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Published in: Clinical Oral Investigations 4/2013

01-05-2013 | Review

Photodynamic therapy in dentistry: a literature review

Authors: Hare Gursoy, Ceyda Ozcakir-Tomruk, Jale Tanalp, Selçuk Yılmaz

Published in: Clinical Oral Investigations | Issue 4/2013

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Abstract

Objectives

The purpose of this review was to summarize recent developments regarding photodynamic therapy (PDT) in the field of dentistry.

Materials and methods

A review of pertinent literature was carried out in PubMED to determine the current position of PDT applications in dentistry. One hundred thirteen relevant articles were retrieved from PubMED by inserting the keywords “photodynamic therapy”, “dentistry”, “periodontology”, “oral surgery”, and “endodontics”. It is anticipated that this overview will create a specific picture in the practitioner’s mind regarding the current status and use of PDT.

Results

In spite of different results and suggestions brought about by different researchers, PDT can be considered as a promising and less invasive technique in dentistry.

Conclusion

PDT seems to be an effective tool in the treatment of localized and superficial infections. Within the limitations of the present review, it can be concluded that although PDT cannot replace antimicrobial therapy at its current stage, it may be used as an adjunctive tool for facilitating the treatment of oral infections.

Clinical relevance

Oral infections (such as mucosal and endodontic infections, periodontal diseases, caries, and peri-implantitis) are among the specific targets where PDT can be applied. Further long-term clinical studies are necessary in establishing a more specific place of the technique in the field of dentistry.
Literature
1.
go back to reference Dougherty TJ, Gomer CJ, Henderson BW et al (1998) Photodynamic therapy. J Natl Cancer Ins 90:889–905CrossRef Dougherty TJ, Gomer CJ, Henderson BW et al (1998) Photodynamic therapy. J Natl Cancer Ins 90:889–905CrossRef
2.
3.
go back to reference Sharwani A, Jerjes W, Salih V et al (2006) Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy. J Photochem Photobiol B 83:27–33PubMedCrossRef Sharwani A, Jerjes W, Salih V et al (2006) Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy. J Photochem Photobiol B 83:27–33PubMedCrossRef
4.
go back to reference Babilas P, Schreml S, Landthaler M, Szeimies RM (2010) Photodynamic therapy in dermatology: state-of-the-art. Photodermatol Photoimmunol Photomed 26:118–132PubMedCrossRef Babilas P, Schreml S, Landthaler M, Szeimies RM (2010) Photodynamic therapy in dermatology: state-of-the-art. Photodermatol Photoimmunol Photomed 26:118–132PubMedCrossRef
5.
go back to reference Sharman WM, Allen CM, van Lier JE (1999) Photodynamic therapeutics: basic principles and clinical applications. Drug Discov Today 4:507–517PubMedCrossRef Sharman WM, Allen CM, van Lier JE (1999) Photodynamic therapeutics: basic principles and clinical applications. Drug Discov Today 4:507–517PubMedCrossRef
6.
go back to reference Wainwright M (1998) Photodynamic antimicrobial chemotherapy (PACT). J Antimicrob Chemother 42:13–28PubMedCrossRef Wainwright M (1998) Photodynamic antimicrobial chemotherapy (PACT). J Antimicrob Chemother 42:13–28PubMedCrossRef
7.
go back to reference Maisch T, Szeimies RM, Jori G, Abels C (2004) Antibacterial photodynamic therapy in dermatology. Photochem Photobiol Sci 3:907–917PubMedCrossRef Maisch T, Szeimies RM, Jori G, Abels C (2004) Antibacterial photodynamic therapy in dermatology. Photochem Photobiol Sci 3:907–917PubMedCrossRef
8.
go back to reference Jori G, Fabris C, Soncin M, Ferro S, Coppellotti O, Dei D, Fantetti L, Chiti G, Roncucci G (2006) Photodynamic therapy in the treatment of microbial infections: basic principles and perspective applications. Lasers Surg Med 38:468–81PubMedCrossRef Jori G, Fabris C, Soncin M, Ferro S, Coppellotti O, Dei D, Fantetti L, Chiti G, Roncucci G (2006) Photodynamic therapy in the treatment of microbial infections: basic principles and perspective applications. Lasers Surg Med 38:468–81PubMedCrossRef
9.
go back to reference Takasaki AA, Aoki A, Mizutani K et al (2009) Application of antimicrobial photodynamic therapy in periodontal and peri-implant diseases. Periodontol 2000 2000(51):109–140CrossRef Takasaki AA, Aoki A, Mizutani K et al (2009) Application of antimicrobial photodynamic therapy in periodontal and peri-implant diseases. Periodontol 2000 2000(51):109–140CrossRef
10.
go back to reference Hematoporphyrin GJL (1991) Photodynamic therapy: is there truly a future in head and neck oncology? Reflections on a 5-year experience. Laryngoscope 101:36–42 Hematoporphyrin GJL (1991) Photodynamic therapy: is there truly a future in head and neck oncology? Reflections on a 5-year experience. Laryngoscope 101:36–42
11.
go back to reference Foote CS (1991) Definition of type I and type II photosensitized oxidation. Photochem Photobiol 54:659PubMedCrossRef Foote CS (1991) Definition of type I and type II photosensitized oxidation. Photochem Photobiol 54:659PubMedCrossRef
12.
14.
go back to reference Rossoni RD, Junqueira JC, Santos EL, Costa AC, Jorge AO (2010) Comparison of the efficacy of Rose Bengal and erythrosin in photodynamic therapy against Enterobacteriaceae. Lasers Med Sci 25:581–586PubMedCrossRef Rossoni RD, Junqueira JC, Santos EL, Costa AC, Jorge AO (2010) Comparison of the efficacy of Rose Bengal and erythrosin in photodynamic therapy against Enterobacteriaceae. Lasers Med Sci 25:581–586PubMedCrossRef
15.
go back to reference Wainwright M, Crossley KB (2004) Photosensitizing agents circumventing resistance and breaking down biofilms: a review. Int Biodeterior Biodegrad 53:119–126CrossRef Wainwright M, Crossley KB (2004) Photosensitizing agents circumventing resistance and breaking down biofilms: a review. Int Biodeterior Biodegrad 53:119–126CrossRef
16.
