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European Child & Adolescent Psychiatry
Published in: European Child & Adolescent Psychiatry 12/2012

01-12-2012 | Review

To adhere or not, and what we can do to help

Author: F. McNicholas

Published in: European Child & Adolescent Psychiatry | Issue 12/2012

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Abstract

Two factors predict treatment outcome, how effective the treatment is and whether the patient takes or follows the treatment plan. As clinicians or scientists, we strive to develop newer and more effective treatments, both pharmacological and non-pharmacological to improve treatment outcome in our patient population. Adherence is the single most modifiable factor associated with treatment outcome, yet how often is the issue of adherence addressed in clinical consultations? The best treatment is rendered useless if not adhered to. Initial adherence rates are low and get worse with time, but methodological difficulties in studies make it difficult to determine both the clinical implication of suboptimal adherence and successful strategies. Further research should apply more rigour to the area of definition and measurement, be sufficiently powered and long term, and measure possible confounders, to allow for an understanding on the link and impact between adherence and clinical outcome. This article reviews some of the main issues with regard to adherence and cost implications of suboptimal adherence and suggests future directions.
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Metadata
Title
To adhere or not, and what we can do to help
Author
F. McNicholas
Publication date
01-12-2012
Publisher
Springer-Verlag
Published in
European Child & Adolescent Psychiatry / Issue 12/2012
Print ISSN: 1018-8827
Electronic ISSN: 1435-165X
DOI
https://doi.org/10.1007/s00787-012-0304-7

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