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01-06-2018 | Original Article

To assess the efficacy of socket plug technique using platelet rich fibrin with or without the use of bone substitute in alveolar ridge preservation: a prospective randomised controlled study

Published in: Oral and Maxillofacial Surgery | Issue 2/2018

Abstract

Aim

The purpose of this study is to evaluate the efficacy of Platelet Rich Fibrin (PRF) as a socket plug with or without use of Plaster of Paris (POP) as bone substitute to preserve the alveolar ridge post-extraction.

Material and methods

A prospective randomised single blind controlled study, was conducted for 18 months from November 2014 to May 2016 on 48 patients requiring extraction. All teeth were extracted atraumatically using periotomes and luxators without raising mucoperiosteal flap. Sockets were randomly allotted to groups A, B and C. Group A sockets were chosen as control, where figure of eight suture was placed. In group B sockets, PRF obtained by centrifugation was used as a socket plug and stabilised with figure of eight suture. Group C sockets were filled with POP and then covered with PRF. The socket was then closed with a figure of eight suture. Patients were informed of need for 6 months follow-up.

Results

Ninety sockets in 48 patients were subjected to our study. We found that results in the sockets where we have grafted POP showed better ridge preservation and post-operative comfort even though the difference in ridge resorption between the three groups was not statistically significant. Powered by Editorial Manager® and ProduXion Manager® from the Aries Systems Corporation.

Conclusion

Atraumatic extraction may minimise the post-operative pain and discomfort to patient as well as the post-extraction alveolar height and width changes. The use of PRF and/or bone substitute even though clinically contributes to better post-operative healing and minimal loss of alveolar width and height, the values were not statistically significant.

Irinakis T (2006) Rationale for socket preservation after extraction of a single rooted tooth when planning for future implant placement. J Can Dent Assoc 72(10):917–922PubMed

Kubilius M, Kubilis R, Gleiznys A (2012) The preservation of alveolar bone ridge during tooth extraction. Stomatologija 14:3–11PubMed

Abadzhiev M. Ridge preservation technique. Journal of IMAB–Annual Proceeding (Scientific Papers) 2009;(book)2:58–60

Pagini G, Pellegrini G, Giannobile WV, Rasperini G (2012) Postextraction alveolar ridge preservation: biological basis and treatments. Int J Dentistry:1–13

Casey DM, Lauciello FR (1980) A review of the submerged root concept. J Prosthet Dent 43(2):128–132. https://doi.org/10.1016/0022-3913(80)90174-2 CrossRefPubMed

Von Wowern N, Winther S (1980) Submergence of roots for alveolar ridge augmentation: a failure (4-year follow-up study). Int J Oral Surg 10:247–250CrossRef

Anson D (1996) Calcium sulfate: a 4-year observation of its use as a resorbable barrier in guided tissue regeneration of periodontal defects. Compend Contin Educ Dent 17:895–899PubMed

Vance GS, Greenwell H, Miller RL, Hill M, Johnston H, Scheetz JP (2004) Comparison of an allograft in an experimental putty carrier and a bovine-derived xenograft used in ridge preservation: a clinical and histologic study in humans. Int J Oral Maxillofac Implants 19:491–497PubMed

Kim S-G, Chug C-H, Kim YK, Park JC, Lim SC (2002) The use of particulate dentin-plaster of Paris combination with/without platelet rich plasma in the treatment of bone defects around implants. Int J Oral Maxillofac Implants 17(1):86–94PubMed

10.

Ricci J, Alexander H, Nadkarni P et al (2000) Biological mechanisms of calcium sulfate replacement by bone. Toronto, Em squared Inc

11.

Walsh WR, Morberg P, Yu Y, Yang JL, Haggard W, Sheath PC, Svehla M, Bruce WJM (2003) Response of a calcium sulfate bone graft substitute in a confined cancellous defect. Clin Orthop Relat Res 406:228–236. https://doi.org/10.1097/00003086-200301000-00033 CrossRef

12.

David DM, Choukroun J, Diss A, Dohan SL, Dohan A, Mouhyi J et al (2006) Platelet-rich fibrin (PRF): a second generation platelet concentrate. Part 1: technological concepts and evolution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101(3):e 45–e 50. https://doi.org/10.1016/j.tripleo.2005.07.009 CrossRef

13.

Donald D. Price. The validation of visual analogue scales as ratio scale measures for chronic and experimental pain. Pain 1983;17(Elsevier):45–56

14.

Celio-Mariano R, de Melo WM, Carneiro-Avelino C (2012) Comparative radiographic evaluation of alveolar bone healing associated with autologous platelet rich plasma after impacted mandibular third molar surgery. J Oral Maxillofac Surg 70(1):19–24. https://doi.org/10.1016/j.joms.2011.03.028 CrossRefPubMed

15.

Madras N, D’Aiuto F, Mezzomo L, Arzoumanidi M, Donos N (2011) Radiographic alveolar bone changes following ridge preservation with two different biomaterials. Clin Oral Implants Res 22(4):416–423. https://doi.org/10.1111/j.1600-0501.2010.02154.x CrossRef

16.

Van der Weijden F, Acqua FD, Slot DE (2009) Alveolar bone dimensional changes post-extraction sockets in humans: a systemic review. J Clin Periodontol 36(12):1048–1058. https://doi.org/10.1111/j.1600-051X.2009.01482.x CrossRefPubMed

17.

