Top

Published in:

Open Access 01-02-2017 | High Impact Review in Neuroscience, Neurology or Psychiatry - Review Article

Structural brain imaging correlates of ASD and ADHD across the lifespan: a hypothesis-generating review on developmental ASD–ADHD subtypes

Authors: Nanda Rommelse, Jan K. Buitelaar, Catharina A. Hartman

Published in: Journal of Neural Transmission | Issue 2/2017

Abstract

We hypothesize that it is plausible that biologically distinct developmental ASD–ADHD subtypes are present, each characterized by a distinct time of onset of symptoms, progression and combination of symptoms. The aim of the present narrative review was to explore if structural brain imaging studies may shed light on key brain areas that are linked to both ASD and ADHD symptoms and undergo significant changes during development. These findings may possibly pinpoint to brain mechanisms underlying differential developmental ASD–ADHD subtypes. To this end we brought together the literature on ASD and ADHD structural brain imaging symptoms and particularly highlight the adolescent years and beyond. Findings indicate that the vast majority of existing MRI studies has been cross-sectional and conducted in children, and sometimes did include adolescents as well, but without explicitly documenting on this age group. MRI studies documenting on age effects in adults with ASD and/or ADHD are rare, and if age is taken into account, only linear effects are examined. Data from various studies suggest that a crucial distinctive feature underlying different developmental ASD–ADHD subtypes may be the differential developmental thinning patterns of the anterior cingulate cortex and related connections towards other prefrontal regions. These regions are crucial for the development of cognitive/effortful control and socio-emotional functioning, with impairments in these features as key to both ASD and ADHD.

Agnew-Blais JC, Polanczyk GV, Danese A, Wertz J, Moffitt TE, Arseneault L (2016) Evaluation of the persistence, remission, and emergence of attention-deficit/hyperactivity disorder in young adulthood. JAMA Psychiatry. 73(7):713–720PubMedCrossRef

Alahyane N, Brien DC, Coe BC, Stroman PW, Munoz DP (2014) Developmental improvements in voluntary control of behavior: effect of preparation in the fronto-parietal network? Neuroimage. 98:103–117PubMedCrossRef

Almeida LG, Ricardo-Garcell J, Prado H, Barajas L, Fernández-Bouzas A, Avila D, Martínez RB (2010) Reduced right frontal cortical thickness in children, adolescents and adults with ADHD and its correlation to clinical variables: a cross-sectional study. J Psychiatr Res 4(16):1214–1223CrossRef

Arbabshirani MR, Plis S, Sui J, Calhoun VD (2016) Single subject prediction of brain disorders in neuroimaging: Promises and pitfalls. Neuroimage. doi:10.1016/j.neuroimage.2016.02.079

Brieber S, Neufang S, Bruning N, Kamp-Becker I, Remschmidt H, Herpertz-Dahlmann B, Fink GR, Konrad K (2007) Structural brain abnormalities in adolescents with autism spectrum disorder and patients with attention deficit/hyperactivity disorder. J Child Psychol Psychiatry 48(12):1251–1258PubMedCrossRef

Cachia A, Borst G, Tissier C, Fisher C, Plaze M, Gay O, Rivière D, Gogtay N, Giedd J, Mangin JF, Houdé O, Raznahan A (2016) Longitudinal stability of the folding pattern of the anterior cingulate cortex during development. Dev Cogn Neurosci 19:122–127PubMedCrossRef

Casey BJ, Jones RM, Levita L, Libby V, Pattwell SS, Ruberry EJ, Soliman F, Somerville LH (2010) The storm and stress of adolescence: insights from human imaging and mouse genetics. Dev Psychobiol 52(3):225–235PubMedPubMedCentral

Caye A, Rocha TB, Anselmi L, Murray J, Menezes AM, Barros FC, Gonçalves H, Wehrmeister F, Jensen CM, Steinhausen HC, Swanson JM, Kieling C, Rohde LA (2016) Attention-deficit/hyperactivity disorder trajectories from childhood to young adulthood: evidence from a birth cohort supporting a late-onset syndrome. JAMA Psychiatry. 73(7):705–712PubMedCrossRef

