Skip to main content
Top
Published in: Journal of Orthopaedic Science 5/2011

01-09-2011 | Original Article

Perioperative complications and adverse events after lumbar spinal surgery: evaluation of 1012 operations at a single center

Authors: Shiro Imagama, Noriaki Kawakami, Taichi Tsuji, Tetsuya Ohara, Yuji Matsubara, Tokumi Kanemura, Manabu Goto, Yoshito Katayama, Naoki Ishiguro

Published in: Journal of Orthopaedic Science | Issue 5/2011

Login to get access

Abstract

Background

Lumbar surgery and associated complications are increasing as society is aging. However, definitions of complications after lumbar surgery have not been established and previous reports have varied in the definition of, and focus on, intraoperative or major postoperative complications. We analyzed the frequency and severity of perioperative complications and all minor adverse events in lumbar surgery at a single center.

Methods

We retrospectively reviewed all lumbar surgery, including decompression surgery with or without fusion, at Meijo Hospital over a 10-year period. Perioperative complications and all surgery-related adverse events until 1 month postoperatively were reviewed for 1012 operations on 918 patients (average age 54 years old). The incidence of intraoperative complications was compared between junior (<10 years experience of spine surgery) and senior (≥10 years experience) surgeons.

Results

Perioperative complications and adverse events occurred in 159 operations (15.7%) on 127 patients (13.8%). There were a variety of perioperative adverse events, including digestive problems. Of the 159 complications and events, 24 (2.4%) were intraoperative and 135 (13.3%) were postoperative. Incidence of intraoperative complications was not significantly higher for junior surgeons; however, the operations performed by senior surgeons were significantly more invasive. Complications were more frequent in elderly patients (p < 0.01) and in operations that were longer (p < 0.0001), had greater estimated blood loss (p < 0.0001), and involved use of spinal instrumentation (p < 0.0001). Psychotic symptoms occurred significantly more often in older patients (p < 0.001).

