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Clinical Oral Investigations
Published in: Clinical Oral Investigations 2/2015

01-03-2015 | Original Article

Saliva substitutes in combination with high-fluoride gel on dentin remineralization

Authors: Daniela Leal Zandim-Barcelos, Andrej M. Kielbassa, José Eduardo Cezar Sampaio, Peter Tschoppe

Published in: Clinical Oral Investigations | Issue 2/2015

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Abstract

Objective

This study aimed to determine whether the application of a high-fluoride gel could increase the remineralization of subsurface dentin lesions stored in saliva substitutes.

Materials and methods

Demineralized bovine dentin specimens were stored in mineral water (W), Glandosane (G), or modified Saliva natura (SN). Different treatments were applied twice daily: no treatment, Elmex sensitive mouth rinse (E), ProSchmelz gel (P), Duraphat toothpaste (D), ED, PD, and EPD. Differences in mineral loss were evaluated by transversal microradiography after 2 and 5 weeks.

Results

The treatments with E, D, and ED inhibited the mineral loss induced by G and enabled some mineral gain. ProSchmelz was not able to inhibit the demineralizing effect of G. This high-fluoride gel induced an erosive mineral loss in combination with G. The use of ProSchmelz in combination or not with other fluoride products did not increase remineralization of specimens stored in SN or W (p > 0.05). ProSchmelz resulted in an erosion of the specimens stored in W and revealed a lower mineralized surface layer of specimens stored in SN.

Conclusion

Topical application of high-fluoride gel reduced the mineral loss induced by G but resulted in an erosion of specimens’ surface. In addition, ProSchmelz did not demonstrate beneficial effects in combination with SN on subsurface dentin lesion remineralization.

Clinical relevance

Within the limitations of an in vitro study, it was concluded that the application of a high-fluoride gel did not promote additional effects on remineralization of subsurface dentin lesions in combination with saliva substitutes when compared to products with lower fluoride concentration.
Appendix
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Metadata
Title
Saliva substitutes in combination with high-fluoride gel on dentin remineralization
Authors
Daniela Leal Zandim-Barcelos
Andrej M. Kielbassa
José Eduardo Cezar Sampaio
Peter Tschoppe
Publication date
01-03-2015
Publisher
Springer Berlin Heidelberg
Published in
Clinical Oral Investigations / Issue 2/2015
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-014-1264-8

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