Top

Published in:

01-11-2015 | Case Report

Cervical myelopathy due to calcification of the posterior atlantoaxial membrane associated with generalized articular deposition of calcium pyrophosphate dihydrate: a case report and review of the literature

Authors: Kanji Mori, Shinji Imai, Kazuya Nishizawa, Yoshitaka Matsusue

Published in: Journal of Orthopaedic Science | Issue 6/2015

Excerpt

The ligamentum flavum can undergo either calcification or ossification that can lead to radiculomyelopathy [1, 2]. Calcification of the ligamentum flavum (CLF) characteristically occurs in the cervical spine in elderly women [1]. Theoretically speaking, calcification of the spinal ligament can affect any level of the cervical spine; however, we seldom encounter calcification of the posterior atlantoaxial membrane. …

Miyasaka K, Kaneda K, Sato S, Iwasaki Y, Abe S, Takei H, Tsuru M, Tashiro K, Abe H, Fujioka Y. Myelopathy due to ossification or calcification of the ligamentum flavum: radiologic and histologic evaluations. AJNR Am J Neuroradiol. 1983;4(3):629–32.PubMed

Imai S, Hukuda S. Cervical radiculomyelopathy due to deposition of calcium pyrophosphate dihydrate crystals in the ligamentum flavum: historical and histological evaluation of attendant inflammation. J Spinal Disord. 1994;7(6):513–7.CrossRefPubMed

Ellman MH, Vazquez T, Ferguson L, Mandel N. Calcium pyrophosphate deposition in ligamentum flavum. Arthritis Rheum. 1978;21(5):611–3.CrossRefPubMed

Kamakura K, Nanko S, Furukawa T, Mannen T, Toyokura Y. Cervical radiculomyelopathy due to calcified ligamenta flava. Ann Neurol. 1979;5(2):193–5.CrossRefPubMed

Baba H, Maezawa Y, Kawahara N, Tomita K, Furusawa N, Imura S. Calcium crystal deposition in the ligamentum flavum of the cervical spine. Spine (Phila Pa 1976). 1993;18(15):2174–81.CrossRef

Inoue H, Seichi A, Kimura A, Endo T, Hoshino Y. Multiple-level ossification of the ligamentum flavum in the cervical spine combined with calcification of the cervical ligamentum flavum and posterior atlanto-axial membrane. Eur Spine J. 2013;22(Suppl 3):S416–20.CrossRefPubMed

Nakajima K, Miyaoka M, Sumie H, Nakazato T, Ishii S. Cervical radiculomyelopathy due to calcification of the ligamenta flava. Surg Neurol. 1984;21(5):479–88.CrossRefPubMed

Okada G, Hosoi S, Kato K, Ohta K, Tachi Y, Sonoda J, Yada H. Case report 779. Carbonate apatite calcification of ligamentum flavum. Skeletal Radiol. 1993;22(3):211–3.CrossRefPubMed

Mwaka ES, Yayama T, Uchida K, Kobayashi S, Kokubo Y, Nakajima H, Sato R, Orwotho NT, Baba H. Calcium pyrophosphate dihydrate crystal deposition in the ligamentum flavum of the cervical spine: histopathological and immunohistochemical findings. Clin Exp Rheumatol. 2009;27(3):430–8.PubMed

10.

Ramsey RH. The anatomy of the ligamenta flava. Clin Orthop Relat Res. 1966;44:129–40.PubMed

11.

Iwasaki Y, Akino M, Abe H, Tsuru M, Tashiro K, Miyasaka K, Kaneda K, Isu T, Ito T. Calcification of the ligamentum flavum of the cervical spine. Report of four cases. J Neurosurg. 1983;59(3):531–4.CrossRefPubMed

12.

Ogata M, Ishikawa K, Ohira T. Cervical myelopathy in pseudogout. Case report. J Bone Joint Surg Am. 1984;66(8):1301–3.PubMed

13.

Cabre P, Pascal-Moussellard H, Kaidomar S, Bucki B, Bardin T, Smadja D, Arfi S. Six cases of cervical ligamentum flavum calcification in Blacks in the French West Indies. Joint Bone Spine. 2001;68(2):158–65.CrossRefPubMed

14.

Nanko S, Takagi A, Mannen T, et al. A case of radiculo-myelopathy due to calcification of the ligamentum flavum. Shinkeinaika. 1976;4(3):205–10 (in Japanese).

15.

Akino M, Abe H, Iwasaki Y, Hokin K, Tsuru M, Koiwa M, Saito H. Case of cervical myelopathy due to calcified mass in the cervical yellow ligament. No Shinkei Geka. 1983;11(2):173–8.

16.

Jyotoku Z, Harada H. A case of cervical myelopathy due to calcification of the ligamentum flavum. Rinsho Seikei Geka. 1980;15(7):708–12 (in Japanese).

17.

Kawano N, Yoshida S, Ohwada T, Yada K, Sasaki K, Matsuno T. Cervical radiculomyelopathy caused by deposition of calcium pyrophosphate dihydrate crystals in the ligamenta flava. Case report. J Neurosurg. 1980;52(2):279–83.

18.

Kida H, Tabata S. Calcified mass in the cervical ligament flava as a cause of cervical myelopathy. Rinsho Seikei Geka. 1981;16(3):310–3 (in Japanese).

19.

Nagashima C, Takahama M, Shibata K, et al. CPPD crystal deposition in the cervical ligament flava producing cervical myelopathy with special reference to the scanning electron microscopic and X-ray microanalytic studies. J Saitama Med School. 1981;8(1,2):33–45 (in Japanese).

20.