Christakou A, Murphy CM, Chantiluke K, Cubillo AI, Smith AB, Giampietro V, Daly E, Ecker C, Robertson D, MRC AIMS consortium, Murphy DG, Rubia K (2013) Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with autism. Mol Psychiatry 18(2):236–244PubMedCrossRef

Cortese S, Kelly C, Chabernaud C, Proal E, Di Martino A, Milham MP, Castellanos FX (2012) Toward systems neuroscience of ADHD: a meta-analysis of 55 fMRI studies. Am J Psychiatry 169(10):1038–1055PubMedCrossRef

Courchesne E, Campbell K, Solso S (2011) Brain growth across the life span in autism: age-specific changes in anatomical pathology. Brain Res 1380:138–145PubMedCrossRef

Davenport ND, Karatekin C, White T, Lim KO (2010) Differential fractional anisotropy abnormalities in adolescents with ADHD or schizophrenia. Psychiatry Res 181(3):193–198PubMedPubMedCentralCrossRef

Doherty JL, Owen MJ (2014) Genomic insights into the overlap between psychiatric disorders: implications for research and clinical practice. Genome Med. 6:29PubMedPubMedCentralCrossRef

Dougherty CC, Evans DW, Myers SM, Moore GJ, Michael AM (2016) A comparison of structural brain imaging findings in autism spectrum disorder and attention-deficit hyperactivity disorder. Neuropsychol Rev 26(1):25–43PubMedCrossRef

Draganski B, Lutti A, Kherif F (2013) Impact of brain aging and neurodegeneration on cognition: evidence from MRI. Curr Opin Neurol 26(6):640–645PubMedCrossRef

Ducharme S, Hudziak JJ, Botteron KN, Albaugh MD, Nguyen TV, Karama S et al (2012) Decreased regional cortical thickness and thinning rate are associated with inattention symptoms in healthy children. J Am Acad Child Adolesc Psychiatry 51(1):18–27PubMedCrossRef

Duerden EG, Mak-Fan KM, Taylor MJ, Roberts SW (2012) Regional differences in grey and white matter in children and adults with autism spectrum disorders: an activation likelihood estimate (ALE) meta-analysis. Autism Res. 5(1):49–66PubMedCrossRef

Ecker C, Bookheimer SY, Murphy DG (2015) Neuroimaging in autism spectrum disorder: brain structure and function across the lifespan. Lancet Neurol 14(11):1121–1134PubMedCrossRef

Edlow AG (2016) Maternal obesity and neurodevelopmental and psychiatric disorders in offspring. Prenat Diagn. doi:10.1002/pd.4932

Fine JG, Musielak KA, Semrud-Clikeman M (2014) Smaller splenium in children with nonverbal learning disability compared to controls, high-functioning autism and ADHD. Child Neuropsychol. 20(6):641–661PubMedCrossRef

Fluegge K (2016) Does environmental exposure to the greenhouse gas, N2O, contribute to etiological factors in neurodevelopmental disorders? A mini-review of the evidence. Environ Toxicol Pharmacol 47:6–18PubMedCrossRef

Francx W, Zwiers MP, Mennes M, Oosterlaan J, Heslenfeld D, Hoekstra PJ et al (2015) White matter microstructure and developmental improvement of hyperactive/impulsive symptoms in attention-deficit/hyperactivity disorder. J Child Psychol Psychiatry 56(12):1289–1297PubMedPubMedCentralCrossRef

Francx W, Llera A, Mennes M, Zwiers MP, Faraone SV, Oosterlaan J, Heslenfeld D, Hoekstra PJ, Hartman CA, Franke B, Buitelaar JK, Beckmann CF (2016) Integrated analysis of gray and white matter alterations in attention-deficit/hyperactivity disorder. Neuroimage Clin. 11:357–367PubMedPubMedCentralCrossRef

Galvan A, Hare TA, Parra CE, Penn J, Voss H, Glover G, Casey BJ (2006) Earlier development of the accumbens relative to orbitofrontal cortex might underlie risk-taking behavior in adolescents. J Neurosci 26(25):6885–6892PubMedCrossRef

Galvan A, Hare T, Voss H, Glover G, Casey BJ (2007) Risk-taking and the adolescent brain: who is at risk? Dev Sci. 10(2):F8–F14PubMedCrossRef