go back to reference Meisel P, Kocher T (2005) Photodynamic therapy for periodontal diseases: state of the art. J Photochem Photobiol B 79:159–170PubMedCrossRef Meisel P, Kocher T (2005) Photodynamic therapy for periodontal diseases: state of the art. J Photochem Photobiol B 79:159–170PubMedCrossRef
17.
go back to reference DeRosa MC, Crutchley RJ (2002) Photosensitized singlet oxygen and itsapplications. Coord Chem Rev 233–234:351–371CrossRef DeRosa MC, Crutchley RJ (2002) Photosensitized singlet oxygen and itsapplications. Coord Chem Rev 233–234:351–371CrossRef
18.
go back to reference Pinheiro SL, Schenka AA, Neto AA, de Souza CP, Rodriguez HM, Ribeiro MC (2009) Photodynamic therapy in endodontic treatment of deciduous teeth. Lasers Med Sci 24:521–526PubMedCrossRef Pinheiro SL, Schenka AA, Neto AA, de Souza CP, Rodriguez HM, Ribeiro MC (2009) Photodynamic therapy in endodontic treatment of deciduous teeth. Lasers Med Sci 24:521–526PubMedCrossRef
19.
go back to reference Sigusch BW, Pfitzner A, Albrecht V, Glockmann E (2005) Efficacy of photodynamic therapy on inflammatory signs and two selected periodontopathogenic species in a beagle dog model. J Periodontol 76:1100–1105PubMedCrossRef Sigusch BW, Pfitzner A, Albrecht V, Glockmann E (2005) Efficacy of photodynamic therapy on inflammatory signs and two selected periodontopathogenic species in a beagle dog model. J Periodontol 76:1100–1105PubMedCrossRef
20.
go back to reference Soukos NS (2000) Goodson JM (2011) Photodynamic therapy in the control of oral biofilms. Periodontol 2000 55:143–166CrossRef Soukos NS (2000) Goodson JM (2011) Photodynamic therapy in the control of oral biofilms. Periodontol 2000 55:143–166CrossRef
21.
go back to reference Allison RR, Downie GH, Cuenca R, Hu XH, Childs C, Sibata CH (2004) Photosensitizers in clinical PDT. Photodiagn Photodyn Ther 1:27–42CrossRef Allison RR, Downie GH, Cuenca R, Hu XH, Childs C, Sibata CH (2004) Photosensitizers in clinical PDT. Photodiagn Photodyn Ther 1:27–42CrossRef
22.
go back to reference Konopka K, Goslinski T (2008) Prospects for photodynamic therapy in dentistry. Biophotonics Int 15:32–35 Konopka K, Goslinski T (2008) Prospects for photodynamic therapy in dentistry. Biophotonics Int 15:32–35
23.
go back to reference Jerjes W, Upile T, Betz CS et al (2007) The application of photodynamic therapy in the head and neck. Dent Update 34:478–80, 483-4, 486PubMed Jerjes W, Upile T, Betz CS et al (2007) The application of photodynamic therapy in the head and neck. Dent Update 34:478–80, 483-4, 486PubMed
24.
go back to reference Hopper C (2000) Photodynamic therapy: a clinical reality in the treatment of cancer. Lancet Oncol 1:212–219PubMedCrossRef Hopper C (2000) Photodynamic therapy: a clinical reality in the treatment of cancer. Lancet Oncol 1:212–219PubMedCrossRef
25.
go back to reference Klot LO, Pellieux C, Briviba K, Pierlot C, Aubry JM, Sies H (1999) Mitogen-activated protein kinase (p38-, JNK-, ERK-) activation pattern induced by extracellular and intracellular singlet oxygen and UVA. Eur J Biochem 260:917–922CrossRef Klot LO, Pellieux C, Briviba K, Pierlot C, Aubry JM, Sies H (1999) Mitogen-activated protein kinase (p38-, JNK-, ERK-) activation pattern induced by extracellular and intracellular singlet oxygen and UVA. Eur J Biochem 260:917–922CrossRef
26.
27.
go back to reference Christensen E, Warloe T, Kroon S, Funk J, Helsing P, Soler AM, Stang HJ, Vatne O, Mørk C; Norwegian Photodynamic Therapy (PDT) Group (2010) Guidelines for practical use of MAL-PDT in non-melanoma skin cancer. J Eur Acad Dermatol Venereol 24(5):505–12CrossRef Christensen E, Warloe T, Kroon S, Funk J, Helsing P, Soler AM, Stang HJ, Vatne O, Mørk C; Norwegian Photodynamic Therapy (PDT) Group (2010) Guidelines for practical use of MAL-PDT in non-melanoma skin cancer. J Eur Acad Dermatol Venereol 24(5):505–12CrossRef
28.
go back to reference Braathen LR, Szeimies RM, Basset-Seguin N, Bissonnette R, Foley P, Pariser D, Roelandts R, Wennberg AM, Morton CA (2005) International Society for Photodynamic Therapy in Dermatology (2007) Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology. J Am Acad Dermatol 56(1):125–43CrossRef Braathen LR, Szeimies RM, Basset-Seguin N, Bissonnette R, Foley P, Pariser D, Roelandts R, Wennberg AM, Morton CA (2005) International Society for Photodynamic Therapy in Dermatology (2007) Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology. J Am Acad Dermatol 56(1):125–43CrossRef
29.
go back to reference Wilson M (1993) Photolysis of oral bacteria and its potential use in the treatment of caries and periodontal disease: a review. J App Bacteriol 75:299–306CrossRef Wilson M (1993) Photolysis of oral bacteria and its potential use in the treatment of caries and periodontal disease: a review. J App Bacteriol 75:299–306CrossRef
30.
go back to reference Vrouenraets MB, Visser GWM, Snow GB, van Dongen GAMS (2003) Basic principles, applications in oncology and improved selectivity of photodynamic therapy. Anticancer Res 23:505–522PubMed Vrouenraets MB, Visser GWM, Snow GB, van Dongen GAMS (2003) Basic principles, applications in oncology and improved selectivity of photodynamic therapy. Anticancer Res 23:505–522PubMed
31.
go back to reference Capella MAM, Capella LS (2003) A light in multidrug resistance: photodynamic treatment of multidrug-resistant tumors. J Biomed Sci 10:361–366PubMedCrossRef Capella MAM, Capella LS (2003) A light in multidrug resistance: photodynamic treatment of multidrug-resistant tumors. J Biomed Sci 10:361–366PubMedCrossRef
32.
go back to reference Silverman S (1999) Oral cancer: complications of therapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 88:122–126PubMedCrossRef Silverman S (1999) Oral cancer: complications of therapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 88:122–126PubMedCrossRef
33.