Fujiwara M, Bitoh S, Hasegawa H, Nakata M, Hata H. A case of nodular calcification of the ligamentum flavum with ossification of the posterior longitudinal ligament in the cervical spine. No Shinkei Geka. 1982;10(7):769–74 (in Japanese).

21.

Hirano H, Nakanishi K, Mimatsu K, et al. Myelopathy due to calcium deposition in the cervical ligament flava. Report of two cases. Cent Jpn J Orthop Traumat. 1985;28(1):447–9 (in Japanese).

22.

Berghausen EJ, Balogh K, Landis WJ, Lee DD, Wright AM. Cervical myelopathy attributable to pseudogout. Case report with radiologic, histologic, and crystallographic observations. Clin Orthop Relat Res. 1987;214:217–21.

23.

Kubota T, Kawano H, Yamashima T, Ikeda K, Hayashi M, Yamamoto S. Ultrastructural study of calcification process in the ligamentum flavum of the cervical spine. Spine. 1987;12(4):317–23.

24.

Kawano N, Matsuno T, Miyazawa S, Iida H, Yada K, Kobayashi N, Iwasaki Y. Calcium pyrophosphate dihydrate crystal deposition disease in the cervical ligamentum flavum. J Neurosurg. 1988;68(4):613–20.

25.

Hankey GJ, Khangure MS. Cervical myelopathy due to calcification of the ligamentum flavum. Aust N Z J Surg. 1988;58(3):247–9.

26.

Gomez H, Chou SM. Myeloradiculopathy secondary to pseudogout in the cervical ligamentum flavum: case report. Neurosurgery. 1989;25(2):298–302

27.

Sato K, Hayashi M, Kubota T, Kawano H, Handa Y, Kabuto M. Symptomatic calcification and ossification of the cervical ligamentum flavum: clinical, radiological and pathological features. Br J Neurosurg. 1989;3(5):597–602.

28.

Ohnishi H, Kurihara A, Uratsuji M, et al. Three cases of cervical myelopathy due to calcification of yellow ligament. Seikeigeka. 1992;43(5):655–60 (in Japanese).

29.

Takayama S, Kuribayashi K, Miyamoto Y, Nakasu Y, Handa J. Ossification and calcification of the cervical ligamentum flavum—case reports. No To Shinkei. 1993;45(9):859–63 (in Japanese).

30.

Haraguchi K, Yamaki T, Kurokawa Y, Ohtaki M, Ibayashi Y, Uede T, Tanabe S, Hashi K. A case of calcification of the cervical ligamentum flavum. No Shinkei Geka. 1996;24(1):69–73 (in Japanese).

31.

Higashi S, Hamada J, Ono W, Tamai K, Saotome K. Calcification of cervical ligamentum flavum—analysis of calcium compounds and histopathological findings. Ryumachi. 1997;37(6):794–803 (in Japanese).

32.

Yamagami T, Kawano N, Nakano H. Calcification of the cervical ligamentum flavum—case report. Neurol Med Chir (Tokyo). 2000;40(4):234–8.

33.

Ugarriza LF, Cabezudo JM, Porras LF, Rodríguez-Sánchez JA. Cord compression secondary to cervical disc herniation associated with calcification of the ligamentum flavum: case report. Neurosurgery. 2001;48(3):673–6.

34.

Guesmi H, Lamouchi T, Mlaiki A, Ksira I, Tlili K, Krifa H. Calcification of the cervical ligamentum flavum. Case report and review of the literature. Neurochirurgie. 2005;51(6):591–4 (in French).

35.

Muthukumar N, Karuppaswamy U. Tumoral calcium pyrophosphate dihydrate deposition disease of the ligamentum flavum. Neurosurgery. 2003;53(1):103–8

36.

Yabuki S, Kikuchi S. Endoscopic surgery for cervical myelopathy due to calcification of the ligamentum flavum. J Spinal Disord Tech. 2008;21(7):518–23.

37.

Nagashima C, Takahama M, Shibata T, Nakamura H, Okada K, Morita H, Kubo H. Calcium pyrophosphate dihydrate deposits in the cervical ligamenta flava causing myeloradiculopathy. J Neurosurg. 1984;60(1):69–80

38.

Koyama S, Nishimura T, Kubokura T, Sannoh N, Tsubone K. A case of myelopathy caused by calcified nodules of cervical ligamentum flavum. No Shinkei Geka. 1988;16(10):1179–85 (in Japanese).

Title: Cervical myelopathy due to calcification of the posterior atlantoaxial membrane associated with generalized articular deposition of calcium pyrophosphate dihydrate: a case report and review of the literature
Authors: Kanji Mori
Shinji Imai
Kazuya Nishizawa
Yoshitaka Matsusue
Publication date: 01-11-2015
Publisher: Springer Japan
Published in: Journal of Orthopaedic Science / Issue 6/2015
Print ISSN: 0949-2658
Electronic ISSN: 1436-2023
DOI: https://doi.org/10.1007/s00776-014-0631-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Cervical myelopathy due to calcification of the posterior atlantoaxial membrane associated with generalized articular deposition of calcium pyrophosphate dihydrate: a case report and review of the literature

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 6/2015

Fracture-dislocation of the sacroiliac joint with severely unstable fractures of the pelvis and femur in a 16-month-old patient: a case report

Functional outcome of en bloc excision and custom prosthetic replacement for giant cell tumor of the distal radius

Sonographic evaluation of effects of the volar plate on trigger finger

Comparison of tip apex distance and cut-out complications between helical blades and lag screws in intertrochanteric fractures among the elderly: a meta-analysis

Invasive dumbbell spinal meningiomas: report of four cases and a review of the literature

Hyperamylasemia and pancreatitis following posterior spinal surgery