Gariépy JF, Watson KK, Du E, Xie DL, Erb J, Amasino D, Platt ML (2014) Social learning in humans and other animals. Front Neurosci. 8:58PubMedPubMedCentral

Geurts HM, Ridderinkhof KR, Scholte HS (2013) The relationship between grey-matter and ASD and ADHD traits in typical adults. J Autism Dev Disord 43(7):1630–1641PubMedCrossRef

Giedd JN, Raznahan A, Alexander-Bloch A, Schmitt E, Gogtay N, Rapoport JL (2015) Child psychiatry branch of the National Institute of Mental Health longitudinal structural magnetic resonance imaging study of human brain development. Neuropsychopharmacology. 40(1):43–49PubMedCrossRef

Greven CU, Asherson P, Rijsdijk FV, Plomin R (2011) A longitudinal twin study on the association between inattentive and hyperactive-impulsive ADHD symptoms. J Abnorm Child Psychol 39(5):623–632PubMedCrossRef

Greven CU, Bralten J, Mennes M, O’Dwyer L, van Hulzen KJ, Rommelse N et al (2015) Developmentally stable whole-brain volume reductions and developmentally sensitive caudate and putamen volume alterations in those with attention-deficit/hyperactivity disorder and their unaffected siblings. JAMA Psychiatry. 72(5):490–499PubMedCrossRef

Hartman CA, Geurts HM, Franke B, Buitelaar JK, Rommelse NN (2016) Changing ASD-ADHD symptom co-occurrence across the lifespan with adolescence as crucial time window: Illustrating the need to go beyond childhood. Neurosci Biobehav Rev 71:529–541PubMedCrossRef

Hedman AM, van Haren NE, Schnack HG, Kahn RS, Hulshoff Pol HE (2012) Human brain changes across the life span: a review of 56 longitudinal magnetic resonance imaging studies. Hum Brain Mapp 33(8):1987–2002PubMedCrossRef

Henstridge CM, Jackson RJ, Kim JM, Herrmann AG, Wright AK, Harris SE et al (2015) Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse. Acta Neuropathol Commun. 3:53PubMedPubMedCentralCrossRef

Homberg JR, Kyzar EJ, Scattoni ML, Norton WH, Pittman J, Gaikwad S, Nguyen M, Poudel MK, Ullmann JF, Diamond DM, Kaluyeva AA, Parker MO, Brown RE, Song C, Gainetdinov RR, Gottesman II, Kalueff AV (2016) Genetic and environmental modulation of neurodevelopmental disorders: translational insights from labs to beds. Brain Res Bull 125:79–91PubMedCrossRef

Ismail MM, Keynton RS, Mostapha MM, ElTanboly AH, Casanova MF, Gimel’farb GL, El-Baz A (2016) Studying autism spectrum disorder with structural and diffusion magnetic resonance imaging: a survey. Front Hum Neurosci. 10:211PubMedPubMedCentralCrossRef

Itahashi T, Yamada T, Nakamura M, Watanabe H, Yamagata B, Jimbo D, Shioda S, Kuroda M, Toriizuka K, Kato N, Hashimoto R (2014) Linked alterations in gray and white matter morphology in adults with high-functioning autism spectrum disorder: a multimodal brain imaging study. Neuroimage Clin. 7:155–169PubMedPubMedCentralCrossRef

Jansen A, Mous SE, White T, Posthuma D, Polderman TJ (2015) What twin studies tell us about the heritability of brain development, morphology, and function: a review. Neuropsychol Rev 25(1):27–46PubMedPubMedCentralCrossRef

Jensen CM, Steinhausen HC (2015) Comorbid mental disorders in children and adolescents with attention-deficit/hyperactivity disorder in a large nationwide study. Atten Deficit Hyperact Disord 7(1):27–38CrossRef

Johnson MH, Gliga T, Jones E, Charman T (2015) Annual research review: infant development, autism, and ADHD—early pathways to emerging disorders. J Child Psychol Psychiatry 56(3):228–247PubMedCrossRef

Kasparek T, Theiner P, Filova A (2015) Neurobiology of ADHD from childhood to adulthood: findings of imaging methods. J Atten Disord. 19(11):931–943PubMedCrossRef

