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Neurological Sciences
Published in: Neurological Sciences 1/2011

01-05-2011 | Brief Communication

Interictal cortical reorganization in episodic migraine without aura: an event-related fMRI study during parametric trigeminal nociceptive stimulation

Authors: A. Tessitore, A. Russo, F. Esposito, A. Giordano, G. Taglialatela, R. De Micco, M. Cirillo, F. Conte, F. d’Onofrio, S. Cirillo, Gioacchino Tedeschi

Published in: Neurological Sciences | Special Issue 1/2011

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Abstract

The aim of our study was to explore the pain processing network in patients with migraine during trigeminal nociceptive stimulation. Sixteen patients with episodic migraine without aura and 16 healthy controls performed functional magnetic resonance imaging during thermal stimuli (at 41, 51 and 53°C). Patients with migraine showed a greater activation in the perigenual part of anterior cingulate cortex at 51°C and less activation in the bilateral somatosensory cortex at 53°C compared to healthy controls. There were no differences in experimental pain perception between groups. Our findings demonstrate a functional reorganization of cerebral areas known to be involved in pain processing in patients with migraine.
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Metadata
Title
Interictal cortical reorganization in episodic migraine without aura: an event-related fMRI study during parametric trigeminal nociceptive stimulation
Authors
A. Tessitore
A. Russo
F. Esposito
A. Giordano
G. Taglialatela
R. De Micco
M. Cirillo
F. Conte
F. d’Onofrio
S. Cirillo
Gioacchino Tedeschi
Publication date
01-05-2011
Publisher
Springer Milan
Published in
Neurological Sciences / Issue Special Issue 1/2011
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-011-0537-0

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