5:68–79CrossRef Raglio A, Attardo L, Gontero G et al (2015) Effects of music therapy on mood in neurological patients. Worl J Psychiatr 5:68–79CrossRef
5.
go back to reference Ostermann T, Schmid W (2006) Music therapy in the treatment of multiple sclerosis: a comprehensive literature review. Expert Rev Neurother 6:469–477CrossRef Ostermann T, Schmid W (2006) Music therapy in the treatment of multiple sclerosis: a comprehensive literature review. Expert Rev Neurother 6:469–477CrossRef
6.
go back to reference Vinciguerra C (2017) Music intervention efficacy in elderly: a promising non-pharmacological approach to cognitive dysfunctions. Neurol Sci 38:933–934CrossRef Vinciguerra C (2017) Music intervention efficacy in elderly: a promising non-pharmacological approach to cognitive dysfunctions. Neurol Sci 38:933–934CrossRef
7.
go back to reference Altenmüller E, Marco-Pallares J, Münte TF, Schneider S (2009) Neural reorganization underlies improvement in stroke-induced motor dysfunction by music-supported therapy. Ann N Y Acad Sci 1169:395–405CrossRef Altenmüller E, Marco-Pallares J, Münte TF, Schneider S (2009) Neural reorganization underlies improvement in stroke-induced motor dysfunction by music-supported therapy. Ann N Y Acad Sci 1169:395–405CrossRef
8.
go back to reference Hsu MH, Flowerdew R, Parker M, Fachner J, Odell-Miller H (2015) Individual music therapy for managing neuropsychiatric symptoms for people with dementia and their carers: a cluster randomized controlled feasibility study. BMC Geriatr 15:84CrossRef Hsu MH, Flowerdew R, Parker M, Fachner J, Odell-Miller H (2015) Individual music therapy for managing neuropsychiatric symptoms for people with dementia and their carers: a cluster randomized controlled feasibility study. BMC Geriatr 15:84CrossRef
9.
go back to reference Chu H, Yang CY, Lin Y et al (2014) The impact of group music therapy on depression and cognition in elderly persons with dementia: a randomized controlled study. Biol Res Nurs 16:209–217CrossRef Chu H, Yang CY, Lin Y et al (2014) The impact of group music therapy on depression and cognition in elderly persons with dementia: a randomized controlled study. Biol Res Nurs 16:209–217CrossRef
11.
go back to reference Seebacher B, Kuisma R, Glynn A, Berger T (2017) The effect of rhythmic-cued motor imagery on walking, fatigue and quality of life in people with multiple sclerosis: a randomised controlled trial. Mult Scler J 23:286–296CrossRef Seebacher B, Kuisma R, Glynn A, Berger T (2017) The effect of rhythmic-cued motor imagery on walking, fatigue and quality of life in people with multiple sclerosis: a randomised controlled trial. Mult Scler J 23:286–296CrossRef
14.
go back to reference Conklyn D, Stough D, Novak E (2010) A home-based walking program using rhythmic auditory stimulation improves gait performance in patients with multiple sclerosis: a pilot study. Neurorehabil Neural Repair 24:835–842CrossRef Conklyn D, Stough D, Novak E (2010) A home-based walking program using rhythmic auditory stimulation improves gait performance in patients with multiple sclerosis: a pilot study. Neurorehabil Neural Repair 24:835–842CrossRef
15.
go back to reference Charlton ME, Gabriel KP, Munsinger T (2010) Program evaluation results of a structured group exercise program in individual with multiple sclerosis. Int J MS Care 12:92–96CrossRef Charlton ME, Gabriel KP, Munsinger T (2010) Program evaluation results of a structured group exercise program in individual with multiple sclerosis. Int J MS Care 12:92–96CrossRef
16.
go back to reference Moore KS et al (2008) The effectiveness of music as a mnemonic device on recognition memory for people with multiple sclerosis. J Music Ther 45:307–329CrossRef Moore KS et al (2008) The effectiveness of music as a mnemonic device on recognition memory for people with multiple sclerosis. J Music Ther 45:307–329CrossRef
17.