Khundrakpam BS, Reid A, Brauer J, Carbonell F, Lewis J, Ameis S, Karama S, Lee J, Chen Z, Das S, Evans AC, Brain Development Cooperative Group (2013) Developmental changes in organization of structural brain networks. Cereb Cortex 23(9):2072–2085PubMedCrossRef

Khundrakpam BS, Tohka J, Evans AC, Brain Development Cooperative Group (2015) Prediction of brain maturity based on cortical thickness at different spatial resolutions. Neuroimage 111:350–359PubMedCrossRef

Kleibeuker SW, De Dreu CK, Crone EA (2013) The development of creative cognition across adolescence: distinct trajectories for insight and divergent thinking. Dev Sci. 16(1):2–12PubMedCrossRef

Kleinhans NM, Pauley G, Richards T, Neuhaus E, Martin N, Corrigan NM et al (2012) Age-related abnormalities in white matter microstructure in autism spectrum disorders. Brain Res 2012(1479):1–16CrossRef

Koolschijn PC, Geurts HM, van der Leij AR, Scholte HS (2015) Are autistic traits in the general population related to global and regional brain differences? J Autism Dev Disord 45(9):2779–2791PubMedPubMedCentralCrossRef

Lange N, Travers BG, Bigler ED, Prigge MB, Froehlich AL, Nielsen JA et al (2015) Longitudinal volumetric brain changes in autism spectrum disorder ages 6–35 years. Autism Res. 8(1):82–93PubMedCrossRef

Lebel C, Beaulieu C (2011) Longitudinal development of human brain wiring continues from childhood into adulthood. J Neurosci 31:10937–10947PubMedCrossRef

Lefebvre A, Beggiato A, Bourgeron T, Toro R (2015) Neuroanatomical diversity of corpus callosum and brain volume in autism: meta-analysis, analysis of the autism brain imaging data exchange project, and simulation. Biol Psychiatry 78(2):126–134PubMedCrossRef

Lenroot RK, Gogtay N, Greenstein DK, Wells EM, Wallace GL, Clasen LS, Blumenthal JD, Lerch J, Zijdenbos AP, Evans AC, Thompson PM, Giedd JN (2007) Sexual dimorphism of brain developmental trajectories during childhood and adolescence. Neuroimage 36:1065–1073PubMedPubMedCentralCrossRef

Lenroot RK, Schmitt JE, Ordaz SJ, Wallace GL, Neale MC, Lerch JP et al (2009) Differences in genetic and environmental influences on the human cerebral cortex associated with development during childhood and adolescence. Hum Brain Mapp 30:163–174PubMedCrossRef

Lim L, Marquand A, Cubillo AA, Smith AB, Chantiluke K, Simmons A, Mehta M, Rubia K (2013) Disorder-specific predictive classification of adolescents with attention deficit hyperactivity disorder (ADHD) relative to autism using structural magnetic resonance imaging. PLoS One 8(5):e63660PubMedPubMedCentralCrossRef

Lim L, Chantiluke K, Cubillo AI, Smith AB, Simmons A, Mehta MA, Rubia K (2015) Disorder-specific grey matter deficits in attention deficit hyperactivity disorder relative to autism spectrum disorder. Psychol Med 45(5):965–976PubMedCrossRef

Lincoln SH, Hooker CI (2014) Neural structure and social dysfunction in individuals at clinical high risk for psychosis. Psychiatry Res 224(3):152–158PubMedCrossRef

Luby J, Belden A, Botteron K, Marrus N, Harms MP, Babb C et al (2013) The effects of poverty on childhood brain development: the mediating effect of caregiving and stressful life events. JAMA Pediatr. 167(12):1135–1142PubMedPubMedCentralCrossRef

Luciana M, Collins PF, Muetzel RL, Lim KO (2013) Effects of alcohol use initiation on brain structure in typically developing adolescents. Am J Drug Alcohol Abuse 39(6):345–355PubMedPubMedCentralCrossRef

Luders E, Kurth F, Das D, Oyarce DE, Shaw ME, Sachdev P, Easteal S, Anstey KJ, Cherbuin N (2016) Associations between corpus callosum size and ADHD symptoms in older adults: the PATH through life study. Psychiatry Res 256:8–14PubMedCrossRef