Mardas N, Chadha V, Donos N (2010) Alveolar ridge preservation with guided bone regeneration and a synthetic bone substitute or a bovine-derived xenograft: a randomized, controlled clinical trial. Clin Oral Implants Res 21(7):688–698. https://doi.org/10.1111/j.1600-0501.2010.01918.x CrossRefPubMed

18.

Ashman A (2000) Post-extraction ridge preservation using a synthetic alloplasts. Implant Dent 9(2):168–176CrossRefPubMed

19.

Babbush CA (2007) A new atraumatic system for tooth removal and immediate implant restoration. Implant Dent 16(2):139–145. https://doi.org/10.1097/ID.0b013e3180581656 CrossRefPubMed

20.

Adriaens PA, Van der Stede N (1998) Alveolar bone protection of extraction sites with a resorbable bilayer GBR membranes. J Dent Res 77:777–790

21.

Kotsakis G, Markou N, Chrepa V, Krompa V, Kotsakis A (2012) Alveolar ridge preservation utilizing the socket plug technique. Int J Oral Implantol Clin Res 3(1):24–30. https://doi.org/10.5005/JP-Journals-10012-1060 CrossRef

22.

Diss J, Ling H, Ye L, Xiulian H, Zhang Y, Wu H (2009) A comparative study of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) on the effect of proliferation and differentiation of rat osteoblasts in vitro. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108:707–713CrossRef

23.

Geurs N, Nitounis A, Vassilopoulos P, Velden UV, Loos BG, Reddy M (2014) Using growth factors in human extraction sockets: a histological and histomorphometric evaluation of short term healing. Int J Oral Maxillofac Implants 29(2):485–496. https://doi.org/10.11607/jomi.3408 CrossRefPubMed

24.

David MD, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, Gogly B (2006) Platelet-rich fibrin (PRF): a second generation platelet concentrate. Part 2: platelet-related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:e45–e50CrossRef

25.

Becker W, Clockie C, Sennerby L, Urist MR, Becker BE (1998) Histological findings after implantation of different grafting materials and titanium microscrews into extraction sockets: case reports. J Periodontol 69(4):414–421. https://doi.org/10.1902/jop.1998.69.4.414 CrossRefPubMed

26.

Froum S, Cho S-C, Rosenberg E, Rohrer M, Tarnow D (2002) Histological comparison of healing extraction sockets implanted with bioactive glass or demineralized freeze-dried bone allograft: a pilot study. J Periodontol 73(1):94–102CrossRefPubMed

27.

Froum S, Cho SC, Elian N, Rosenberg E, Rohrer M, Tarnow D (2004) Extraction sockets and implantation of hydroxyapatites with membrane barriers: a histologic study. Implant Dent 13(2):153–164. https://doi.org/10.1097/01.ID.0000127524.98819.FF CrossRefPubMed

28.

Guarnieri R, Pecora G, Fini M, Aldini N′N, Giardino R, Orsini G, Piattelli A (2004) Medical grade calcium sulphate hemihydrates in healing of human extraction sockets: clinical and histological observations at 3 months. J Periodontol 75(5):902–908. https://doi.org/10.1902/jop.2004.75.6.902 CrossRefPubMed

29.

Schropp L, Wenzel A, Kostopoulos L, Karring T (2003) Bone healing and soft tissue contour changes following single-tooth extraction: a clinical and radiographic 12-month prospective study. Int J Periodontics Restorative Dent 23:313–323PubMed

30.

Barone A, Ricci M, Tonelli P, Santini S, Covani U (2013) Tissue changes of extraction sockets in humans: a comparison of spontaneous healing vs. ridge preservation with secondary soft tissue healing. Clin Oral Implants Res 24(11):1231–1237PubMed

31.

Camargo PM, Lekovic V, Weinlaender M et al (2000) Influence of bioactive glass on changes in alveolar process dimensions after exodontia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 90:581–586CrossRefPubMed

32.

Nevins M, Camelo M, De Paoli S, Friedland B, Schenk RK, Parma-Benfenati S, Simion M, Tinti C, Wagenberg B (2006) A study of the fate of the buccal wall of extraction sockets of teeth with prominent roots. The International Journal of Periodontics & Restorative Dentistry 26(1):19–29

33.

Crespi R, Cappare P, Gherlone E (2009) Magnesium-enriched hydroxyapatite compared to calcium sulfate in the healing of human extraction sockets: radiographic and histomorphometric evaluation at 3 months. J Periodontol 80:210–218CrossRefPubMed

34.

Pinho MN, Roroz VL, Novaes AB Jr (2006) Titanium membranes in preservation of alveolar collapse after tooth extraction. Implant Dent 15(1):53–61. https://doi.org/10.1097/01.id.0000202596.18254.e1 CrossRefPubMed

Title: To assess the efficacy of socket plug technique using platelet rich fibrin with or without the use of bone substitute in alveolar ridge preservation: a prospective randomised controlled study
Publication date: 01-06-2018
Published in: Oral and Maxillofacial Surgery / Issue 2/2018
Print ISSN: 1865-1550
Electronic ISSN: 1865-1569
DOI: https://doi.org/10.1007/s10006-018-0680-3

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To assess the efficacy of socket plug technique using platelet rich fibrin with or without the use of bone substitute in alveolar ridge preservation: a prospective randomised controlled study

Abstract

Aim

Material and methods

Results

Conclusion

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Abstract

Aim

Material and methods

Results

Conclusion

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