Skip to main content
Top
Published in: Pediatric and Developmental Pathology 1/2005

01-02-2005 | CASE REPORT

“Proximal-type” and Classic Epithelioid Sarcomas Represent a Clinicopathologic Continuum: Case Report

Authors: Dinesh Rakheja, Kathleen S. Wilson, John Meehan, Roger A. Schultz, Ana M. Gomez

Published in: Pediatric and Developmental Pathology | Issue 1/2005

Login to get access

Abstract

We report a case of an epithelioid sarcoma that occurred in the right hand of a 14−year-old boy and had the “proximal-type” morphology and a complex, near-tetraploid karyotype. The tumor metastasized to the lungs, where the morphology was typical for the classic epithelioid sarcoma. Based on the morphologic and cytogenetic findings in this case, we suggest that the proximal-type and the classic epithelioid sarcomas are not distinct entities but represent a continuum.
Literature
1.
go back to reference Barch, MJKnutsen, TSpurbeck, JL eds. 1997The AGT cytogenetics laboratory manual3Raven PressNew York Barch, MJKnutsen, TSpurbeck, JL eds. 1997The AGT cytogenetics laboratory manual3Raven PressNew York
2.
go back to reference Mitelman, F eds. 1995An international system for human cytogenetic nomenclatureS. KargerBasel Mitelman, F eds. 1995An international system for human cytogenetic nomenclatureS. KargerBasel
3.
go back to reference Enzinger, FM 1970Epithelioid sarcoma. A sarcoma simulating a granuloma or a carcinomaCancer2610291041PubMed Enzinger, FM 1970Epithelioid sarcoma. A sarcoma simulating a granuloma or a carcinomaCancer2610291041PubMed
4.
go back to reference Weiss, SW, Goldblum, JR 2001Malignant soft tissue tumors of uncertain typeWeiss, SWGoldblum, eds. Enzinger and Weiss’s soft tissue tumors4St LouisMosby15211538 Weiss, SW, Goldblum, JR 2001Malignant soft tissue tumors of uncertain typeWeiss, SWGoldblum,  eds. Enzinger and Weiss’s soft tissue tumors4St LouisMosby15211538
5.
go back to reference Guillou, L, Wadden, C, Coindre, JM, Krausz, T, Fletcher, CD 1997“Proximal-type” epithelioid sarcoma, a distinctive aggressive neoplasm showing rhabdoid features. Clinicopathologic, immunohistochemical, and ultrastructural study of a seriesAm J Surg Pathol21130146 Guillou, L, Wadden, C, Coindre, JM, Krausz, T, Fletcher, CD 1997“Proximal-type” epithelioid sarcoma, a distinctive aggressive neoplasm showing rhabdoid features. Clinicopathologic, immunohistochemical, and ultrastructural study of a seriesAm J Surg Pathol21130146
6.
go back to reference Hasegawa, T, Matsuno, Y, Shimoda, T, Ulmeda, T, Yokoyama, R, Hirohashi, S 2001Proximal-type epithelioid sarcoma: a clinicopathologic study of 20 casesMod Pathol14655663CrossRefPubMed Hasegawa, T, Matsuno, Y, Shimoda, T, Ulmeda, T, Yokoyama, R, Hirohashi, S 2001Proximal-type epithelioid sarcoma: a clinicopathologic study of 20 casesMod Pathol14655663CrossRefPubMed
7.
8.
go back to reference Molenaar, WM, DeJong, B, Dam-Meiring, A, Postma, A, DeVries, J, Hoekstra, HJ 1989Epithelioid sarcoma or malignant rhabdoid tumor of soft tissue? Epithelioid immunophenotype and rhabdoid karyotypeHum Pathol20347351CrossRefPubMed Molenaar, WM, DeJong, B, Dam-Meiring, A, Postma, A, DeVries, J, Hoekstra, HJ 1989Epithelioid sarcoma or malignant rhabdoid tumor of soft tissue? Epithelioid immunophenotype and rhabdoid karyotypeHum Pathol20347351CrossRefPubMed