Lundström S, Reichenberg A, Anckarsäter H, Lichtenstein P, Gillberg C (2015) Autism phenotype versus registered diagnosis in Swedish children: prevalence trends over 10 years in general population samples. BMJ 350:h1961PubMedPubMedCentralCrossRef

Lupien SJ, McEwen BS, Gunnar MR, Heim C (2009) Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci 10(6):434–445PubMedCrossRef

Mackie S, Shaw P, Lenroot R, Pierson R, Greenstein DK, Nugent TF 3rd, Sharp WS et al (2007) Cerebellar development and clinical outcome in attention deficit hyperactivity disorder. Am J Psychiatry 164(4):647–655PubMedCrossRef

Marquand AF, Rezek I, Buitelaar J, Beckmann CF (2016a) Understanding heterogeneity in clinical cohorts using normative models: beyond case-control studies. Biol Psychiatry 80(7):552–561PubMedPubMedCentralCrossRef

Marquand AF, Wolfers T, Mennes M, Buitelaar J, Beckmann CF (2016b) Beyond lumping and splitting: a review of computational approaches for stratifying psychiatric disorders. Biol Psychiatry Cogn Neurosci Neuroimaging. 1(5):433–447PubMedPubMedCentralCrossRef

Mayne BT, Bianco-Miotto T, Buckberry S, Breen J, Clifton V, Shoubridge C, Roberts CT (2016) Large scale gene expression meta-analysis reveals tissue-specific, sex-biased gene expression in humans. Front Genet. 7:183PubMedPubMedCentralCrossRef

McCarthy H, Skokauskas N, Frodl T (2014) Identifying a consistent pattern of neural function in attention deficit hyperactivity disorder: a meta-analysis. Psychol Med 44(4):869–880PubMedCrossRef

Ment LR, Kesler S, Vohr B, Katz KH, Baumgartner H, Schneider KC, Delancy S, Silbereis J, Duncan CC, Constable RT, Makuch RW, Reiss AL (2009) Longitudinal brain volume changes in preterm and term control subjects during late childhood and adolescence. Pediatrics 123:503–511PubMedPubMedCentralCrossRef

Mills KL, Tamnes CK (2014) Methods and considerations for longitudinal structural brain imaging analysis across development. Dev Cogn Neurosci 9:172–190PubMedCrossRef

Mills KL, Goddings AL, Clasen LS, Giedd JN, Blakemore SJ (2014) The developmental mismatch in structural brain maturation during adolescence. Dev Neurosci 36(3–4):147–160PubMedCrossRef

Moffitt TE, Houts R, Asherson P, Belsky DW, Corcoran DL, Hammerle M et al (2015) Is adult ADHD a childhood-onset neurodevelopmental disorder? Evidence from a four-decade longitudinal cohort study. Am J Psychiatry 172(10):967–977PubMedPubMedCentralCrossRef

O’Dwyer L, Tanner C, van Dongen EV, Greven CU, Bralten J, Zwiers MP et al (2014) Brain volumetric correlates of autism spectrum disorder symptoms in attention deficit/hyperactivity disorder. PLoS One 9(6):e101130PubMedPubMedCentralCrossRef

O’Dwyer L, Tanner C, van Dongen EV, Greven CU, Bralten J, Zwiers MP, Franke B, Heslenfeld D, Oosterlaan J, Hoekstra PJ, Hartman CA, Groen W, Rommelse N, Buitelaar JK (2016) Decreased left caudate volume is associated with increased severity of autistic-like symptoms in a Cohort of ADHD patients and their unaffected siblings. PLoS One 11(11):e0165620PubMedPubMedCentralCrossRef

Ordaz SJ, Foran W, Velanova K, Luna B (2013) Longitudinal growth curves of brain function underlying inhibitory control through adolescence. J Neurosci 33(46):18109–18124PubMedPubMedCentralCrossRef

Patriquin MA, DeRamus T, Libero LE, Laird A, Kana RK (2016) Neuroanatomical and neurofunctional markers of social cognition in autism spectrum disorder. Hum Brain Mapp 37(11):3957–3978PubMedCrossRef