go back to reference Sieron A, Namyslowski G, Misiolek M, Adamek M, Kawczyk-Krupka A (2001) Photodynamic therapy of premalignant lesions and local recurrence of laryngeal and hypopharyngeal cancers. Eur Arch Otorhinolaryngol 258:349–352PubMedCrossRef Sieron A, Namyslowski G, Misiolek M, Adamek M, Kawczyk-Krupka A (2001) Photodynamic therapy of premalignant lesions and local recurrence of laryngeal and hypopharyngeal cancers. Eur Arch Otorhinolaryngol 258:349–352PubMedCrossRef
34.
go back to reference Nauta JM, von Leengoed HL, Star WM, Roodenburg JL, Witjes MJ, Verney A (1996) Photodynamic therapy of oral cancer. A review of basic mechanisms and clinical applications. Eur J Oral Sci 104:69–81PubMedCrossRef Nauta JM, von Leengoed HL, Star WM, Roodenburg JL, Witjes MJ, Verney A (1996) Photodynamic therapy of oral cancer. A review of basic mechanisms and clinical applications. Eur J Oral Sci 104:69–81PubMedCrossRef
35.
go back to reference Kubler AC, de Carpentier J, Hopper C, Leonard AG, Putnam G (2001) Treatment of squamous cell carcinoma of the lip using Foscan-mediated photodynamic therapy. Int J Oral Maxillofac Surg 30:504–509PubMedCrossRef Kubler AC, de Carpentier J, Hopper C, Leonard AG, Putnam G (2001) Treatment of squamous cell carcinoma of the lip using Foscan-mediated photodynamic therapy. Int J Oral Maxillofac Surg 30:504–509PubMedCrossRef
36.
go back to reference Copper MP, Tan IB, Oppelaar H, Ruevekamp MC, Stewart FA (2003) Meta-tetra (hydroxyphenyl)chlorin photodynamic therapy in early-stage squamous cell carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg 129:709–711PubMedCrossRef Copper MP, Tan IB, Oppelaar H, Ruevekamp MC, Stewart FA (2003) Meta-tetra (hydroxyphenyl)chlorin photodynamic therapy in early-stage squamous cell carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg 129:709–711PubMedCrossRef
37.
go back to reference Hopper C, Kubler A, Lewis H, Tan IB, Putnam G (2004) mTHPC-mediated photodynamic therapy for early oral squamous cell carcinoma. Int J Cancer 111:138–146PubMedCrossRef Hopper C, Kubler A, Lewis H, Tan IB, Putnam G (2004) mTHPC-mediated photodynamic therapy for early oral squamous cell carcinoma. Int J Cancer 111:138–146PubMedCrossRef
38.
go back to reference Rigual NR, Thankappan K, Cooper M et al (2009) Photodynamic therapy for head and neck dysplasia and cancer. Arch Otolaryngol Head Neck Surg 135:784–788PubMedCrossRef Rigual NR, Thankappan K, Cooper M et al (2009) Photodynamic therapy for head and neck dysplasia and cancer. Arch Otolaryngol Head Neck Surg 135:784–788PubMedCrossRef
39.
go back to reference Lin HP, Chen HM, Yu CH, Yang H, Wang YP, Chiang CP (2010) Topical photodynamic therapy is very effective for oral verrucous hyperplasia and oral erythroleukoplakia. J Oral Pathol Med 39:624–630PubMedCrossRef Lin HP, Chen HM, Yu CH, Yang H, Wang YP, Chiang CP (2010) Topical photodynamic therapy is very effective for oral verrucous hyperplasia and oral erythroleukoplakia. J Oral Pathol Med 39:624–630PubMedCrossRef
40.
42.
go back to reference Cerero R, Garcia-Pola MJ (2004) Management of oral lichen planus. Med Oral 9:124PubMed Cerero R, Garcia-Pola MJ (2004) Management of oral lichen planus. Med Oral 9:124PubMed
43.
go back to reference Aghahosseini F, Arbabi-Kalati F, Fashtami LA, Fateh M, Djavid GE (2006) Treatment of oral lichen planus with photodynamic therapy mediated methylene blue: a case report. Med Oral Patol Oral Cir Bucal 11:126–129 Aghahosseini F, Arbabi-Kalati F, Fashtami LA, Fateh M, Djavid GE (2006) Treatment of oral lichen planus with photodynamic therapy mediated methylene blue: a case report. Med Oral Patol Oral Cir Bucal 11:126–129
44.
go back to reference Golecka M, Oldakowska-Jedynak U, Mierzwinska-Nastalska E, Adamczyk-Sosinska E (2006) Candida-associated denture stomatitis in patients after immunosuppression therapy. Transplant Proc 38:155–156PubMedCrossRef Golecka M, Oldakowska-Jedynak U, Mierzwinska-Nastalska E, Adamczyk-Sosinska E (2006) Candida-associated denture stomatitis in patients after immunosuppression therapy. Transplant Proc 38:155–156PubMedCrossRef
45.
go back to reference Jin Y, Samaranayake LP, Samaranayake Y, Yip HK (2004) Biofilm formation of Candida albicans is variably affected by saliva and dietary sugars. Arch Oral Biol 49:789–798PubMedCrossRef Jin Y, Samaranayake LP, Samaranayake Y, Yip HK (2004) Biofilm formation of Candida albicans is variably affected by saliva and dietary sugars. Arch Oral Biol 49:789–798PubMedCrossRef
46.
go back to reference Shulman JD, Rivera-Hidalgo F, Beach MM (2005) Risk factors associated with denture stomatitis in the United States. J Oral Pathol Med 34:340–346PubMedCrossRef Shulman JD, Rivera-Hidalgo F, Beach MM (2005) Risk factors associated with denture stomatitis in the United States. J Oral Pathol Med 34:340–346PubMedCrossRef
47.
go back to reference Kulak Y, Arikan A, Delibalta N (1994) Comparison of three different treatment methods for generalized denture stomatitis. J Prosthet Dent 72:283–288PubMedCrossRef Kulak Y, Arikan A, Delibalta N (1994) Comparison of three different treatment methods for generalized denture stomatitis. J Prosthet Dent 72:283–288PubMedCrossRef
48.
go back to reference Samaranayake LP, MacFarlane TW (1981) A retrospective study of patients with recurrent chronic atrophic candidosis. Oral Surg Oral Med Oral Pathol 52:150–3PubMedCrossRef Samaranayake LP, MacFarlane TW (1981) A retrospective study of patients with recurrent chronic atrophic candidosis. Oral Surg Oral Med Oral Pathol 52:150–3PubMedCrossRef
49.
go back to reference Banting DW, Greenhorn PA, McMinn JG (1995) Effectiveness of a topical antifungal regimen for the treatment of oral candidiasis in older, chronically ill, institutionalized adults. J Can Dent Assoc 61(199–200):203–205 Banting DW, Greenhorn PA, McMinn JG (1995) Effectiveness of a topical antifungal regimen for the treatment of oral candidiasis in older, chronically ill, institutionalized adults. J Can Dent Assoc 61(199–200):203–205
50.
go back to reference Lombardi T, Budtz-Jorgensen E (1993) Treatment of denture-induced stomatitis: a review. Eur J Prosthodont Restor Dent 2:17–22PubMed Lombardi T, Budtz-Jorgensen E (1993) Treatment of denture-induced stomatitis: a review. Eur J Prosthodont Restor Dent 2:17–22PubMed