Conclusion

The absence of a relationship between the experience of the surgeon and incidence of intraoperative complications may be because of the greater effect of invasive surgery. Although age and invasiveness were associated with more perioperative adverse events, we do not conclude that major surgery should be avoided for elderly patients. In contrast, careful focus on the surgical indication and procedure is required for these patients.
Literature
1.
go back to reference Abraham DJ, Herkowitz HN, Katz JN. Indications for thoracic and lumbar spine fusion and trends in use. Orthop Clin N Am. 1998;29:803.CrossRef Abraham DJ, Herkowitz HN, Katz JN. Indications for thoracic and lumbar spine fusion and trends in use. Orthop Clin N Am. 1998;29:803.CrossRef
2.
go back to reference Deyo RA, Mirza SK. Trends and variations in the use of spine surgery. Clin Orthop Relat Res. 2006;443:139–46.PubMedCrossRef Deyo RA, Mirza SK. Trends and variations in the use of spine surgery. Clin Orthop Relat Res. 2006;443:139–46.PubMedCrossRef
3.
go back to reference Gray DT, Deyo RA, Kreuter W, Mirza SK, Heagerty PJ, Comstock BA, Chan L. Population-based trends in volumes and rates of ambulatory lumbar spine surgery. Spine. 2006;31:1957–63. (discussion 64).PubMedCrossRef Gray DT, Deyo RA, Kreuter W, Mirza SK, Heagerty PJ, Comstock BA, Chan L. Population-based trends in volumes and rates of ambulatory lumbar spine surgery. Spine. 2006;31:1957–63. (discussion 64).PubMedCrossRef
4.
go back to reference Weinstein JN, Lurie JD, Olson PR, Bronner KK, Fisher ES. United States’ trends and regional variations in lumbar spine surgery: 1992–2003. Spine. 2006;31:2707–14.PubMed Weinstein JN, Lurie JD, Olson PR, Bronner KK, Fisher ES. United States’ trends and regional variations in lumbar spine surgery: 1992–2003. Spine. 2006;31:2707–14.PubMed
5.
go back to reference Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205–13.PubMedCrossRef Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205–13.PubMedCrossRef
6.
go back to reference Mirza SK, Deyo RA, Heagerty PJ, Turner JA, Lee LA, Goodkin R. Towards standardized measurement of adverse events in spine surgery: conceptual model and pilot evaluation. BMC Musculoskelet Disord. 2006;7:53.PubMedCrossRef Mirza SK, Deyo RA, Heagerty PJ, Turner JA, Lee LA, Goodkin R. Towards standardized measurement of adverse events in spine surgery: conceptual model and pilot evaluation. BMC Musculoskelet Disord. 2006;7:53.PubMedCrossRef
7.
go back to reference Patel N, Bagan B, Vadera S, Maltenfort MG, Deutsch H, Vaccaro AR, Harrop J, Sharan A, Ratliff JK. Obesity and spine surgery: relation to perioperative complications. J Neurosurg Spine. 2007;6:291–7.PubMedCrossRef Patel N, Bagan B, Vadera S, Maltenfort MG, Deutsch H, Vaccaro AR, Harrop J, Sharan A, Ratliff JK. Obesity and spine surgery: relation to perioperative complications. J Neurosurg Spine. 2007;6:291–7.PubMedCrossRef
8.
go back to reference Acosta FL, Cloyd JM, Aryan HE, Ames CP. Perioperative complications and clinical outcomes of multilevel circumferential lumbar spinal fusion in the elderly. J Clin Neurosci. 2009;16:69–73.PubMedCrossRef Acosta FL, Cloyd JM, Aryan HE, Ames CP. Perioperative complications and clinical outcomes of multilevel circumferential lumbar spinal fusion in the elderly. J Clin Neurosci. 2009;16:69–73.PubMedCrossRef
9.
go back to reference Faciszewski T, Winter RB, Lonstein JE, Denis F, Johnson L. The surgical and medical perioperative complications of anterior spinal fusion surgery in the thoracic and lumbar spine in adults. A review of 1223 procedures. Spine. 1995;20:1592–9.PubMedCrossRef Faciszewski T, Winter RB, Lonstein JE, Denis F, Johnson L. The surgical and medical perioperative complications of anterior spinal fusion surgery in the thoracic and lumbar spine in adults. A review of 1223 procedures. Spine. 1995;20:1592–9.PubMedCrossRef
10.