Peters S, Van Duijvenvoorde AC, Koolschijn PC, Crone EA (2016) Longitudinal development of frontoparietal activity during feedback learning: contributions of age, performance, working memory and cortical thickness. Dev Cogn Neurosci 19:211–222PubMedPubMedCentralCrossRef

Philip RC, Dauvermann MR, Whalley HC, Baynham K, Lawrie SM, Stanfield AC (2012) A systematic review and meta-analysis of the fMRI investigation of autism spectrum disorders. Neurosci Biobehav Rev 36(2):901–942PubMedCrossRef

Picci G, Scherf KS (2015) A two-hit model of autism: adolescence as the second hit. Clin Psychol Sci. 3(3):349–371PubMedCrossRef

Pingault JB, Viding E, Galéra C, Greven CU, Zheng Y, Plomin R, Rijsdijk F (2015) Genetic and environmental influences on the developmental course of attention-deficit/hyperactivity disorder symptoms from childhood to adolescence. JAMA Psychiatry. 72(7):651–658PubMedCrossRef

Pinto R, Rijsdijk F, Ronald A, Asherson P, Kuntsi J (2016) The genetic overlap of attention-deficit/hyperactivity disorder and autistic-like traits: an investigation of individual symptom scales and cognitive markers. J Abnorm Child Psychol 44(2):335–345PubMedCrossRef

Polderman TJ, Hoekstra RA, Posthuma D, Larsson H (2014) The co-occurrence of autistic and ADHD dimensions in adults: an etiological study in 17,770 twins. Transl Psychiatry. 4:e435PubMedPubMedCentralCrossRef

Proal E, Reiss PT, Klein RG, Mannuzza S, Gotimer K, Ramos-Olazagasti MA et al (2011) Brain gray matter deficits at 33-year follow-up in adults with attention-deficit/hyperactivity disorder established in childhood. Arch Gen Psychiatry 68(11):1122–1134PubMedPubMedCentralCrossRef

Raznahan A, Lee NR, Greenstein D, Wallace GL, Blumenthal JD, Clasen LS, Giedd JN (2016) Globally divergent but locally convergent X- and Y-chromosome influences on cortical development. Cereb Cortex 26(1):70–79PubMedCrossRef

Rommelse NN, Hartman CA (2016) Review: changing (shared) heritability of ASD and ADHD across the lifespan. Eur Child Adolesc Psychiatry 25(3):213–215PubMedCrossRef

Rommelse NN, Franke B, Geurts H, Hartman CA, Buitelaar JK (2010) Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder. Eur Child Adolesc Psychiatry 19:281–295PubMedPubMedCentralCrossRef

Rommelse NN, Geurts HM, Franke B, Buitelaar JK, Hartman CA (2011) A review on cognitive and brain endophenotypes that may be common in autism spectrum disorder and attention-deficit/hyperactivity disorder and facilitate the search for pleiotropic genes. Neurosci Biobehav Rev 35:1363–1396PubMedCrossRef

Ronald A, Hoekstra RA (2011) Autism spectrum disorders and autistic traits: a decade of new twin studies. Am J Med Gen B: Neuropsych Gen. 156:255–274CrossRef

Ronald A, Larsson H, Anckarsäter H, Lichtenstein P (2014) Symptoms of autism and ADHD: a Swedish twin study examining their overlap. J Abnorm Psychol 123(2):440–451PubMedCrossRef

Sacco R, Gabriele S, Persico AM (2015) Head circumference and brain size in autism spectrum disorder: a systematic review and meta-analysis. Psychiatry Res 234(2):239–251PubMedCrossRef

Saitoh O, Karns CM, Courchesne E (2001) Development of the hippocampal formation from 2 to 42 years: mRI evidence of smaller area dentata in autism. Brain. 124(Pt 7):1317–1324PubMedCrossRef

Scheinost D, Sinha R, Cross SN, Kwon SH, Sze G, Constable RT, Ment LR (2016) Does prenatal stress alter the developing connectome? Pediatr Res. doi:10.1038/pr.2016.197

Schmitt JE, Neale MC, Fassassi B, Perez J, Lenroot RK, Wells EM, Giedd JN (2014) The dynamic role of genetics on cortical patterning during childhood and adolescence. Proc Natl Acad Sci USA 111(18):6774–6779PubMedPubMedCentralCrossRef

