Skip to main content
Top
Published in: Journal of Orthopaedic Science 5/2015

01-09-2015 | Original Article

Development of a support tool for the clinical diagnosis of symptomatic lumbar intra- and/or extra-foraminal stenosis

Authors: Hiroshi Yamada, Hiroyuki Oka, Hiroshi Iwasaki, Toru Endo, Masahiko Kioka, Yuyu Ishimoto, Keiji Nagata, Noboru Takiguchi, Hiroshi Hashizume, Akihito Minamide, Yukihiro Nakagawa, Masaki Kawai, Shunji Tsutsui, Munehito Yoshida

Published in: Journal of Orthopaedic Science | Issue 5/2015

Login to get access

Abstract

Background

Not all lumbar intra- and/or extra-foraminal stenosis (LIEFS) on MRI is symptomatic. Therefore, the establishment of clinical diagnostic tools that can identify patients with symptomatic LIEFS is crucial in the clinical setting. The aim of this study was to develop a support tool for clinical diagnosis of LIEFS.

Methods

Patients with L5 radiculopathy alone were prospectively enrolled. Fifty-one patients with lumbar spinal canal stenosis only at the L4–5 level and 49 patients with LIEFS only at the L5–S1 level were extracted from this cohort. We compared the two groups with regard to 12 variables—three subjective and three objective items from the Japanese Orthopaedic Association (JOA) score; Kemp’s sign; results of the lumbar flexion test, Bonnet test, and Freiberg test; pain on sitting; and pain when recumbent—to determine which factors were associated with a high index of clinical suspicion of LIEFS.

Results

The significant predictors of a final diagnosis of LIEFS were identified as follows: pain when recumbent, Freiberg and Bonnet test results, and pain on sitting. To develop a diagnostic tool, a scoring system (0–20 points) was formulated on the basis of the contribution ratios of these risk factors. To determine the contribution ratio, an integer score was assigned to the identified risk factors as follows: pain when recumbent = 9 points, Freiberg = 5 points, Bonnet = 3 points, and pain on sitting = 3 points. The Hosmer–Lemeshow statistic for this scoring system was p = 0.063, and confirmed that it was a good model. Receiver operating characteristic (ROC) curve analysis demonstrated a cut-off value of 5 points, an area under the ROC curve of 0.87435, sensitivity of 75.5 %, and specificity of 82.3 %.

