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Oral and Maxillofacial Surgery

Published in:

01-03-2011 | Case Report

Osteonecrosis of the jaw related to sunitinib

Authors: Felix P. Koch, Christian Walter, Torsten Hansen, Elke Jäger, Wilfried Wagner

Published in: Oral and Maxillofacial Surgery | Issue 1/2011

Abstract

Case Report

A 59-year-old male patient was referred to the hospital with exposed bone measuring 10 mm in diameter in the posterior, left-side region of the lower jaw. Two months previous, the first molar had been extracted. The patient had contracted renal cell carcinoma and had been treated by nephrectomy in 2003. Soft tissue metastases occurred. After initial therapy with interferon and vinblastine, a relapse occurred and the therapy was changed to sorafenib, followed by sunitinib. Osteonecrosis of the lower jaw appeared 1 year after initial and exclusive therapy with sunitinib.

Conclusions

Bisphosphonates had never been applied. With increasing application of multi-kinase inhibitors, complications due to osteonecrosis could occur more frequently.

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Title: Osteonecrosis of the jaw related to sunitinib
Authors: Felix P. Koch
Christian Walter
Torsten Hansen
Elke Jäger
Wilfried Wagner
Publication date: 01-03-2011
Publisher: Springer-Verlag
Published in: Oral and Maxillofacial Surgery / Issue 1/2011
Print ISSN: 1865-1550
Electronic ISSN: 1865-1569
DOI: https://doi.org/10.1007/s10006-010-0224-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Osteonecrosis of the jaw related to sunitinib

Abstract

Case Report

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Case Report

Conclusions

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