Schumann CM, Hamstra J, Goodlin-Jones BL, Lotspeich LJ, Kwon H, Buonocore MH, Lammers CR, Reiss AL, Amaral DG (2004) The amygdala is enlarged in children but not adolescents with autism; the hippocampus is enlarged at all ages. J Neurosci 24(28):6392–6401PubMedCrossRef

Shaw P, Lerch J, Greenstein D, Sharp W, Clasen L, Evans A et al (2006) Longitudinal mapping of cortical thickness and clinical outcome in children and adolescents with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 63(5):540–549PubMedCrossRef

Shaw P, Eckstrand K, Sharp W, Blumenthal J, Lerch JP, Greenstein D et al (2007a) Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation. Proc Natl Acad Sci USA 104(49):19649–19654PubMedPubMedCentralCrossRef

Shaw P, Gornick M, Lerch J, Addington A, Seal J, Greenstein D et al (2007b) Polymorphisms of the dopamine D4 receptor, clinical outcome, and cortical structure in attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 64(8):921–931PubMedCrossRef

Shaw P, Lalonde F, Lepage C, Rabin C, Eckstrand K, Sharp W et al (2009) Development of cortical asymmetry in typically developing children and its disruption in attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 66(8):888–896PubMedPubMedCentralCrossRef

Shaw P, Gilliam M, Liverpool M, Weddle C, Malek M, Sharp W et al (2011) Cortical development in typically developing children with symptoms of hyperactivity and impulsivity: support for a dimensional view of attention deficit hyperactivity disorder. Am J Psychiatry n168(2):143–151CrossRef

Shaw M, Hodgkins P, Caci H, Young S, Kahle J, Woods AG, Arnold LE (2012a) A systematic review and analysis of long-term outcomes in attention deficit hyperactivity disorder: effects of treatment and non-treatment. BMC Med 10:99PubMedPubMedCentralCrossRef

Shaw P, Malek M, Watson B, Sharp W, Evans A, Greenstein D (2012b) Development of cortical surface area and gyrification in attention-deficit/hyperactivity disorder. Biol Psychiatry 72(3):191–197PubMedCrossRef

Shaw P, Malek M, Watson B, Greenstein D, de Rossi P, Sharp W (2013) Trajectories of cerebral cortical development in childhood and adolescence and adult attention-deficit/hyperactivity disorder. Biol Psychiatry 74(8):599–606PubMedCrossRef

Shaw P, Sudre G, Wharton A, Weingart D, Sharp W, Sarlls J (2015) White matter microstructure and the variable adult outcome of childhood attention deficit hyperactivity disorder. Neuropsychopharmacology. 40(3):746–754PubMedCrossRef

Sherman LE, Rudie JD, Pfeifer JH, Masten CL, McNealy K, Dapretto M (2014) Development of the default mode and central executive networks across early adolescence: a longitudinal study. Dev Cogn Neurosci 10:148–159PubMedPubMedCentralCrossRef

Simons A, Eyskens F, Glazemakers I, van West D (2016) Can psychiatric childhood disorders be due to inborn errors of metabolism? Eur Child Adolesc Psychiatry. doi:10.1007/s00787-016-0908-4

Sobel LJ, Bansal R, Maia TV, Sanchez J, Mazzone L, Durkin K et al (2010) Basal ganglia surface morphology and the effects of stimulant medications in youth with attention deficit hyperactivity disorder. Am J Psychiatry 167(8):977–986PubMedPubMedCentralCrossRef

Stanfield AC, McIntosh AM, Spencer MD, Philip R, Gaur S, Lawrie SM (2008) Towards a neuroanatomy of autism: a systematic review and meta-analysis of structural magnetic resonance imaging studies. Eur Psychiatry. 23(4):289–299PubMedCrossRef

Tan BW, Pooley JA, Speelman CP (2016) A meta-analytic review of the efficacy of physical exercise interventions on cognition in individuals with autism spectrum disorder and ADHD. J Autism Dev Disord 46(9):3126–3143PubMedCrossRef