go back to reference Faundez AA, Schwender JD, Safriel Y, Gilbert TJ, Mehbod AA, Denis F, Transfeldt EE, Wroblewski JM. Clinical and radiological outcome of anterior–posterior fusion versus transforaminal lumbar interbody fusion for symptomatic disc degeneration: a retrospective comparative study of 133 patients. Eur Spine J. 2009;18:203–11.PubMedCrossRef Faundez AA, Schwender JD, Safriel Y, Gilbert TJ, Mehbod AA, Denis F, Transfeldt EE, Wroblewski JM. Clinical and radiological outcome of anterior–posterior fusion versus transforaminal lumbar interbody fusion for symptomatic disc degeneration: a retrospective comparative study of 133 patients. Eur Spine J. 2009;18:203–11.PubMedCrossRef
11.
go back to reference Glassman SD, Alegre G, Carreon L, Dimar JR, Johnson JR. Perioperative complications of lumbar instrumentation and fusion in patients with diabetes mellitus. Spine J. 2003;3:496–501.PubMedCrossRef Glassman SD, Alegre G, Carreon L, Dimar JR, Johnson JR. Perioperative complications of lumbar instrumentation and fusion in patients with diabetes mellitus. Spine J. 2003;3:496–501.PubMedCrossRef
12.
go back to reference Deyo RA, Cherkin DC, Loeser JD, Bigos SJ, Ciol MA. Morbidity and mortality in association with operations on the lumbar spine. The influence of age, diagnosis, and procedure. J Bone Jt Surg Am. 1992;74:536–43. Deyo RA, Cherkin DC, Loeser JD, Bigos SJ, Ciol MA. Morbidity and mortality in association with operations on the lumbar spine. The influence of age, diagnosis, and procedure. J Bone Jt Surg Am. 1992;74:536–43.
13.
go back to reference Deyo RA, Ciol MA, Cherkin DC, Loeser JD, Bigos SJ. Lumbar spinal fusion. A cohort study of complications, reoperations, and resource use in the Medicare population. Spine. 1993;18:1463–70.PubMed Deyo RA, Ciol MA, Cherkin DC, Loeser JD, Bigos SJ. Lumbar spinal fusion. A cohort study of complications, reoperations, and resource use in the Medicare population. Spine. 1993;18:1463–70.PubMed
14.
go back to reference Deyo RA, Nachemson A, Mirza SK. Spinal-fusion surgery—the case for restraint. N Engl J Med. 2004;350:722–6.PubMedCrossRef Deyo RA, Nachemson A, Mirza SK. Spinal-fusion surgery—the case for restraint. N Engl J Med. 2004;350:722–6.PubMedCrossRef
15.
go back to reference Campbell PG, Malone J, Yadla S, Maltenfort MG, Harrop JS, Sharan AD, Ratliff JK. Early complications related to approach in thoracic and lumbar spine surgery: a single center prospective study. World Neurosurg. 2010;73:395–401.PubMedCrossRef Campbell PG, Malone J, Yadla S, Maltenfort MG, Harrop JS, Sharan AD, Ratliff JK. Early complications related to approach in thoracic and lumbar spine surgery: a single center prospective study. World Neurosurg. 2010;73:395–401.PubMedCrossRef
16.
go back to reference Knight RQ, Schwaegler P, Hanscom D, Roh J. Direct lateral lumbar interbody fusion for degenerative conditions: early complication profile. J Spinal Disord Tech. 2009;22:34–7.PubMedCrossRef Knight RQ, Schwaegler P, Hanscom D, Roh J. Direct lateral lumbar interbody fusion for degenerative conditions: early complication profile. J Spinal Disord Tech. 2009;22:34–7.PubMedCrossRef
17.
go back to reference Yadla S, Malone J, Campbell PG, Nasser R, Maltenfort MG, Harrop JS, Sharan AD, Ratliff JK. Incidence of early complications in cervical spine surgery and relation to preoperative diagnosis: a single-center prospective study. J Spinal Disord Tech. 2011;24:50–4.PubMedCrossRef Yadla S, Malone J, Campbell PG, Nasser R, Maltenfort MG, Harrop JS, Sharan AD, Ratliff JK. Incidence of early complications in cervical spine surgery and relation to preoperative diagnosis: a single-center prospective study. J Spinal Disord Tech. 2011;24:50–4.PubMedCrossRef
18.
go back to reference Grob D, Mannion AF. The patient’s perspective on complications after spine surgery. Eur Spine J. 2009;18(Suppl 3):380–5.PubMedCrossRef Grob D, Mannion AF. The patient’s perspective on complications after spine surgery. Eur Spine J. 2009;18(Suppl 3):380–5.PubMedCrossRef
19.
