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01-01-2017 | Original Article

In situ effect of a CPP-ACP chewing gum on enamel erosion associated or not with abrasion

Authors: Andressa Feitosa Bezerra de Oliveira, Luciana Vilar de Oliveira Diniz, Franklin Delano Soares Forte, Fabio Correia Sampaio, Renzo Alberto Ccahuana-Vásquez, Bennett Tochukwu Amaechi

Published in: Clinical Oral Investigations | Issue 1/2017

Abstract

Objectives

The purpose of this study is to analyze the in situ effect of a casein phosphopeptide-stabilized amorphous calcium phosphate (CPP-ACP) chewing gum on human enamel erosion lesion associated or not with abrasion.

Material and methods

A three-way crossover study of 7 days was conducted involving 10 volunteers subjected to the same protocol: (G1) CPP-ACP sugar-free chewing gum, (G2) regular sugar-free chewing gum without CPP-ACP, and (G3) saliva—no chewing gum. An abrasion test was included in each phase. A 3D non-contact profilometry measurement of lesion depth and surface roughness was obtained of sound and eroded surfaces. A salivary calcium concentration was determined for all volunteers. ANOVA followed by Tukey’s test were used with a p < 0.05.

Results

The enamel depth and the enamel surface roughness of the CPP-ACP gum group were significantly lower than the others (ANOVA, p < 0.05). No significant differences were observed between the treatments when associated with abrasion (p > 0.05). A positive and significant correlation was seen between the lesion depth and enamel surface roughness for GI (r = 0.87, p = 0.00) and GIII (r = 0.79, p = 0.00) groups. The estimated total calcium presented in the saliva after the chewed CPP-ACP gum showed no statistical significance between the mean absorbance values at the different time collections (p > 0.05).

Conclusions

It is demonstrated that the incorporation of the CPP-ACP into a sugar-free gum significantly increased the remineralization/protection of eroded enamel surface.

Clinical relevance

The CPP-ACP added to gum may be a suitable alternative vehicle, to deliver calcium ions to saliva and therefore protecting enamel.

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Title: In situ effect of a CPP-ACP chewing gum on enamel erosion associated or not with abrasion
Authors: Andressa Feitosa Bezerra de Oliveira
Luciana Vilar de Oliveira Diniz
Franklin Delano Soares Forte
Fabio Correia Sampaio
Renzo Alberto Ccahuana-Vásquez
Bennett Tochukwu Amaechi
Publication date: 01-01-2017
Publisher: Springer Berlin Heidelberg
Published in: Clinical Oral Investigations / Issue 1/2017
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-016-1796-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

In situ effect of a CPP-ACP chewing gum on enamel erosion associated or not with abrasion

Abstract

Objectives

Material and methods

Results

Conclusions

Clinical relevance

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Material and methods

Results

Conclusions

Clinical relevance

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