9.
go back to reference Cordoba, JC, Parham, DM, Meyer, WH, Douglass, EC 1994A new cytogenetic finding in an epithelioid sarcoma, t(8;22)(q22;q11)Cancer Genet Cytogenet72151154CrossRefPubMed Cordoba, JC, Parham, DM, Meyer, WH, Douglass, EC 1994A new cytogenetic finding in an epithelioid sarcoma, t(8;22)(q22;q11)Cancer Genet Cytogenet72151154CrossRefPubMed
10.
go back to reference Feely, MG, Fidler, ME, Nelson, M, Neff, JR, Bridge, JA 2000Cytogenetic findings in a case of epithelioid sarcoma and a review of the literatureCancer Genet Cytogenet119155157CrossRefPubMed Feely, MG, Fidler, ME, Nelson, M, Neff, JR, Bridge, JA 2000Cytogenetic findings in a case of epithelioid sarcoma and a review of the literatureCancer Genet Cytogenet119155157CrossRefPubMed
11.
go back to reference Iwasaki, H, Ohjimi, Y, Ishiguro, M, et al. 1996Epithelioid sarcoma with an 18q aberrationCancer Genet Cytogenet914652CrossRefPubMed Iwasaki, H, Ohjimi, Y, Ishiguro, M,  et al. 1996Epithelioid sarcoma with an 18q aberrationCancer Genet Cytogenet914652CrossRefPubMed
12.
go back to reference Sonobe, H, Ohtsuki, Y, Sugimoto, T, Shimizu, K 1997Involvement of 8q, 22q, and monosomy 21 in an epithelioid sarcomaCancer Genet Cytogenet96178180CrossRefPubMed Sonobe, H, Ohtsuki, Y, Sugimoto, T, Shimizu, K 1997Involvement of 8q, 22q, and monosomy 21 in an epithelioid sarcomaCancer Genet Cytogenet96178180CrossRefPubMed
13.
go back to reference Dal Cin, P, Berghe, H, Pauwels, P 1999Epithelioid sarcoma of the proximal type with complex karyotype including i(8q)Cancer Genet Cytogenet1148082CrossRefPubMed Dal Cin, P, Berghe, H, Pauwels, P 1999Epithelioid sarcoma of the proximal type with complex karyotype including i(8q)Cancer Genet Cytogenet1148082CrossRefPubMed
14.
go back to reference Debiec-Rychter, M, Sciot, R, Hagemeijer, A 2000Common chromosome aberrations in the proximal type of epithelioid sarcomaCancer Genet Cytogenet123133136CrossRefPubMed Debiec-Rychter, M, Sciot, R, Hagemeijer, A 2000Common chromosome aberrations in the proximal type of epithelioid sarcomaCancer Genet Cytogenet123133136CrossRefPubMed
15.
16.
go back to reference Saito, T, Oda, Y, Itakura, E, et al. 2001Expression of intercellular adhesion molecules in epithelioid sarcoma and malignant rhabdoid tumorPathol Int51532542CrossRefPubMed Saito, T, Oda, Y, Itakura, E,  et al. 2001Expression of intercellular adhesion molecules in epithelioid sarcoma and malignant rhabdoid tumorPathol Int51532542CrossRefPubMed
Metadata
Title
“Proximal-type” and Classic Epithelioid Sarcomas Represent a Clinicopathologic Continuum: Case Report
Authors
Dinesh Rakheja
Kathleen S. Wilson
John Meehan
Roger A. Schultz
Ana M. Gomez
Publication date
01-02-2005
Publisher
Springer-Verlag
Published in
Pediatric and Developmental Pathology / Issue 1/2005
Print ISSN: 1093-5266
Electronic ISSN: 1615-5742
DOI
https://doi.org/10.1007/s10024-004-7086-y

Other articles of this Issue 1/2005

Pediatric and Developmental Pathology 1/2005 Go to the issue

OriginalPaper

PDP INSIGHTS