Conclusions

We believe that the use of this tool in the clinical setting will improve the accuracy of diagnosing symptomatic LIEFS, which will lead to improved quality of patient care.
Literature
1.
go back to reference Arnoldi CC, Brodsky AE, Cauchoix J, Dommisse CGF, Edgar MA, Gargano FP, Jacobson RE, Kirkaldy-Willis WH, Kurihara A, Langenskiold A, Macnab I, McIvor WD, Paine KWE, Russin LA, Sheldon J, Tile M, Urist, Wilson WE, Wiltse LL. Lumbar spinal stenosis and nerve root entrapment syndromes: definition and classification. Clin Orthop Relat Res. 1976;115:4–5.PubMed Arnoldi CC, Brodsky AE, Cauchoix J, Dommisse CGF, Edgar MA, Gargano FP, Jacobson RE, Kirkaldy-Willis WH, Kurihara A, Langenskiold A, Macnab I, McIvor WD, Paine KWE, Russin LA, Sheldon J, Tile M, Urist, Wilson WE, Wiltse LL. Lumbar spinal stenosis and nerve root entrapment syndromes: definition and classification. Clin Orthop Relat Res. 1976;115:4–5.PubMed
2.
go back to reference Briggs H, Krause J. The intervertebral foraminotomy for relief of sciatic pain. J Bone Joint Surg. 1945;27:475–8. Briggs H, Krause J. The intervertebral foraminotomy for relief of sciatic pain. J Bone Joint Surg. 1945;27:475–8.
3.
go back to reference MacNab I. Negative disc exploration. An analysis of the causes of nerve root involvement in sixty-eight patients. J Bone Joint Surg Am. 1971;53(5):891–903.PubMed MacNab I. Negative disc exploration. An analysis of the causes of nerve root involvement in sixty-eight patients. J Bone Joint Surg Am. 1971;53(5):891–903.PubMed
4.
go back to reference Lee CK, Rauschning W, Glenn W. Lateral lumbar spinal canal stenosis: classification, pathologic anatomy, and surgical decompression. Spine. 1988;13(3):313–20.CrossRefPubMed Lee CK, Rauschning W, Glenn W. Lateral lumbar spinal canal stenosis: classification, pathologic anatomy, and surgical decompression. Spine. 1988;13(3):313–20.CrossRefPubMed
5.
go back to reference Hasue M, Kunogi J, Konno S, Kikuchi S. Classification by position of dorsal root ganglia in the lumbosacral region. Spine. 1989;14(11):1261–4.CrossRefPubMed Hasue M, Kunogi J, Konno S, Kikuchi S. Classification by position of dorsal root ganglia in the lumbosacral region. Spine. 1989;14(11):1261–4.CrossRefPubMed
6.
go back to reference Porter R, Hibbert C, Evans C. The natural history of root entrapment syndrome. Spine. 1984;9(4):418–21.CrossRefPubMed Porter R, Hibbert C, Evans C. The natural history of root entrapment syndrome. Spine. 1984;9(4):418–21.CrossRefPubMed
7.
go back to reference Vanderlinden R. Subarticular entrapment of the dorsal root ganglion as a cause of sciatic pain. Spine. 1984;9(1):19–22.CrossRefPubMed Vanderlinden R. Subarticular entrapment of the dorsal root ganglion as a cause of sciatic pain. Spine. 1984;9(1):19–22.CrossRefPubMed
8.
go back to reference Kunogi J, Hasue M. Diagnosis and operative treatment of intraforaminal and extraforaminal nerve root compression. Spine. 1991;16(11):1312–30.CrossRefPubMed Kunogi J, Hasue M. Diagnosis and operative treatment of intraforaminal and extraforaminal nerve root compression. Spine. 1991;16(11):1312–30.CrossRefPubMed
9.
go back to reference Burton CV, Kirkaldy-Willis W, Yong-Hing K, Heithoff KB. Causes of failure of surgery on the lumbar spine. Clin Orthop Relat Res. 1981;157:191–9.PubMed Burton CV, Kirkaldy-Willis W, Yong-Hing K, Heithoff KB. Causes of failure of surgery on the lumbar spine. Clin Orthop Relat Res. 1981;157:191–9.PubMed
10.
go back to reference Schofferman J, Reynolds J, Herzog R, Covington E, Dreyfuss P, O’Beill C. Failed back surgery: etiology and diagnostic evaluation. Spine J. 2003;3:400–3.CrossRefPubMed Schofferman J, Reynolds J, Herzog R, Covington E, Dreyfuss P, O’Beill C. Failed back surgery: etiology and diagnostic evaluation. Spine J. 2003;3:400–3.CrossRefPubMed
11.
go back to reference Maher CO, Henderson FC. Lateral exit-zone stenosis and lumbar radiculopathy. J Neurosurg. 1999;90(1 Suppl):52–8.PubMed Maher CO, Henderson FC. Lateral exit-zone stenosis and lumbar radiculopathy. J Neurosurg. 1999;90(1 Suppl):52–8.PubMed
12.
go back to reference Hashimoto M, Watanabe O, Hirano H. Extraforaminal stenosis in the lumbosacral spine. Efficacy of MR imaging in the coronal plane. Acta Radiol. 1996;37:610–3.PubMed Hashimoto M, Watanabe O, Hirano H. Extraforaminal stenosis in the lumbosacral spine. Efficacy of MR imaging in the coronal plane. Acta Radiol. 1996;37:610–3.PubMed
13.
go back to reference Boden SD, Davis DO, Dina TS, Patronas NJ, Wiesel SW. Abnormal magnetic-resonance scans of the lumbar spine in asymptomatic subjects. A prospective investigation. J Bone Joint Surg Am. 1990;72(3):403–8.PubMed Boden SD, Davis DO, Dina TS, Patronas NJ, Wiesel SW. Abnormal magnetic-resonance scans of the lumbar spine in asymptomatic subjects. A prospective investigation. J Bone Joint Surg Am. 1990;72(3):403–8.PubMed
14.
