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Neurological Sciences
Published in: Neurological Sciences 11/2013

01-11-2013 | Letter to the Editor

Serial MRI findings in brain anoxia leading to Lance–Adams syndrome: a case report

Authors: Edoardo Ferlazzo, Sara Gasparini, Vittoria Cianci, Andrea Cherubini, Umberto Aguglia

Published in: Neurological Sciences | Issue 11/2013

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Abstract

Although in literature almost 150 patients with Lance-Adams Syndrome (LAS) have been reported, neuroradiological evaluations were often performed in late stages and there is no serial study evaluating LAS from early stages. We herein report a serial neuroimaging study demonstrating early and transient involvement of cerebellum and thalami in a LAS patient. We may hypothesize that a transient cerebral hypoxia provoked a permanent synaptic rearrangements of the neuronal networks involved in the pathogenesis of post-hypoxic myoclonus in our patient.
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Ferlazzo E, Gasparini S, Gambardella A, Labate A, Cianci V, Cherubini A, Lanza P, Quattrone A, Aguglia U (2012) Unilateral basal ganglia atrophy in a patient with tuberous sclerosis complex and hemichorea. Mov Disord 27:458–460PubMedCrossRef
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Werhahn KJ, Brown P, Thompson PD, Marsden CD (1997) The clinical features and prognosis of chronic posthypoxic myoclonus. Mov Disord 12:216–220PubMedCrossRef
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Zhang YX, Liu JR, Jiang B, Liu HQ, Ding MP, Song SJ, Zhang BR, Zhang H, Xu B, Chen HH, Wang ZJ, Huang JZ (2007) Lance–Adams syndrome: a report of two cases. J Zhejiang Univ Sci B 8:715–720PubMedCrossRef
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Metadata
Title
Serial MRI findings in brain anoxia leading to Lance–Adams syndrome: a case report
Authors
Edoardo Ferlazzo
Sara Gasparini
Vittoria Cianci
Andrea Cherubini
Umberto Aguglia
Publication date
01-11-2013
Publisher
Springer Milan
Published in
Neurological Sciences / Issue 11/2013
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-013-1356-2

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