Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Hernia
Published in: Hernia 4/2017

01-08-2017 | Original Article

Tackers versus glue mesh fixation: an objective assessment of postoperative acute and chronic pain using inflammatory markers

Authors: W. Liew, Y. Y. Wai, N. R. Kosai, H. S. Gendeh

Published in: Hernia | Issue 4/2017

Login to get access

Abstract

Purpose

Laparoscopic hernioplasty has become a popular choice for inguinal hernia repair since its advent in 1990s. Postoperative pain is an undesirable clinical outcome impairing daily activity of 22.5% of patients. The aim of this study is to evaluate postoperative acute and chronic pain via inflammatory markers as an objective assessment following tacks or glue mesh fixation in TEP repair.

Methods

Sixty-six (66) patients with unilateral uncomplicated inguinal hernia were randomized into 34 patients in the tacker and 32 patients in cyanoacrylate glue mesh fixation in TEP repair. The extent of surgical trauma was evaluated by measuring inflammatory markers of C-reactive protein, white blood cell count at 48 h, and ESR at 3 months postoperatively. Postoperative acute and chronic pain was assessed by recording the visual analogue scale scores and surgical complications were recorded over 3 months of the study period.

Results

The median CRP and WBC levels at postoperative 48 h in both groups raised significantly from the baseline values (p < 0.05), however, did not differ significantly between the two study groups at 48 h (p > 0.05). The median ESR level increased significantly at 3 months postoperatively from baseline in the glue mesh fixation group only (p < 0.05), however, did not differ significantly between the two study groups (p > 0.05). There was no significant difference for VAS scores at all timelines between the tacker and glue mesh fixation group (p > 0.05).

