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01-06-2019 | Influenza | Letter to the Editor

Malignant syndrome triggered by influenza A virus infection in a patient with Parkinson’s disease with improvement after intravenous peramivir treatment

Authors: Kosuke Matsuzono, Masamichi Baba, Goro Imai, Hiroaki Imai, Shigeru Fujimoto

Published in: Neurological Sciences | Issue 6/2019

Excerpt

Malignant syndrome, also called parkinsonism-hyperpyrexia syndrome, is a rare medical emergency in patients with Parkinson’s disease (PD). The precipitating events that trigger malignant syndrome in patients with PD are anti-parkinsonian drug withdrawal and stress-related factors [1, 2]. Infection is a major cause of malignant syndrome, and fever is considered the trigger [1]. However, the relationship among malignant syndrome, influenza virus infection, and treatment for influenza virus remains unclear. We herein report a case involving a man with PD who developed malignant syndrome secondary to influenza A virus infection but improved after intravenous peramivir treatment without dantrolene. …

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Title: Malignant syndrome triggered by influenza A virus infection in a patient with Parkinson’s disease with improvement after intravenous peramivir treatment
Authors: Kosuke Matsuzono
Masamichi Baba
Goro Imai
Hiroaki Imai
Shigeru Fujimoto
Publication date: 01-06-2019
Publisher: Springer International Publishing
Keywords: Influenza
Parkinson's Disease
Benserazide
Levodopa
Bromocriptine
Pramipexole
Apomorphine
Dantrolene
Published in: Neurological Sciences / Issue 6/2019
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-018-3696-4

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