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01-12-2018 | Psychiatry and Preclinical Psychiatric Studies - Short communication

Desacylghrelin but not acylghrelin is reduced during smoking cessation

Authors: Mahsa Ardeshiripur, Mathias Rhein, Helge Frieling, Stefan Bleich, Thomas Hillemacher, Marc Muschler, Alexander Glahn

Published in: Journal of Neural Transmission | Issue 12/2018

Abstract

This study focused on the acetylation status of ghrelin examining acyl- and desacylghrelin and its effect on craving during 14 days of smoking abstinence. This is the first study demonstrating changes in desacylghrelin plasma levels in smokers compared to non-smokers while there was no difference of acylated ghrelin. Future studies should specifically refer to plasma ghrelin as either desacyl- or acylghrelin since both have different effects on tobacco-seeking behavior and the underlying physiology.

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Title: Desacylghrelin but not acylghrelin is reduced during smoking cessation
Authors: Mahsa Ardeshiripur
Mathias Rhein
Helge Frieling
Stefan Bleich
Thomas Hillemacher
Marc Muschler
Alexander Glahn
Publication date: 01-12-2018
Publisher: Springer Vienna
Published in: Journal of Neural Transmission / Issue 12/2018
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-018-1930-0

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Desacylghrelin but not acylghrelin is reduced during smoking cessation

Abstract

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