51.
go back to reference Bliss JM, Bigelow CE, Foster TH, Haidaris CG (2004) Susceptibility of Candida species to photodynamic effects of photofrin. Antimicrob Agents Chemother 48:2000–2006PubMedCrossRef Bliss JM, Bigelow CE, Foster TH, Haidaris CG (2004) Susceptibility of Candida species to photodynamic effects of photofrin. Antimicrob Agents Chemother 48:2000–2006PubMedCrossRef
52.
go back to reference Chabrier-Rosello Y, Foster TH, Pérez-Nazario N, Mitra S, Haidaris CG (2005) Sensitivity of Candida albicans germ tubes and biofilms to photofrin-mediated phototoxicity. Antimicrob Agents Chemother 49:4288–4295PubMedCrossRef Chabrier-Rosello Y, Foster TH, Pérez-Nazario N, Mitra S, Haidaris CG (2005) Sensitivity of Candida albicans germ tubes and biofilms to photofrin-mediated phototoxicity. Antimicrob Agents Chemother 49:4288–4295PubMedCrossRef
53.
go back to reference Donnelly RF, McCarron PA, Tunney MM, David Woolfson A (2007) Potential of photodynamic therapy in treatment of fungal infections of the mouth. Design and characterisation of a mucoadhesive patch containing toluidine blue OJ. Photochem Photobiol B 86:59–69CrossRef Donnelly RF, McCarron PA, Tunney MM, David Woolfson A (2007) Potential of photodynamic therapy in treatment of fungal infections of the mouth. Design and characterisation of a mucoadhesive patch containing toluidine blue OJ. Photochem Photobiol B 86:59–69CrossRef
54.
go back to reference Teichert MC, Jones JW, Usacheva MN, Biel MA (2002) Treatment of oral candidiasis with methylene blue-mediated photodynamic therapy in an immunodeficient murine model. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 93:155–160PubMedCrossRef Teichert MC, Jones JW, Usacheva MN, Biel MA (2002) Treatment of oral candidiasis with methylene blue-mediated photodynamic therapy in an immunodeficient murine model. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 93:155–160PubMedCrossRef
55.
go back to reference Donnelly RF, McCarron PA, Tunney MM (2008) Antifungal photodynamic therapy. Microbiol Res 163:1–12PubMedCrossRef Donnelly RF, McCarron PA, Tunney MM (2008) Antifungal photodynamic therapy. Microbiol Res 163:1–12PubMedCrossRef
56.
go back to reference Bertoloni G, Reddi E, Gatta M, Burlini C, Jori G (1989) Factors influencing the haematoporphyrin-sensitized photoinactivation of Candida albicans. J Gen Microbiol 135:957–966PubMed Bertoloni G, Reddi E, Gatta M, Burlini C, Jori G (1989) Factors influencing the haematoporphyrin-sensitized photoinactivation of Candida albicans. J Gen Microbiol 135:957–966PubMed
57.
go back to reference Dovigo LN, Pavarina AC, de Oliveira Mima EG, Giampaolo ET, Vergani CE, Bagnato VS (2011) Fungicidal effect of photodynamic therapy against fluconazole-resistant Candida albicans and Candida glabrata. Mycoses 54:123–30PubMedCrossRef Dovigo LN, Pavarina AC, de Oliveira Mima EG, Giampaolo ET, Vergani CE, Bagnato VS (2011) Fungicidal effect of photodynamic therapy against fluconazole-resistant Candida albicans and Candida glabrata. Mycoses 54:123–30PubMedCrossRef
58.
go back to reference Zeina B, Greenman J, Corry D, Purcell WM (2003) Antimicrobial photodynamic therapy: assessment of genotoxic effects on keratinocytes in vitro. Br J Dermatol 148:229–232PubMedCrossRef Zeina B, Greenman J, Corry D, Purcell WM (2003) Antimicrobial photodynamic therapy: assessment of genotoxic effects on keratinocytes in vitro. Br J Dermatol 148:229–232PubMedCrossRef
59.
go back to reference Zeina B, Greenman J, Corry D, Purcell WM (2002) Cytotoxic effects of antimicrobial photodynamic therapy on keratinocytes in vitro. Br J Dermatol 146:568–573PubMedCrossRef Zeina B, Greenman J, Corry D, Purcell WM (2002) Cytotoxic effects of antimicrobial photodynamic therapy on keratinocytes in vitro. Br J Dermatol 146:568–573PubMedCrossRef
60.
go back to reference Bliss JM, Bigelow CE, Foster TH, Haidaris CG (2004) Susceptibility of Candida species to photodynamic effects of photofrin. Antimicrob Agents Chemother 48:2000–2006PubMedCrossRef Bliss JM, Bigelow CE, Foster TH, Haidaris CG (2004) Susceptibility of Candida species to photodynamic effects of photofrin. Antimicrob Agents Chemother 48:2000–2006PubMedCrossRef
61.
go back to reference Marotti J, Aranha AC, Eduardo Cde P, Ribeiro MS (2009) Photodynamic therapy can be effective as a treatment for herpes simplex labialis. Photomed Laser Surg 27:357–363PubMedCrossRef Marotti J, Aranha AC, Eduardo Cde P, Ribeiro MS (2009) Photodynamic therapy can be effective as a treatment for herpes simplex labialis. Photomed Laser Surg 27:357–363PubMedCrossRef
62.
go back to reference Fimple JL, Fontana CR, Foschi F et al (2008) Photodynamic treatment of endodontic polymicrobial infection in vitro. J Endod 34:728–734PubMedCrossRef Fimple JL, Fontana CR, Foschi F et al (2008) Photodynamic treatment of endodontic polymicrobial infection in vitro. J Endod 34:728–734PubMedCrossRef
63.
go back to reference Usacheva MN, Teichert MC, Biel MA (2003) The interaction of lipopolysaccharides with phenothiazine dyes. Lasers Surg Med 33:311–319PubMedCrossRef Usacheva MN, Teichert MC, Biel MA (2003) The interaction of lipopolysaccharides with phenothiazine dyes. Lasers Surg Med 33:311–319PubMedCrossRef
64.
go back to reference Fonseca MB, Júnior PO, Pallota RC (2008) Photodynamic therapy for root canals infected with Enterococcus faecalis. Photomed Laser Surg 26:209–213PubMedCrossRef Fonseca MB, Júnior PO, Pallota RC (2008) Photodynamic therapy for root canals infected with Enterococcus faecalis. Photomed Laser Surg 26:209–213PubMedCrossRef
65.
go back to reference Neugebauer J (2005) Using photodynamic therapy to treat peri-implantitis. Interview Dent Implantol Update 16:9–16 Neugebauer J (2005) Using photodynamic therapy to treat peri-implantitis. Interview Dent Implantol Update 16:9–16
66.