go back to reference Aldridge D, Schmid W, Kaeder M et al (2005) Functionality or aesthetics? A pilot study of music therapy in the treatment of multiple sclerosis patients. Complementary Therapies in Medicine 13:25–33CrossRef Aldridge D, Schmid W, Kaeder M et al (2005) Functionality or aesthetics? A pilot study of music therapy in the treatment of multiple sclerosis patients. Complementary Therapies in Medicine 13:25–33CrossRef
18.
go back to reference Wiens M, Reimer M, Guyn H (1999) Music therapy as a treatment method for improving respiratory muscle strength in patients with advanced multiple sclerosis a pilot study. Rehabil Nurs 24:74–80CrossRef Wiens M, Reimer M, Guyn H (1999) Music therapy as a treatment method for improving respiratory muscle strength in patients with advanced multiple sclerosis a pilot study. Rehabil Nurs 24:74–80CrossRef
19.
go back to reference Baram Y, Miller A (2007) Auditory feedback control for improvement of gait in patients with multiple sclerosis. J Neurol Sci 254:90–94CrossRef Baram Y, Miller A (2007) Auditory feedback control for improvement of gait in patients with multiple sclerosis. J Neurol Sci 254:90–94CrossRef
20.
go back to reference Grahn JA, Brett M (2007) Rhythm and beat perception in motor areas of the brain. J Cogn Neurosci 19:893–906CrossRef Grahn JA, Brett M (2007) Rhythm and beat perception in motor areas of the brain. J Cogn Neurosci 19:893–906CrossRef
21.
go back to reference Gatti R, Tettamanti A, Lambiase S, Rossi P, Comola M (2015) Improving hand functional use in subjects with multiple sclerosis using a musical keyboard: a randomized controlled trial. Physiother Res Int 20:100–107CrossRef Gatti R, Tettamanti A, Lambiase S, Rossi P, Comola M (2015) Improving hand functional use in subjects with multiple sclerosis using a musical keyboard: a randomized controlled trial. Physiother Res Int 20:100–107CrossRef
22.
go back to reference Penta M, Tesio L, Arnould C, Zancan A, Thonnard JL (2001) The ABILHAND questionnaire as a measure of manual ability in chronic stroke patients: Rasch-based validation and relationship to upper limb impairment. Stroke 32:1627–1634CrossRef Penta M, Tesio L, Arnould C, Zancan A, Thonnard JL (2001) The ABILHAND questionnaire as a measure of manual ability in chronic stroke patients: Rasch-based validation and relationship to upper limb impairment. Stroke 32:1627–1634CrossRef
23.
go back to reference Young HJ, Mehta TS, Herman C, Wang F, Rimmer JH (2019) The effects of M2M and adapted yoga on physical and psychosocial outcomes in people with multiple sclerosis. Arch Phys Med Rehabil 100:391–400CrossRef Young HJ, Mehta TS, Herman C, Wang F, Rimmer JH (2019) The effects of M2M and adapted yoga on physical and psychosocial outcomes in people with multiple sclerosis. Arch Phys Med Rehabil 100:391–400CrossRef
24.
go back to reference Mandelbaum R, Triche EW, Fasoli SE, Lo AC (2015) A pilot study : examining the effects and tolerability of structured dance intervention for individuals with multiple sclerosis. Disabil Rehabil 38:218–222CrossRef Mandelbaum R, Triche EW, Fasoli SE, Lo AC (2015) A pilot study : examining the effects and tolerability of structured dance intervention for individuals with multiple sclerosis. Disabil Rehabil 38:218–222CrossRef
25.
go back to reference Peterson DA, Thaut MH (2002) Delay modulates spectral correlates in the human EEG of non-verbal auditory working memory. Neurosci Lett 328:17–20CrossRef Peterson DA, Thaut MH (2002) Delay modulates spectral correlates in the human EEG of non-verbal auditory working memory. Neurosci Lett 328:17–20CrossRef
26.
