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Neurological Sciences
Published in: Neurological Sciences 11/2018

01-11-2018 | Brief Communication

Anti-GABAB receptor encephalitis in a patient with gastric adenocarcinoma

Authors: Xiao-Tao Jia, Yanfang Pan, Zhengli Di, Naibing Gu, Zhiqin Liu, Yu-Ming Kang

Published in: Neurological Sciences | Issue 11/2018

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Abstract

Anti-γ-aminobutyric acid-B (GABAB) receptor encephalitis is an autoimmune encephalitis associated with antibodies against neuronal cell surface antigens, which are primarily observed with small-cell lung cancer, melanoma, and thymoma. Here, we first report a case on the association between a relatively frequent cancer, gastric adenocarcinoma (GAC), and a rare GABAB receptor antibody limbic encephalitis. The patient was treated with immunotherapy and combined-drug chemotherapy, which were partially effective in terms of stabilizing the tumor and relieving neurological symptoms. This report indicates that, when patients present with GABAB receptor antibody limbic encephalitis, regular and broad screening for tumors including gastric adenocarcinoma should also be considered.
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Metadata
Title
Anti-GABAB receptor encephalitis in a patient with gastric adenocarcinoma
Authors
Xiao-Tao Jia
Yanfang Pan
Zhengli Di
Naibing Gu
Zhiqin Liu
Yu-Ming Kang
Publication date
01-11-2018
Publisher
Springer Milan
Published in
Neurological Sciences / Issue 11/2018
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-018-3536-6

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