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Neurological Sciences
Published in: Neurological Sciences 7/2019

01-07-2019 | Dystonia | Brief Communication

Lack of inter-muscular coherence of axial muscles in Pisa syndrome

Authors: Emanuela Formaggio, Stefano Masiero, Daniele Volpe, Elena Demertzis, Laura Gallo, Alessandra Del Felice

Published in: Neurological Sciences | Issue 7/2019

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Abstract

Background

Pisa syndrome is a lateral deviation of the trunk described in Parkinson’s disease (PD). Its etiology is still unknown; advanced muscular signal analysis techniques, such as inter-muscular coherence, could help clarifying its pathophysiology and suggest therapeutic strategies.

Methods

Fourteen idiopathic PD subjects with a lateral deviation of the trunk of at least 10° were included. Electromyographic (EMG) signal was recorded from bilateral thoracic, and lumbar para-spinal and obliqui externi muscles. The synchronization between EMG right and left side signals was quantified using the magnitude-squared coherence function.

Results

In our sample, coherence (range 0–1) did not exceed 0.3, which indicates a lack of intra-muscular coherence.

Conclusion

This finding is suggestive of a defective muscular fine-tuning, which has been associated with bradykinesia. These data support the hypothesis of PS as a clinical sign of bradykinesia, impacting on therapeutic and rehabilitative options.
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Metadata
Title
Lack of inter-muscular coherence of axial muscles in Pisa syndrome
Authors
Emanuela Formaggio
Stefano Masiero
Daniele Volpe
Elena Demertzis
Laura Gallo
Alessandra Del Felice
Publication date
01-07-2019
Publisher
Springer International Publishing
Published in
Neurological Sciences / Issue 7/2019
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-019-03821-7

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