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European Child & Adolescent Psychiatry
Published in: European Child & Adolescent Psychiatry 2/2016

01-02-2016 | Original Contribution

Chronotherapeutic treatments for depression in youth

Authors: Stephanie Gest, Martin Holtmann, Sarah Bogen, Carina Schulz, Benjamin Pniewski, Tanja Legenbauer

Published in: European Child & Adolescent Psychiatry | Issue 2/2016

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Abstract

Chronotherapeutics such as wake therapy and bright light therapy are well-established methods in treating adults with depressive disorders and are additionally beneficent for sleep regulation. Few studies concerning chronotherapeutics in juvenile depression exist, though the established treatments are insufficient and sleep disorders often co-occur. In this study, we investigate the impact of two types of chronotherapeutics on depressive symptoms and sleep behavior in a juvenile setting. Juvenile inpatients (n = 62) with moderate to severe depressive symptoms took part in either a combined setting consisting of one night wake therapy followed by 2 weeks bright light therapy or in a setting of bright light therapy alone. Depressive symptoms, general psychopathology, clinical impression and sleep behavior were measured before (T1), directly after (T2) and 2 weeks after intervention (T3). Depressive symptoms decreased while sleep quality increased in both groups. The bright light therapy alone group showed further improvement at T3 in regards to depressive symptoms. Correlation analyses indicated significant negative correlations between sleep quality and awaking after restorative sleep with the depressive symptoms. However, only awaking after restorative sleep had a predictive impact on treatment outcome. The present study provides first evidence for a positive impact of chronotherapeutic interventions on treatment outcome in depressed juvenile inpatients. Bright light therapy seems to stabilize and further enhance reduction of depressive symptoms during follow-up, whereas one night wake therapy does not have an additional long-lasting impact on depressive symptoms and sleep parameters.
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Metadata
Title
Chronotherapeutic treatments for depression in youth
Authors
Stephanie Gest
Martin Holtmann
Sarah Bogen
Carina Schulz
Benjamin Pniewski
Tanja Legenbauer
Publication date
01-02-2016
Publisher
Springer Berlin Heidelberg
Published in
European Child & Adolescent Psychiatry / Issue 2/2016
Print ISSN: 1018-8827
Electronic ISSN: 1435-165X
DOI
https://doi.org/10.1007/s00787-015-0720-6

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