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Oral and Maxillofacial Surgery

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Open Access 01-03-2010 | Review Article

Application of bone growth factors—the potential of different carrier systems

Author: Henning Schliephake

Published in: Oral and Maxillofacial Surgery | Issue 1/2010

Abstract

Aim

The aim of the present review was to characterize the potential of different biomaterials as carriers for bone growth factors.

Introduction

Beyond mechanical and structural characteristics, one of the features that account for a potential carrier is the possibility to couple growth factor molecules to it. As simple adsorption of the growth factor to the carrier surface by soak loading produces a burst release of growth factors with rapid decrease of biological activity, the ability to accomplish controlled release of functional growth factor molecules is one of the crucial characteristics for an appropriate carrier material.

Conclusion

The variety of carrier materials requires different strategies to either couple growth factors to the material surface or to incorporate them into the carrier matrix. The present review outlines current technical approaches and discusses future trends in the use of carrier materials for bone growth factors.

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Title: Application of bone growth factors—the potential of different carrier systems
Author: Henning Schliephake
Publication date: 01-03-2010
Publisher: Springer-Verlag
Published in: Oral and Maxillofacial Surgery / Issue 1/2010
Print ISSN: 1865-1550
Electronic ISSN: 1865-1569
DOI: https://doi.org/10.1007/s10006-009-0185-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Application of bone growth factors—the potential of different carrier systems

Abstract

Aim

Introduction

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Aim

Introduction

Conclusion

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