go back to reference Wainwright M (1998) Photodynamic antimicrobial chemotherapy (PACT). J Antimicrob Chemother 42:13–28PubMedCrossRef Wainwright M (1998) Photodynamic antimicrobial chemotherapy (PACT). J Antimicrob Chemother 42:13–28PubMedCrossRef
67.
go back to reference Komerik N, Nakanishi H, Robert MAJ, Henderson B, Wilson M (2003) In vivo killing of Porphyromonas gingivalis by toluidine blue photosensitization in an animal model. Antimicrobial Agents Chemother 47:932–940CrossRef Komerik N, Nakanishi H, Robert MAJ, Henderson B, Wilson M (2003) In vivo killing of Porphyromonas gingivalis by toluidine blue photosensitization in an animal model. Antimicrobial Agents Chemother 47:932–940CrossRef
68.
go back to reference Paulino TP, Ribeiro KF, Thedei G Jr, Tedesco AC, Ciancaglini P (2005) Use of hand held photopolymerizer to photoinactivate Streptococcus mutans. Arch Oral Biol 50:353–359PubMedCrossRef Paulino TP, Ribeiro KF, Thedei G Jr, Tedesco AC, Ciancaglini P (2005) Use of hand held photopolymerizer to photoinactivate Streptococcus mutans. Arch Oral Biol 50:353–359PubMedCrossRef
69.
go back to reference Bevilacqua IM, Nicolau RA, Khouri S et al (2007) The impact of photodynamic therapy on the viability of Streptococcus mutans in a planktonic culture. Photomed Laser Surg 25:513–518PubMedCrossRef Bevilacqua IM, Nicolau RA, Khouri S et al (2007) The impact of photodynamic therapy on the viability of Streptococcus mutans in a planktonic culture. Photomed Laser Surg 25:513–518PubMedCrossRef
70.
go back to reference Shibli JA, Martins MC, Theodoro LH, Lotufo RFM, Garcia VG, Marcantonio E Jr (2003) Lethal photosensitization in microbiological treatment of ligature-induced peri-implantitis: a preliminary study in dogs. J Oral Sci 45:17–23PubMedCrossRef Shibli JA, Martins MC, Theodoro LH, Lotufo RFM, Garcia VG, Marcantonio E Jr (2003) Lethal photosensitization in microbiological treatment of ligature-induced peri-implantitis: a preliminary study in dogs. J Oral Sci 45:17–23PubMedCrossRef
71.
go back to reference Wilson M (1994) Bactericidal effect of laser light and its potential use in the treatment of plaque-related diseases. Int Dent J 44:181–189PubMed Wilson M (1994) Bactericidal effect of laser light and its potential use in the treatment of plaque-related diseases. Int Dent J 44:181–189PubMed
72.
go back to reference Socransky SS (2000) Haffajee AD, (2002) Dental biofilms: difficult therapeutic targets. Periodontol 2000 28:12–55CrossRef Socransky SS (2000) Haffajee AD, (2002) Dental biofilms: difficult therapeutic targets. Periodontol 2000 28:12–55CrossRef
73.
go back to reference Haffajee AD (2006) Systemic antibiotics: to use or not to use in the treatment of periodontal infections. That is the question J Clin Periodontol 33:359–361CrossRef Haffajee AD (2006) Systemic antibiotics: to use or not to use in the treatment of periodontal infections. That is the question J Clin Periodontol 33:359–361CrossRef
74.
go back to reference Preshaw PM (2004) Antibiotics in the treatment of periodontitis. Dent Update 31:448–450, 453-454, 456PubMed Preshaw PM (2004) Antibiotics in the treatment of periodontitis. Dent Update 31:448–450, 453-454, 456PubMed
75.
go back to reference Levy SB (2002) The 2000 Garrod lecture. Factors impacting on the problem of antibiotic resistance. J Antimicrob Chemother 49:25–30PubMedCrossRef Levy SB (2002) The 2000 Garrod lecture. Factors impacting on the problem of antibiotic resistance. J Antimicrob Chemother 49:25–30PubMedCrossRef
76.
go back to reference Sigusch BW, Pfitzner A, Albrecht V, Glockmann E (2005) Efficacy of photodynamic therapy on inflammatory signs and two selected periodontopathogenic species in a beagle dog model. J Periodontol 76:1100–1105PubMedCrossRef Sigusch BW, Pfitzner A, Albrecht V, Glockmann E (2005) Efficacy of photodynamic therapy on inflammatory signs and two selected periodontopathogenic species in a beagle dog model. J Periodontol 76:1100–1105PubMedCrossRef
77.
go back to reference Fontana CR, Abernethy AD, Som S et al (2009) The antibacterial effect of photodynamic therapy in dental plaque-derived biofilms. J Periodontal Res 44:751–759PubMedCrossRef Fontana CR, Abernethy AD, Som S et al (2009) The antibacterial effect of photodynamic therapy in dental plaque-derived biofilms. J Periodontal Res 44:751–759PubMedCrossRef
78.
go back to reference Wilson M, Dobson J, Sarkar S (1993) Sensitization of periodontopathogenic bacteria to killing by light from a low-power laser. Oral Microbiol Immunol 8:182–187PubMedCrossRef Wilson M, Dobson J, Sarkar S (1993) Sensitization of periodontopathogenic bacteria to killing by light from a low-power laser. Oral Microbiol Immunol 8:182–187PubMedCrossRef
79.
go back to reference Soukos NS, Ximenez-Fyvie LA, Hamblin MR, Socransky SS, Hasan T (1998) Targeted antimicrobial photochemotherapy. Antimicrob Agents Chemother 42:2595–2601PubMed Soukos NS, Ximenez-Fyvie LA, Hamblin MR, Socransky SS, Hasan T (1998) Targeted antimicrobial photochemotherapy. Antimicrob Agents Chemother 42:2595–2601PubMed
80.
go back to reference Williams JA, Pearson GJ, Colles MJ, Wilson M (2003) The effect of variable energy input from a novel light source on the photoactivated bactericidal action of toluidine blue O on Streptococcus mutans. Caries Res 37:190–193PubMedCrossRef Williams JA, Pearson GJ, Colles MJ, Wilson M (2003) The effect of variable energy input from a novel light source on the photoactivated bactericidal action of toluidine blue O on Streptococcus mutans. Caries Res 37:190–193PubMedCrossRef
81.
go back to reference Sarkar S, Wilson M (1993) Lethal photosensitization of bacteria in subgingival plaque samples from patients with chronic periodontitis. J Periodont Res 28:204–210PubMedCrossRef Sarkar S, Wilson M (1993) Lethal photosensitization of bacteria in subgingival plaque samples from patients with chronic periodontitis. J Periodont Res 28:204–210PubMedCrossRef
82.