Conclusion

Cyanoacrylate glue mesh fixation technique as an alternative method to mechanical fixation in TEP repair is comparable to tacker and can be considered to be safe and feasible.
Literature
1.
Schwab R, Willims A, Kroger A, Becker HP (2006) Less chronic pain following mesh fixation using a fibrin sealant in TEP inguinal hernia repair. Hernia 10(3):272–277CrossRefPubMed
2.
Lovisetto F, Zonta S, Rota E, Mazzilli M, Bardone M, Bottero L, Faillace G, Longoni M (2007) Use of human fibrin glue (Tissucol) versus staples for mesh fixation in laparoscopic transabdominal preperitoneal hernioplasty: a prospective, randomized study. Ann Surg 245(2):222–231CrossRefPubMedPubMedCentral
3.
Olmi S, Scaini A, Erba L, Guaglio M, Croce E (2007) Quantification of pain in laparoscopic transabdominal preperitoneal (TAPP) inguinal hernioplasty identifies marked differences between prosthesis fixation systems. Surgery 142(1):40–46CrossRefPubMed
4.
Kumar S, Wilson RG, Nixon SJ, Macintyre IMC (2002) Chronic pain after laparoscopic and open mesh repair of groin hernia. Br J Surg 89(11):1476–1479CrossRefPubMed
5.
Ali SM, Zendejas B, Yadav S, Hernandez-Irizarry RC, Lohse CM, Farley DR (2013) Predictors of chronic groin discomfort after laparoscopic totally extraperitoneal inguinal hernia repair. J Am Coll Surg 217(1):72–80CrossRefPubMed
6.
Burgmans JP, Schouten N, Clevers GJ, Verleisdonk EJ, Davids PH, Voorbrood CE, Simmermacher RK, Van Dalen T (2015) Pain after totally extraperitoneal (TEP) hernia repair might fade out within a year. Hernia 19(4):579–585CrossRefPubMed
7.
Topart P, Vandenbroucke F, Lozac’h P (2005) Tisseel vs tack staples as mesh fixation in totally extraperitoneal laparoscopic repair of groin hernias. Surg Endosc 19(5):724–727CrossRefPubMed
8.
Ceccarelli G, Casciola L, Pisanelli MC, Bartoli A, Di Zitti L, Spaziani A, Biancafarina A, Stefanoni M, Patriti A (2008) Comparing fibrin sealant with staples for mesh fixation in laparoscopic transabdominal hernia repair: a case control-study. Surg Endosc 22(3):668–673CrossRefPubMed
9.
Pramod T (2009) Shinde. Fibrin sealant versus use of tackers for fixation of mesh in laparoscopic inguinal hernia repair. World J Laparosc Surg 2(1):42–48
10.
Jourdan IC, Bailey ME (1998) Initial experience with the use of N-butyl 2-cyanoacrylate glue for the fixation of polypropylene mesh in laparoscopic hernia repair. Surg Laparosc Endosc 8(4):291–293CrossRefPubMed
11.
Kukleta JF, Freytag C, Weber M (2012) Efficiency and safety of mesh fixation in laparoscopic inguinal hernia repair using n-butyl cyanoacrylate: long term biocompatibility in over 1300 mesh fixations. Hernia 16(2):153–162CrossRefPubMed
12.
Nowobilski W, Dobosz M, Wojciechowicz T, Mionskowska L (2004) Lichtenstein inguinal hernioplasty using butyl-2-cyanoacrylate versus sutures: preliminary experience of a prospective randomized trial. Eur Surg Res 36(6):367–370CrossRefPubMed
13.
Helbling C, Schlumpf R (2003) Sutureless Lichtenstein: first results of a prospective randomised clinical trial. Hernia 7(2):80–84CrossRefPubMed
14.
Akhtar K, Kamalky-asl ID, Lamb WR, Laing I, Walton L, Pearson RC, Parrott NR (1998) Metabolic and inflammatory responses after laparoscopic and open inguinal hernia repair. Ann R Coll Surg Engl 80(2):125–130PubMedPubMedCentral
15.
Suter M, Martinet O, Spertini F (2002) Reduced acute phase response after laparoscopic total extraperitoneal bilateral hernia repair compared to open repair with the Stoppa procedure. Surg Endosc 16(8):1214–1219CrossRefPubMed
16.
Uzunkoy A, Coskun A, Akıncı OF, Kocyigit A (2000) Systemic stress responses after laparoscopic or open hernia repair. Eur J Surg 166(6):467–471CrossRefPubMed
17.
Rahr HB, Bendix J, Ahlburg P, Gjedsted J, Funch-Jensen P, Tønnesen E (2006) Coagulation, inflammatory, and stress responses in a randomized comparison of open and laparoscopic repair of recurrent inguinal hernia. Surg Endosc 20(3):468–472CrossRefPubMed
18.
Hanswijck Van, de Jonge P, Lloyd A, Horsfall L, Tan R, O’Dwyer PJ (2000) The measurement of chronic pain and health-related quality of life following inguinal hernia repair: a review of the literature. Hernia 12(6):561–569CrossRef
19.
Kaul A, Hutfless S, Le H, Hamed SA, Le H, Nguyen KTH, Michael RM (2012) Staple versus fibrin glue fixation in laparoscopic total extraperitoneal repair of inguinal hernia: a systematic review and meta-analysis. Surg Endosc 26(5):1269–1278CrossRefPubMed
20.
Gunal O, Ozer S, Gürleyik E, Bahçebaşi T (2007) Does the approach to the groin make a difference in hernia repair? Hernia 11(5):429–434CrossRefPubMed
21.
Gurleyik E, Gurleyik G, Cetinkaya F, Unalmiser S (1998) The inflammatory response to open tension-free inguinal hernioplasty versus conventional repairs. Am J Surg 175(3):179–182CrossRefPubMed
22.
Larsson S, Thelander U, Friberg S (1992) C-reactive protein (CRP) levels after elective orthopedic surgery. Clin Orthop Relat Res 275:237–242
23.
Husain Tarik M, Kim David H (2002) C-reactive protein and erythrocyte sedimentation rate in orthopaedics. Univ Pennsylv Ortho J 15:13–16
24.
Dhankhar Devi S, Sharma Naveen, Mishra Tushar, Kaur Navneet, Singh Seema, Gupta Sanjay (2014) Totally extraperitoneal repair under general anesthesia versus Lichtenstein repair under local anesthesia for unilateral inguinal hernia: a prospective randomized controlled trial. Surg Endosc 28(3):996–1002CrossRefPubMed
25.
Lau H (2005) Fibrin sealant versus mechanical stapling for mesh fixation during endoscopic extraperitoneal inguinal hernioplasty: a randomized prospective trial. Ann Surg 242(5):670–675CrossRefPubMedPubMedCentral
Metadata
Title
Tackers versus glue mesh fixation: an objective assessment of postoperative acute and chronic pain using inflammatory markers
Authors
W. Liew
Y. Y. Wai
N. R. Kosai
H. S. Gendeh
Publication date
01-08-2017
Publisher
Springer Paris
Published in
Hernia / Issue 4/2017
Print ISSN: 1265-4906
Electronic ISSN: 1248-9204
DOI
https://doi.org/10.1007/s10029-017-1611-1

Other articles of this Issue 4/2017

Hernia 4/2017 Go to the issue

Original Article

The effect of chronic constipation on the development of inguinal herniation

Comment

Reply to comment to: Recurrence mechanisms after inguinal hernia repair by the Onstep technique: a case series

Original Article

Hernia repair with polypropylene mesh is not associated with an increased risk of autoimmune disease in adult men

Original Article

Crura augmentation with Bio-A® mesh for laparoscopic repair of hiatal hernia: single-institution experience with 100 consecutive patients

Original Article

Advanced glycation end products as a biomarker for incisional hernia

Original Article

Tobacco use is not associated with groin hernia repair, a population-based study