go back to reference DA Thaut P, McIntosh GC (2005) Temporal entrainment of cognitive functions. Musical mnemonics induce brain plasticity and oscillatory synchrony in neural networks underlying memory. Ann N Y Acad Sci 1060:243–254CrossRef DA Thaut P, McIntosh GC (2005) Temporal entrainment of cognitive functions. Musical mnemonics induce brain plasticity and oscillatory synchrony in neural networks underlying memory. Ann N Y Acad Sci 1060:243–254CrossRef
27.
go back to reference Schimdt W, Aldridge D (2004) Active music therapy in the treatment of multiple sclerosis patients: a matched control study. J Music Ther 41:225–240CrossRef Schimdt W, Aldridge D (2004) Active music therapy in the treatment of multiple sclerosis patients: a matched control study. J Music Ther 41:225–240CrossRef
28.
go back to reference O’Callaghan C (1999) Lyrical themes in songs written by palliative care patients. Music therapy in palliative care: new voices. Aldridge D. Jessica Kingsley Publishers, London, 43–58 O’Callaghan C (1999) Lyrical themes in songs written by palliative care patients. Music therapy in palliative care: new voices. Aldridge D. Jessica Kingsley Publishers, London, 43–58
29.
go back to reference Gilberston R, Maryanna KD (2017) Mindfulness in motion for people with multiple sclerosis: a feasibility study. Int J MS Care 19:225–231CrossRef Gilberston R, Maryanna KD (2017) Mindfulness in motion for people with multiple sclerosis: a feasibility study. Int J MS Care 19:225–231CrossRef
31.
go back to reference Molinari M, Leggio MG, De Martin M et al (2003) The neurobiology of rhythmic motor entrainment. Ann N Y Acad Sci 999:313–321CrossRef Molinari M, Leggio MG, De Martin M et al (2003) The neurobiology of rhythmic motor entrainment. Ann N Y Acad Sci 999:313–321CrossRef
33.
go back to reference Meyer M, Elmer S, Baumann S et al (2007) Short-term plasticity in the auditory system: differential neural responses to perception and imagery of speech and music. Restor Neurol Neurosci 25:411–431PubMed Meyer M, Elmer S, Baumann S et al (2007) Short-term plasticity in the auditory system: differential neural responses to perception and imagery of speech and music. Restor Neurol Neurosci 25:411–431PubMed
34.
go back to reference Bangert M, Peschel T, Schlaug G, Rotte M, Drescher D, Hinrichs H, Heinze HJ, Altenmüller E (2006) Shared networks for auditory and motor processing in professional pianists: evidence from fMRI conjunction. Neuroimage. 30:917–926CrossRef Bangert M, Peschel T, Schlaug G, Rotte M, Drescher D, Hinrichs H, Heinze HJ, Altenmüller E (2006) Shared networks for auditory and motor processing in professional pianists: evidence from fMRI conjunction. Neuroimage. 30:917–926CrossRef
35.
go back to reference DeDrew MJ, van der Wilk AS, Poppe E et al (2012) Rehabilitation, exercise therapy and music in patients with Parkinson’s disease: a meta-analysis of the effects of music-based movement therapy on walking ability, balance, and quality of life. Parkinsonism Relat Disord 18:114–119 DeDrew MJ, van der Wilk AS, Poppe E et al (2012) Rehabilitation, exercise therapy and music in patients with Parkinson’s disease: a meta-analysis of the effects of music-based movement therapy on walking ability, balance, and quality of life. Parkinsonism Relat Disord 18:114–119
36.
go back to reference Sarkamo T, Tervaniemi M, Latinem S et al (2008) Music listening enhances cognitive recovery and mood after middle cerebral artery stroke. Brain 13:866–876CrossRef Sarkamo T, Tervaniemi M, Latinem S et al (2008) Music listening enhances cognitive recovery and mood after middle cerebral artery stroke. Brain 13:866–876CrossRef
37.
go back to reference Thau M, Leins AK, Rice RR et al (2007) Rhythmic auditory stimulation improves gait more than NDT/Bobath training in near-ambulatory patients early poststroke: a single blind randomized trial. Neurorehabil Neural Repair 21:455–459CrossRef Thau M, Leins AK, Rice RR et al (2007) Rhythmic auditory stimulation improves gait more than NDT/Bobath training in near-ambulatory patients early poststroke: a single blind randomized trial. Neurorehabil Neural Repair 21:455–459CrossRef
38.