go back to reference Metcalf D, Robinson C, Devine D, Wood S (2006) Enhancement of erythrosine-mediated photodynamic therapy of Streptococcus mutans biofilms by light fractionation. J Antimicrob Chemother 58:190–192PubMedCrossRef Metcalf D, Robinson C, Devine D, Wood S (2006) Enhancement of erythrosine-mediated photodynamic therapy of Streptococcus mutans biofilms by light fractionation. J Antimicrob Chemother 58:190–192PubMedCrossRef
83.
go back to reference Wood S, Metcalf D, Devine D, Robinson C (2006) Erythrosine is a potential photosensitizer for the photodynamic therapy of oral plaque biofilms. J Antimicrob Chemother 57:680–684PubMedCrossRef Wood S, Metcalf D, Devine D, Robinson C (2006) Erythrosine is a potential photosensitizer for the photodynamic therapy of oral plaque biofilms. J Antimicrob Chemother 57:680–684PubMedCrossRef
84.
go back to reference Zanin IC, Lobo MM, Rodrigues LK, Pimenta LA, Hofling JF, Goncalves RB (2006) Photosensitization of in vitro biofilms by toluidine blue O combined with a light-emitting diode. Eur J Oral Sci 114:64–69PubMedCrossRef Zanin IC, Lobo MM, Rodrigues LK, Pimenta LA, Hofling JF, Goncalves RB (2006) Photosensitization of in vitro biofilms by toluidine blue O combined with a light-emitting diode. Eur J Oral Sci 114:64–69PubMedCrossRef
85.
go back to reference Zanin IC, Goncalves RB, Junior AB, Hope CK, Pratten J (2005) Susceptibility of Streptococcus mutans biofilms to photodynamic therapy: an in vitro study. J Antimicrob Chemother 56:324–330PubMedCrossRef Zanin IC, Goncalves RB, Junior AB, Hope CK, Pratten J (2005) Susceptibility of Streptococcus mutans biofilms to photodynamic therapy: an in vitro study. J Antimicrob Chemother 56:324–330PubMedCrossRef
86.
go back to reference Schneider M, Kirfel G, Berthold M, Frentzen M, Krause F, Braun A (2012) The impact of antimicrobial photodynamic therapy in an artificial biofilm model. Lasers Med Sci 27:615–20PubMedCrossRef Schneider M, Kirfel G, Berthold M, Frentzen M, Krause F, Braun A (2012) The impact of antimicrobial photodynamic therapy in an artificial biofilm model. Lasers Med Sci 27:615–20PubMedCrossRef
87.
go back to reference Soukos NS, Socransky SS, Mulholland SE, Lee S, Doukas AG (2000) Photomechanical drug delivery into bacterial biofilms. Pharm Res 17:405–409PubMedCrossRef Soukos NS, Socransky SS, Mulholland SE, Lee S, Doukas AG (2000) Photomechanical drug delivery into bacterial biofilms. Pharm Res 17:405–409PubMedCrossRef
88.
go back to reference Soukos NS, Mulholland SE, Socransky SS, Doukas AG (2003) Photodestruction of human dental plaque bacteria: enhancement of the photodynamic effect by photomechanical waves in an oral biofilm model. Lasers Surg Med 33:161–168PubMedCrossRef Soukos NS, Mulholland SE, Socransky SS, Doukas AG (2003) Photodestruction of human dental plaque bacteria: enhancement of the photodynamic effect by photomechanical waves in an oral biofilm model. Lasers Surg Med 33:161–168PubMedCrossRef
89.
go back to reference Qin Y, Luan X, Bi L et al (2008) Toluidine blue-mediated photoinactivation of periodontal pathogens from supragingival plaques. Lasers Med Sci 23:49–54PubMedCrossRef Qin Y, Luan X, Bi L et al (2008) Toluidine blue-mediated photoinactivation of periodontal pathogens from supragingival plaques. Lasers Med Sci 23:49–54PubMedCrossRef
90.
go back to reference Ogura M, Abernethy AD, Blissett RD et al (2007) Photomechanical wave-assisted molecular delivery in oral biofilms. World J Microbiol Biotechnol 23:1637–1646CrossRef Ogura M, Abernethy AD, Blissett RD et al (2007) Photomechanical wave-assisted molecular delivery in oral biofilms. World J Microbiol Biotechnol 23:1637–1646CrossRef
91.
go back to reference Yilmaz S, Kuru B, Kuru L, Noyan U, Argun D, Kadir T (2002) Effect of gallium arsenide diode laser on human periodontal disease: a microbiological and clinical study. Lasers Surg Med 30:60–66PubMedCrossRef Yilmaz S, Kuru B, Kuru L, Noyan U, Argun D, Kadir T (2002) Effect of gallium arsenide diode laser on human periodontal disease: a microbiological and clinical study. Lasers Surg Med 30:60–66PubMedCrossRef
93.
go back to reference Brown SM, Allison DG, Gilbert P (1988) Resistance of bacterial biofilms to antibiotics: a growth-rate related effect? J Antimicrob Chemother 22:777–783PubMedCrossRef Brown SM, Allison DG, Gilbert P (1988) Resistance of bacterial biofilms to antibiotics: a growth-rate related effect? J Antimicrob Chemother 22:777–783PubMedCrossRef
94.
go back to reference Whiteley M, Gita Bangera M, Bumgarner RE et al (2001) Gene expression in Pseudomonas aeruginosa biofilms. Nature 413:860–864PubMedCrossRef Whiteley M, Gita Bangera M, Bumgarner RE et al (2001) Gene expression in Pseudomonas aeruginosa biofilms. Nature 413:860–864PubMedCrossRef
95.
go back to reference Andersen R, Loebel N, Hammond D, Wilson M (2007) Treatment of periodontal disease by photodisinfection compared to scaling and root planing. J Clin Dent 18:34–38PubMed Andersen R, Loebel N, Hammond D, Wilson M (2007) Treatment of periodontal disease by photodisinfection compared to scaling and root planing. J Clin Dent 18:34–38PubMed
96.
go back to reference Bhatti M, MacRobert A, Meghji S, Henderson B, Wilson M (1997) Effect of dosimetric and physiological factors on the lethal photosensitization of Porphyromonas gingivalis in vitro. Photochem Photobiol 65:1026–1031PubMedCrossRef Bhatti M, MacRobert A, Meghji S, Henderson B, Wilson M (1997) Effect of dosimetric and physiological factors on the lethal photosensitization of Porphyromonas gingivalis in vitro. Photochem Photobiol 65:1026–1031PubMedCrossRef
97.
go back to reference Anderson GG, O’Toole GA (2008) Innate and induced resistance mechanisms of bacterial biofilms. Curr Top Microbiol Immunol 322:85–105PubMedCrossRef Anderson GG, O’Toole GA (2008) Innate and induced resistance mechanisms of bacterial biofilms. Curr Top Microbiol Immunol 322:85–105PubMedCrossRef
98.