Taylor MJ, Charman T, Ronald A (2015) Where are the strongest associations between autistic traits and traits of ADHD? evidence from a community-based twin study. Eur Child Adolesc Psychiatry 24(9):1129–1138PubMedPubMedCentralCrossRef

van der Meer JM, Oerlemans AM, van Steijn DJ, Lappenschaar MG, de Sonneville LM, Buitelaar JK, Rommelse NN (2012) Are autism spectrum disorder and attention-deficit/hyperactivity disorder different manifestations of one overarching disorder? Cognitive and symptom evidence from a clinical and population-based sample. J Am Acad Child Adolesc Psychiatry 51:1160–1172PubMedCrossRef

Via E, Radua J, Cardoner N, Happé F, Mataix-Cols D (2011) Meta-analysis of gray matter abnormalities in autism spectrum disorder: should Asperger disorder be subsumed under a broader umbrella of autistic spectrum disorder? Arch Gen Psychiatry 68(4):409–418PubMedCrossRef

Vijayakumar N, Whittle S, Dennison M, Yücel M, Simmons J, Allen NB (2014) Development of temperamental effortful control mediates the relationship between maturation of the prefrontal cortex and psychopathology during adolescence: a 4-year longitudinal study. Dev Cogn Neurosci 9:30–43PubMedCrossRef

Visser JC, Rommelse NN, Greven CU, Buitelaar JK (2016) Autism spectrum disorder and attention-deficit/hyperactivity disorder in early childhood: a review of unique and shared characteristics and developmental antecedents. Neurosci Biobehav Rev 65:229–263PubMedCrossRef

Wallace GL, Shaw P, Lee NR, Clasen LS, Raznahan A, Lenroot RK et al (2012) Distinct cortical correlates of autistic versus antisocial traits in a longitudinal sample of typically developing youth. J Neurosci 32(14):4856–4860PubMedPubMedCentralCrossRef

Wallace GL, Eisenberg IW, Robustelli B, Dankner N, Kenworthy L, Giedd JN, Martin A (2015) Longitudinal cortical development during adolescence and young adulthood in autism spectrum disorder: increased cortical thinning but comparable surface area changes. J Am Acad Child Adolesc Psychiatry 54(6):464–469PubMedPubMedCentralCrossRef

White T, Gottesman I (2012) Brain connectivity and gyrification as endophenotypes for schizophrenia: weight of the evidence. Curr Top Med Chem 12(21):2393–2403PubMedCrossRef

Whittle S, Simmons JG, Dennison M, Vijayakumar N, Schwartz O, Yap MB et al (2014) Positive parenting predicts the development of adolescent brain structure: a longitudinal study. Dev Cogn Neurosci 8:7–17PubMedCrossRef

Wolfers T, Buitelaar JK, Beckmann CF, Franke B, Marquand AF (2015) From estimating activation locality to predicting disorder: a review of pattern recognition for neuroimaging-based psychiatric diagnostics. Neurosci Biobehav Rev 57:328–349PubMedCrossRef

Zielinski BA, Prigge MB, Nielsen JA, Froehlich AL, Abildskov TJ, Anderson JS et al (2014) Longitudinal changes in cortical thickness in autism and typical development. Brain. 137:1799–1812PubMedPubMedCentralCrossRef

Title: Structural brain imaging correlates of ASD and ADHD across the lifespan: a hypothesis-generating review on developmental ASD–ADHD subtypes
Authors: Nanda Rommelse
Jan K. Buitelaar
Catharina A. Hartman
Publication date: 01-02-2017
Publisher: Springer Vienna
Published in: Journal of Neural Transmission / Issue 2/2017
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-016-1651-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Structural brain imaging correlates of ASD and ADHD across the lifespan: a hypothesis-generating review on developmental ASD–ADHD subtypes

Abstract

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 2/2017

Impaired heart rate variability in cervical dystonia is associated to depression

Anti-MAG autoantibodies are increased in Parkinson’s disease but not in atypical parkinsonism

Inhibitory effect of high-frequency greater occipital nerve electrical stimulation on trigeminovascular nociceptive processing in rats

Frontalis suspension surgery to treat patients with blepharospasm and eyelid opening apraxia: long-term results

Clustering of tau-immunoreactive pathology in chronic traumatic encephalopathy

D1 and D2 specific dopamine antagonist modulate the caudate nucleus neuronal responses to chronic methylphenidate exposure