go back to reference Ratliff JK, Lebude B, Albert T, Anene-Maidoh T, Anderson G, Dagostino P, Maltenfort M, Hilibrand A, Sharan A, Vaccaro AR. Complications in spinal surgery: comparative survey of spine surgeons and patients who underwent spinal surgery. J Neurosurg Spine. 2009;10:578–84.PubMedCrossRef Ratliff JK, Lebude B, Albert T, Anene-Maidoh T, Anderson G, Dagostino P, Maltenfort M, Hilibrand A, Sharan A, Vaccaro AR. Complications in spinal surgery: comparative survey of spine surgeons and patients who underwent spinal surgery. J Neurosurg Spine. 2009;10:578–84.PubMedCrossRef
20.
go back to reference Carreon LY, Puno RM, Dimar JR 2nd, Glassman SD, Johnson JR. Perioperative complications of posterior lumbar decompression and arthrodesis in older adults. J Bone Jt Surg Am. 2003;85-A:2089–92. Carreon LY, Puno RM, Dimar JR 2nd, Glassman SD, Johnson JR. Perioperative complications of posterior lumbar decompression and arthrodesis in older adults. J Bone Jt Surg Am. 2003;85-A:2089–92.
21.
go back to reference Jackson RP, McManus AC. The iliac buttress. A computed tomographic study of sacral anatomy. Spine. 1993;18:1318–28.PubMedCrossRef Jackson RP, McManus AC. The iliac buttress. A computed tomographic study of sacral anatomy. Spine. 1993;18:1318–28.PubMedCrossRef
22.
go back to reference Kostuik JP, Valdevit A, Chang HG, Kanzaki K. Biomechanical testing of the lumbosacral spine. Spine. 1998;23:1721–8.PubMedCrossRef Kostuik JP, Valdevit A, Chang HG, Kanzaki K. Biomechanical testing of the lumbosacral spine. Spine. 1998;23:1721–8.PubMedCrossRef
23.
go back to reference Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for prevention of surgical site infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee. Am J Infect Control. 1999;27:97–132. (quiz 3–4; discussion 96).PubMedCrossRef Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for prevention of surgical site infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee. Am J Infect Control. 1999;27:97–132. (quiz 3–4; discussion 96).PubMedCrossRef
24.
go back to reference Kanayama M, Hashimoto T, Shigenobu K, Oha F, Togawa D. Effective prevention of surgical site infection using a Centers for Disease Control and Prevention guideline-based antimicrobial prophylaxis in lumbar spine surgery. J Neurosurg Spine. 2007;6:327–9.PubMedCrossRef Kanayama M, Hashimoto T, Shigenobu K, Oha F, Togawa D. Effective prevention of surgical site infection using a Centers for Disease Control and Prevention guideline-based antimicrobial prophylaxis in lumbar spine surgery. J Neurosurg Spine. 2007;6:327–9.PubMedCrossRef
25.
go back to reference Edwards JR, Peterson KD, Andrus ML, Dudeck MA, Pollock DA, Horan TC. National Healthcare Safety Network (NHSN) report, data summary for 2006 through 2007, issued November 2008. Am J Infect Control. 2008;36:609–26.PubMedCrossRef Edwards JR, Peterson KD, Andrus ML, Dudeck MA, Pollock DA, Horan TC. National Healthcare Safety Network (NHSN) report, data summary for 2006 through 2007, issued November 2008. Am J Infect Control. 2008;36:609–26.PubMedCrossRef
26.
go back to reference Bono CM, Watters WC 3rd, Heggeness MH, Resnick DK, Shaffer WO, Baisden J, Ben-Galim P, Easa JE, Fernand R, Lamer T, Matz PG, Mendel RC, Patel RK, Reitman CA, Toton JF. An evidence-based clinical guideline for the use of antithrombotic therapies in spine surgery. Spine J. 2009;9:1046–51.PubMedCrossRef Bono CM, Watters WC 3rd, Heggeness MH, Resnick DK, Shaffer WO, Baisden J, Ben-Galim P, Easa JE, Fernand R, Lamer T, Matz PG, Mendel RC, Patel RK, Reitman CA, Toton JF. An evidence-based clinical guideline for the use of antithrombotic therapies in spine surgery. Spine J. 2009;9:1046–51.PubMedCrossRef
Metadata
Title
Perioperative complications and adverse events after lumbar spinal surgery: evaluation of 1012 operations at a single center
Authors
Shiro Imagama
Noriaki Kawakami
Taichi Tsuji
Tetsuya Ohara
Yuji Matsubara
Tokumi Kanemura
Manabu Goto
Yoshito Katayama
Naoki Ishiguro
Publication date
01-09-2011
Publisher
Springer Japan
Published in
Journal of Orthopaedic Science / Issue 5/2011
Print ISSN: 0949-2658
Electronic ISSN: 1436-2023
DOI
https://doi.org/10.1007/s00776-011-0123-6

Other articles of this Issue 5/2011

Journal of Orthopaedic Science 5/2011 Go to the issue