go back to reference Braun A, Dehn C, Krause F, Jepsen S (2008) Short-term clinical effects of adjunctive antimicrobial photodynamic therapy periodontal treatment: a randomized clinical trial. J Clin Periodontol 35:877–84PubMedCrossRef Braun A, Dehn C, Krause F, Jepsen S (2008) Short-term clinical effects of adjunctive antimicrobial photodynamic therapy periodontal treatment: a randomized clinical trial. J Clin Periodontol 35:877–84PubMedCrossRef
99.
go back to reference de Oliveira RR, Schwartz-Filho HO, Novaes AB Jr, Taba M Jr (2007) Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: a preliminary randomized controlled clinical study. J Periodontol 78:965–973PubMedCrossRef de Oliveira RR, Schwartz-Filho HO, Novaes AB Jr, Taba M Jr (2007) Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: a preliminary randomized controlled clinical study. J Periodontol 78:965–973PubMedCrossRef
100.
go back to reference de Oliveira RR, Schwartz-Filho HO, Novaes AB, Garlet GP, de Souza RF, Taba M, Scombatti de Souza SL, Ribeiro FJ (2009) Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: cytokine profile in gingival crevicular fluid, preliminary results. J Periodontol 80:98–105PubMedCrossRef de Oliveira RR, Schwartz-Filho HO, Novaes AB, Garlet GP, de Souza RF, Taba M, Scombatti de Souza SL, Ribeiro FJ (2009) Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: cytokine profile in gingival crevicular fluid, preliminary results. J Periodontol 80:98–105PubMedCrossRef
101.
go back to reference Campos GN, Pimentel SP, Ribeiro FV, Casarin RC, Cirano FR, Saraceni CH, Casati MZ (2012) The adjunctive effect of photodynamic therapy for residual pockets in single-rooted teeth: a randomized controlled clinical trial. Lasers Med Sci, in press Campos GN, Pimentel SP, Ribeiro FV, Casarin RC, Cirano FR, Saraceni CH, Casati MZ (2012) The adjunctive effect of photodynamic therapy for residual pockets in single-rooted teeth: a randomized controlled clinical trial. Lasers Med Sci, in press
102.
go back to reference Giannopoulou C, Cappuyns I, Cancela J, Cionca N, Mombelli A (2012) Effect of photodynamic therapy, diode laser, and deep scaling on cytokine and acute-phase protein levels in gingival crevicular fluid of residual periodontal pockets. J Periodontol 83(8):1018–27PubMedCrossRef Giannopoulou C, Cappuyns I, Cancela J, Cionca N, Mombelli A (2012) Effect of photodynamic therapy, diode laser, and deep scaling on cytokine and acute-phase protein levels in gingival crevicular fluid of residual periodontal pockets. J Periodontol 83(8):1018–27PubMedCrossRef
103.
go back to reference Mombelli A (2000) Lang NP (1998) The diagnosis and treatment of peri-implantitis. Periodontol 2000 17:63–76CrossRef Mombelli A (2000) Lang NP (1998) The diagnosis and treatment of peri-implantitis. Periodontol 2000 17:63–76CrossRef
104.
go back to reference Ericsson I, Person LG, Berglundh T, Edlund T, Lindhe J (1996) The effect of antimicrobial therapy on peri-implantitis lesions. An experimental study in the dog. Clin Oral Implant Res 7:320–328CrossRef Ericsson I, Person LG, Berglundh T, Edlund T, Lindhe J (1996) The effect of antimicrobial therapy on peri-implantitis lesions. An experimental study in the dog. Clin Oral Implant Res 7:320–328CrossRef
105.
go back to reference Machado MAN, Stefani CM, Sallum EA, Sallum AW, Tramontina VA, Nociti FH Jr (1999) Treatment of ligature-induced peri-implantitis defects by regenerative procedures: a clinical study in dogs. J Oral Sci 41:181–185PubMedCrossRef Machado MAN, Stefani CM, Sallum EA, Sallum AW, Tramontina VA, Nociti FH Jr (1999) Treatment of ligature-induced peri-implantitis defects by regenerative procedures: a clinical study in dogs. J Oral Sci 41:181–185PubMedCrossRef
106.
go back to reference Mombelli A (2002) Microbiology and antimicrobial therapy of peri-implantitis. Periodontol 2000 2000(28):177–189CrossRef Mombelli A (2002) Microbiology and antimicrobial therapy of peri-implantitis. Periodontol 2000 2000(28):177–189CrossRef
107.
go back to reference Spiekermann H (1995) Implantology. Color atlas of dental medicine. Chicago, Quintessence, pp 317–322 Spiekermann H (1995) Implantology. Color atlas of dental medicine. Chicago, Quintessence, pp 317–322
108.
go back to reference Esposito M, Hirsch J, Lekholm U, Thomsen P (1999) Differential diagnosis and treatment strategies for biologic complications and failing oral implants: a review of the literature. Int J Oral Maxillofac Implants 14:473–490PubMed Esposito M, Hirsch J, Lekholm U, Thomsen P (1999) Differential diagnosis and treatment strategies for biologic complications and failing oral implants: a review of the literature. Int J Oral Maxillofac Implants 14:473–490PubMed
109.
go back to reference Wilson M, Burns T, Pratten J, Pearson GJ (1995) Bacteria in supragingival plaque samples can be killed by low-power laser light in the presence of a photosensitizer. J Appl Bacteriol 78:569–574PubMedCrossRef Wilson M, Burns T, Pratten J, Pearson GJ (1995) Bacteria in supragingival plaque samples can be killed by low-power laser light in the presence of a photosensitizer. J Appl Bacteriol 78:569–574PubMedCrossRef
110.
go back to reference Haas R, Dörtbudak O, Mensdorff-Pouilly N, Mailath G (1997) Elimination of bacteria on different implant surfaces through photosensitization and soft laser. Clinical Oral Implant Research 8:249–254CrossRef Haas R, Dörtbudak O, Mensdorff-Pouilly N, Mailath G (1997) Elimination of bacteria on different implant surfaces through photosensitization and soft laser. Clinical Oral Implant Research 8:249–254CrossRef
111.
go back to reference Dörtbudak O, Haas R, Bernhart T, Mailath-Pokorny G (2001) Lethal photosensitization for decontamination of implant surfaces in the treatment of peri-implantitis. Clin Oral Implants Res 12:104–108PubMedCrossRef Dörtbudak O, Haas R, Bernhart T, Mailath-Pokorny G (2001) Lethal photosensitization for decontamination of implant surfaces in the treatment of peri-implantitis. Clin Oral Implants Res 12:104–108PubMedCrossRef
112.