go back to reference Rojo N, Amenqual J, Juncadella et al (2011) Music-supported arm training induces plasticity in the sensorimotor cortex in chronic stroke. Brain Inj 25:787–793CrossRef Rojo N, Amenqual J, Juncadella et al (2011) Music-supported arm training induces plasticity in the sensorimotor cortex in chronic stroke. Brain Inj 25:787–793CrossRef
39.
go back to reference Luft AR, McCombe-Waller S, Whitall J, Forrester LW, Macko R, Sorkin JD, Schulz JB, Goldberg AP, Hanley DF (2004) Repetitive bilateral arm training and motor cortex activation in chronic stroke. JAMA. 292:1853–1861CrossRef Luft AR, McCombe-Waller S, Whitall J, Forrester LW, Macko R, Sorkin JD, Schulz JB, Goldberg AP, Hanley DF (2004) Repetitive bilateral arm training and motor cortex activation in chronic stroke. JAMA. 292:1853–1861CrossRef
41.
go back to reference Pallison J, Roussel-Baclet C, Maillet D et al (2015) Music enhances verbal episodic memory in Alzheimer’s disease. J Clin Exp Neuropsychol 37:503–517CrossRef Pallison J, Roussel-Baclet C, Maillet D et al (2015) Music enhances verbal episodic memory in Alzheimer’s disease. J Clin Exp Neuropsychol 37:503–517CrossRef
42.
go back to reference Chiaravalloti ND, DeLuca J (2008) Cognitive impairment in multiple sclerosis. Lancet Neurol 7:1139–1151CrossRef Chiaravalloti ND, DeLuca J (2008) Cognitive impairment in multiple sclerosis. Lancet Neurol 7:1139–1151CrossRef
43.
go back to reference Tscahcher W, Schildt M, Sander K (2010) Brain connectivity in listening to affective stimuli: a functional magnetic resonance imaging (fMRI) study and implications for psychotherapy. Psychother Res 20:576–588CrossRef Tscahcher W, Schildt M, Sander K (2010) Brain connectivity in listening to affective stimuli: a functional magnetic resonance imaging (fMRI) study and implications for psychotherapy. Psychother Res 20:576–588CrossRef
44.
go back to reference Salimpoor VN, Benovoy M, Larcher K et al (2011) Anatomically distinct dopamine release during anticipation and experience of peak emotion to music. Nat Neurosci 4:257–262CrossRef Salimpoor VN, Benovoy M, Larcher K et al (2011) Anatomically distinct dopamine release during anticipation and experience of peak emotion to music. Nat Neurosci 4:257–262CrossRef
45.
go back to reference Okada K, Kurita A, Takase B et al Effects of music therapy on autonomic nervous system activity, incidence of heart failure events, and plasma cytokine and catecholamine levels in elderly patient with cerebrovascular diseases and dementia. Int Heart J 50:95–110CrossRef Okada K, Kurita A, Takase B et al Effects of music therapy on autonomic nervous system activity, incidence of heart failure events, and plasma cytokine and catecholamine levels in elderly patient with cerebrovascular diseases and dementia. Int Heart J 50:95–110CrossRef
46.
go back to reference McCaffrey T, Edwards J (2016) Music therapy helped me get back doing: perspectives of music therapy participants in mental health services. J Music Ther 53(2):121–148CrossRef McCaffrey T, Edwards J (2016) Music therapy helped me get back doing: perspectives of music therapy participants in mental health services. J Music Ther 53(2):121–148CrossRef
Metadata
Title
Exploring the role of music therapy in multiple sclerosis: brief updates from research to clinical practice
Authors
Claudia Vinciguerra
Nicola De Stefano
Antonio Federico
Publication date
01-11-2019
Publisher
Springer International Publishing
Published in
Neurological Sciences / Issue 11/2019
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-019-04007-x

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