Skip to main content
Top
Published in: Oral and Maxillofacial Surgery 2/2015

01-06-2015 | Original Article

Oral submucous fibrosis—a treatment protocol based on clinical study of 100 patients in central India

Authors: Pravin Lambade, Pawan Dawane, Pradip Thorat

Published in: Oral and Maxillofacial Surgery | Issue 2/2015

Login to get access

Abstract

Purpose

Oral submucous fibrosis till date is a very poorly understood and unsatisfactorily treated disease with variable signs and symptoms. In this paper, we have classified the disease in different groups according to the clinical signs, radiological assessment, histopathological confirmation, progress, and severity of disease and proposed a treatment algorithm for effective treatment of the disease in 100 patients.

Material and method

In our study, we randomly selected 100 patients of oral submucous fibrosis and classified them in to five groups based on clinical symptoms and radiological and histopathological parameters. We have given specific treatment for each group and followed them up for 2 years regularly.

Results

We found that almost all patients got symptomatic relief from the disease. Patient’s interincisal mouth opening increased significantly. All patients can take regular diet. Progressive malignant transformation can be detected earlier to avoid future morbidity and mortality.

Conclusion

Oral submucous fibrosis (OSMF) scoring index is very effective to decide the severity of disease and progress. Based on this scoring and grouping we can give definite prompt treatment to the patients with satisfactory results. Such a way this proposed scoring and staging can play major role in controlling and treating this widespread global disease.
Literature
1.
go back to reference Pindborg JJ, Sirsat SM (1966) Oral submucous fibrosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 22:764–779CrossRef Pindborg JJ, Sirsat SM (1966) Oral submucous fibrosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 22:764–779CrossRef
2.
go back to reference More C, Asrani M, Patel H, Adalja C (2010) Oral submucous fibrosis—a hospital-based retrospective study. Pearldent 1(4):25–31 More C, Asrani M, Patel H, Adalja C (2010) Oral submucous fibrosis—a hospital-based retrospective study. Pearldent 1(4):25–31
4.
go back to reference Joseph AP, Rajendran R. Submucosa precedes lamina propria in initiating fibrosis in oral submucous fibrosis—evidence based on collagen histochemistry. J Oral Maxillofac Pathol 2010 Jan–Jun;1 (1). Joseph AP, Rajendran R. Submucosa precedes lamina propria in initiating fibrosis in oral submucous fibrosis—evidence based on collagen histochemistry. J Oral Maxillofac Pathol 2010 Jan–Jun;1 (1).
5.
go back to reference Gururaj Arakeria, Peter A. Brennan, Oral submucous fibrosis: an overview of the aetiology, pathogenesis, classification, and principles of management British Journal of Oral and Maxillofacial Surgery 51 (2013) 587–593 Gururaj Arakeria, Peter A. Brennan, Oral submucous fibrosis: an overview of the aetiology, pathogenesis, classification, and principles of management British Journal of Oral and Maxillofacial Surgery 51 (2013) 587–593
6.
go back to reference More Chandramani, Das Sunanda, Patel Hetul, et al.; Proposed clinical classification for oral submucous fibrosis. Oral Oncology; in Press More Chandramani, Das Sunanda, Patel Hetul, et al.; Proposed clinical classification for oral submucous fibrosis. Oral Oncology; in Press
7.
go back to reference Rajendran R (1994) Oral submucous fibrosis: etiology, pathogenesis, and future research. Bull World Health Organ 72(6):985–996PubMedCentralPubMed Rajendran R (1994) Oral submucous fibrosis: etiology, pathogenesis, and future research. Bull World Health Organ 72(6):985–996PubMedCentralPubMed
8.
go back to reference Paymaster JC (1956) Cancer of the buccal mucosa; a clinical study of 650 cases in Indian patients. Cancer 9:431–5.10CrossRefPubMed Paymaster JC (1956) Cancer of the buccal mucosa; a clinical study of 650 cases in Indian patients. Cancer 9:431–5.10CrossRefPubMed
9.
go back to reference M.K. Gupta, Shubhangi Mhaske, Raju Ragavendra, Imtiyaz; People’s journal of scientific research; volume 1- July 08; 39–44 M.K. Gupta, Shubhangi Mhaske, Raju Ragavendra, Imtiyaz; People’s journal of scientific research; volume 1- July 08; 39–44
Metadata
Title
Oral submucous fibrosis—a treatment protocol based on clinical study of 100 patients in central India
Authors
Pravin Lambade
Pawan Dawane
Pradip Thorat
Publication date
01-06-2015
Publisher
Springer Berlin Heidelberg
Published in
Oral and Maxillofacial Surgery / Issue 2/2015
Print ISSN: 1865-1550
Electronic ISSN: 1865-1569
DOI
https://doi.org/10.1007/s10006-014-0478-x

Other articles of this Issue 2/2015

Oral and Maxillofacial Surgery 2/2015 Go to the issue