go back to reference Hayek RR, Araújo NS, Gioso MA et al (2005) Comparative study between the effects of photodynamic therapy and conventional therapy on microbial reduction in ligature-induced peri-implantitis in dogs. J Periodontol 76:1275–1281PubMedCrossRef Hayek RR, Araújo NS, Gioso MA et al (2005) Comparative study between the effects of photodynamic therapy and conventional therapy on microbial reduction in ligature-induced peri-implantitis in dogs. J Periodontol 76:1275–1281PubMedCrossRef
113.
go back to reference Kömerik N, MacRobert AJ (2006) Photodynamic therapy as an alternative antimicrobial modality for oral infections. J Environ Pathol Toxicol Oncol 25:487–504PubMedCrossRef Kömerik N, MacRobert AJ (2006) Photodynamic therapy as an alternative antimicrobial modality for oral infections. J Environ Pathol Toxicol Oncol 25:487–504PubMedCrossRef
114.
go back to reference Wilson BC (2002) Photodynamic therapy for cancer: principles. Can J Gastroenterol 16:393–396PubMed Wilson BC (2002) Photodynamic therapy for cancer: principles. Can J Gastroenterol 16:393–396PubMed
116.
go back to reference Fimple JL, Fontana CR, Foschi F, Ruggiero K, Song X, Pagonis TC, Tanner AC, Kent R, Doukas AG, Stashenko PP, Soukos NS (2008) Photodynamic treatment of endodontic polymicrobial infection in vitro. J Endod 34:728–734PubMedCrossRef Fimple JL, Fontana CR, Foschi F, Ruggiero K, Song X, Pagonis TC, Tanner AC, Kent R, Doukas AG, Stashenko PP, Soukos NS (2008) Photodynamic treatment of endodontic polymicrobial infection in vitro. J Endod 34:728–734PubMedCrossRef
117.
go back to reference Xu Y, Young MJ, Battaglino RA, Morse LR, Fontana CR, Pagonis TC, Kent R, Soukos NS (2009) Endodontic antimicrobial photodynamic therapy: safety assessment in mammalian cell cultures. J Endod 35:1567–1572PubMedCrossRef Xu Y, Young MJ, Battaglino RA, Morse LR, Fontana CR, Pagonis TC, Kent R, Soukos NS (2009) Endodontic antimicrobial photodynamic therapy: safety assessment in mammalian cell cultures. J Endod 35:1567–1572PubMedCrossRef
118.
go back to reference Silva LA, Novaes AB Jr, de Oliveira RR, Nelson-Filho P, Santamaria M Jr, Silva RA (2012) Antimicrobial photodynamic therapy for the treatment of teeth with apical periodontitis: a histopathological evaluation. J Endod 38(3):360–6PubMedCrossRef Silva LA, Novaes AB Jr, de Oliveira RR, Nelson-Filho P, Santamaria M Jr, Silva RA (2012) Antimicrobial photodynamic therapy for the treatment of teeth with apical periodontitis: a histopathological evaluation. J Endod 38(3):360–6PubMedCrossRef
119.
go back to reference Nagayoshi M, Nishihara T, Nakashima K, Iwaki S, Chen KK, Terashita M, Kitamura C (2011) Bactericidal effects of diode laser irradiation on Enterococcus faecalis using periapical lesion defect model. ISRN Dent.:870364. Nagayoshi M, Nishihara T, Nakashima K, Iwaki S, Chen KK, Terashita M, Kitamura C (2011) Bactericidal effects of diode laser irradiation on Enterococcus faecalis using periapical lesion defect model. ISRN Dent.:870364.
120.
go back to reference Pagonis TC, Chen J, Fontana CR, Devalapally H, Ruggiero K, Song X, Foschi F, Dunham J, Skobe Z, Yamazaki H, Kent R, Tanner AC, Amiji MM, Soukos NS (2010) Nanoparticle-based endodontic antimicrobial photodynamic therapy. J Endod 36:322–328PubMedCrossRef Pagonis TC, Chen J, Fontana CR, Devalapally H, Ruggiero K, Song X, Foschi F, Dunham J, Skobe Z, Yamazaki H, Kent R, Tanner AC, Amiji MM, Soukos NS (2010) Nanoparticle-based endodontic antimicrobial photodynamic therapy. J Endod 36:322–328PubMedCrossRef
122.
go back to reference Garcez AS, Nuñez SC, Hamblim MR, Suzuki H, Ribeiro MS (2010) Photodynamic therapy associated with conventional endodontic treatment in patients with antibiotic-resistant microflora: a preliminary report. J Endod 36:1463–1466PubMedCrossRef Garcez AS, Nuñez SC, Hamblim MR, Suzuki H, Ribeiro MS (2010) Photodynamic therapy associated with conventional endodontic treatment in patients with antibiotic-resistant microflora: a preliminary report. J Endod 36:1463–1466PubMedCrossRef
124.
go back to reference Ng R, Singh F, Papamanou DA, Song X, Patel C, Holewa C, Patel N, Klepac-Ceraj V, Fontana CR, Kent R, Pagonis TC, Stashenko PP (2011) Soukos NS (2011) Endodontic photodynamic therapy ex vivo. J Endod 37:217–222PubMedCrossRef Ng R, Singh F, Papamanou DA, Song X, Patel C, Holewa C, Patel N, Klepac-Ceraj V, Fontana CR, Kent R, Pagonis TC, Stashenko PP (2011) Soukos NS (2011) Endodontic photodynamic therapy ex vivo. J Endod 37:217–222PubMedCrossRef
125.
go back to reference Nunes MR, Mello I, Franco GC, de Medeiros JM, Dos Santos SS, Habitante SM, Lage-Marques JL, Raldi DP (2011) Effectiveness of photodynamic therapy against Enterococcus faecalis, with and without the use of an intracanal optical fiber: an in vitro study. Photomed Laser Surg 29:803–8. doi:10.1089/pho.2011.2995 PubMedCrossRef Nunes MR, Mello I, Franco GC, de Medeiros JM, Dos Santos SS, Habitante SM, Lage-Marques JL, Raldi DP (2011) Effectiveness of photodynamic therapy against Enterococcus faecalis, with and without the use of an intracanal optical fiber: an in vitro study. Photomed Laser Surg 29:803–8. doi:10.​1089/​pho.​2011.​2995 PubMedCrossRef
126.
go back to reference Carvalho Edos S, Mello I, Albergaria SJ, Habitante SM, Lage-Marques JL, Raldi DP (2011) Effect of chemical substances in removing methylene blue after photodynamic therapy in root canal treatment. Photomed Laser Surg 29:559–63, Epub 2011 Jun 1PubMedCrossRef Carvalho Edos S, Mello I, Albergaria SJ, Habitante SM, Lage-Marques JL, Raldi DP (2011) Effect of chemical substances in removing methylene blue after photodynamic therapy in root canal treatment. Photomed Laser Surg 29:559–63, Epub 2011 Jun 1PubMedCrossRef
Metadata
Title
Photodynamic therapy in dentistry: a literature review
Authors
Hare Gursoy
Ceyda Ozcakir-Tomruk
Jale Tanalp
Selçuk Yılmaz
Publication date
01-05-2013
Publisher
Springer-Verlag
Published in
Clinical Oral Investigations / Issue 4/2013
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-012-0845-7

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