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Open Access 01-09-2017 | Review

Elimination diets’ efficacy and mechanisms in attention deficit hyperactivity disorder and autism spectrum disorder

Authors: Verena Ly, Marco Bottelier, Pieter J. Hoekstra, Alejandro Arias Vasquez, Jan K. Buitelaar, Nanda N. Rommelse

Published in: European Child & Adolescent Psychiatry | Issue 9/2017

Abstract

Nutrition plays an important role in neurodevelopment. This insight has led to increasing research into the efficacy of nutrition-related interventions for treating neurodevelopmental disorders. This review discusses an elimination diet as a treatment for attention deficit hyperactivity disorder and autism spectrum disorder, with a focus on the efficacy of the food additives exclusion diet, gluten-free/casein-free diet and oligoantigenic diet. Furthermore, we discuss the potential mechanisms of elimination diets’ effects in these neurodevelopmental disorders. The main candidate mechanism is the microbiome–gut–brain axis possibly involving complex interactions between multiple systems, including the metabolic, immune, endocrine, and neural system. We conclude with practical implications and future directions into the investigation of an elimination diet’s efficacy in the treatment of attention deficit hyperactivity disorder and autism spectrum disorder.

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Title: Elimination diets’ efficacy and mechanisms in attention deficit hyperactivity disorder and autism spectrum disorder
Authors: Verena Ly
Marco Bottelier
Pieter J. Hoekstra
Alejandro Arias Vasquez
Jan K. Buitelaar
Nanda N. Rommelse
Publication date: 01-09-2017
Publisher: Springer Berlin Heidelberg
Published in: European Child & Adolescent Psychiatry / Issue 9/2017
Print ISSN: 1018-8827
Electronic ISSN: 1435-165X
DOI: https://doi.org/10.1007/s00787-017-0959-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Elimination diets’ efficacy and mechanisms in attention deficit hyperactivity disorder and autism spectrum disorder

Abstract

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

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