go back to reference Yamada H, Yoshida M, Hashizume H, Minamide A, Nakagawa Y, Kawai M, Iwasaki H, Tsutsui S. Efficacy of novel minimally invasive surgery using spinal microendoscope for treating extraforaminal stenosis at the lumbosacral junction. J Spinal Disord Tech. 2012;25(5):268–76.CrossRefPubMed Yamada H, Yoshida M, Hashizume H, Minamide A, Nakagawa Y, Kawai M, Iwasaki H, Tsutsui S. Efficacy of novel minimally invasive surgery using spinal microendoscope for treating extraforaminal stenosis at the lumbosacral junction. J Spinal Disord Tech. 2012;25(5):268–76.CrossRefPubMed
15.
go back to reference Yamada H, Terada M, Iwasaki H, Endo T, Okada M, Nakao S, Hashizume H, Minamide A, Nakagawa Y, Nishi H, Tsutsui S, Oka H, Yoshida M. Improved diagnostic accuracy of lumbar intra-and/or extra-foraminal stenosis by use of three dimensional MR imaging: comparison with conventional MR imaging. J Orthop Sci. 2015;20(2):287–94.CrossRefPubMed Yamada H, Terada M, Iwasaki H, Endo T, Okada M, Nakao S, Hashizume H, Minamide A, Nakagawa Y, Nishi H, Tsutsui S, Oka H, Yoshida M. Improved diagnostic accuracy of lumbar intra-and/or extra-foraminal stenosis by use of three dimensional MR imaging: comparison with conventional MR imaging. J Orthop Sci. 2015;20(2):287–94.CrossRefPubMed
17.
go back to reference Freiberg AH, Vinkle TH. Sciatica and the sacro-iliac joint. J Bone Joint Surg Am. 1934;16:126–36. Freiberg AH, Vinkle TH. Sciatica and the sacro-iliac joint. J Bone Joint Surg Am. 1934;16:126–36.
18.
go back to reference Nakamura H, Seki M, Konishi S, Yamano Y, Takaoka K. Pirifomis syndrome diagnosed by cauda equina action potentials: report of two cases. Spine. 2003;28(2):E37–40.CrossRefPubMed Nakamura H, Seki M, Konishi S, Yamano Y, Takaoka K. Pirifomis syndrome diagnosed by cauda equina action potentials: report of two cases. Spine. 2003;28(2):E37–40.CrossRefPubMed
19.
go back to reference Baba H, Uchida K, Maezawa Y, Furusawa N, Okumura Y, Imura S. Microsurgical nerve root canal widening without fusion for lumbosacral intervertebral foraminal stenosis: technical notes and early results. Spinal Cord. 1996;34:644–50.CrossRefPubMed Baba H, Uchida K, Maezawa Y, Furusawa N, Okumura Y, Imura S. Microsurgical nerve root canal widening without fusion for lumbosacral intervertebral foraminal stenosis: technical notes and early results. Spinal Cord. 1996;34:644–50.CrossRefPubMed
21.
go back to reference Watanabe K, Yamazaki A, Morita O, Sano A, Katsumi K, Ohashi M. Clinical outcomes of posterior lumbar interbody fusion for lumbar foraminal stenosis: preoperative diagnosis and surgical strategy. J Spinal Disord Tech. 2011;24(3):137–41.CrossRefPubMed Watanabe K, Yamazaki A, Morita O, Sano A, Katsumi K, Ohashi M. Clinical outcomes of posterior lumbar interbody fusion for lumbar foraminal stenosis: preoperative diagnosis and surgical strategy. J Spinal Disord Tech. 2011;24(3):137–41.CrossRefPubMed
22.
go back to reference Watters WC, Baisden J, Gilbert TJ, Kreiner S, Resnick DK, Bono CM, Ghiselli G, Heggeness MH, Mazanec DJ, O’Neill C, Reitman CA, Shaffer WO, Summers JT, Toton JF. Degenerative lumbar spinal stenosis: an evidence-based clinical guideline for the diagnosis and treatment of degenerative lumbar spinal stenosis. Spine J. 2008;8:305–10.CrossRefPubMed Watters WC, Baisden J, Gilbert TJ, Kreiner S, Resnick DK, Bono CM, Ghiselli G, Heggeness MH, Mazanec DJ, O’Neill C, Reitman CA, Shaffer WO, Summers JT, Toton JF. Degenerative lumbar spinal stenosis: an evidence-based clinical guideline for the diagnosis and treatment of degenerative lumbar spinal stenosis. Spine J. 2008;8:305–10.CrossRefPubMed
23.
go back to reference Filler AG, Haynes J, Jordan SE, Prager J, Villablanca JP, Farahani K, McBride DQ, Tsuruda JS, Morisoli B, Batzdorf U, Johnson JP. Sciatica of nondisc origin and piriformis syndrome: diagnosis by magnetic resonance neurography and interventional magnetic resonance imaging with outcome study of resulting treatment. J Neurosurg Spine. 2005;2:99–115.CrossRefPubMed Filler AG, Haynes J, Jordan SE, Prager J, Villablanca JP, Farahani K, McBride DQ, Tsuruda JS, Morisoli B, Batzdorf U, Johnson JP. Sciatica of nondisc origin and piriformis syndrome: diagnosis by magnetic resonance neurography and interventional magnetic resonance imaging with outcome study of resulting treatment. J Neurosurg Spine. 2005;2:99–115.CrossRefPubMed
Metadata
Title
Development of a support tool for the clinical diagnosis of symptomatic lumbar intra- and/or extra-foraminal stenosis
Authors
Hiroshi Yamada
Hiroyuki Oka
Hiroshi Iwasaki
Toru Endo
Masahiko Kioka
Yuyu Ishimoto
Keiji Nagata
Noboru Takiguchi
Hiroshi Hashizume
Akihito Minamide
Yukihiro Nakagawa
Masaki Kawai
Shunji Tsutsui
Munehito Yoshida
Publication date
01-09-2015
Publisher
Springer Japan
Published in
Journal of Orthopaedic Science / Issue 5/2015
Print ISSN: 0949-2658
Electronic ISSN: 1436-2023
DOI
https://doi.org/10.1007/s00776-015-0743-3

Other articles of this Issue 5/2015

Journal of Orthopaedic Science 5/2015 Go to the issue