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01-05-2012 | Basic Neurosciences, Genetics and Immunology - Original Article

On the origin of the triplet puzzle of homologies in receptor heteromers: toll-like receptor triplets in different types of receptors

Authors: Alexander O. Tarakanov, Kjell G. Fuxe, Dasiel O. Borroto-Escuela

Published in: Journal of Neural Transmission | Issue 5/2012

Abstract

Based on our theory, we have discovered main triplets of amino acid residues in the GABAB1 receptor and several other neural receptors, which seem to originate from toll-like receptors and appear also as homologies in receptor heteromers. The obtained results strengthen our hypothesis that these triplets may ‘guide-and-clasp’ receptor–receptor interactions.

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Title: On the origin of the triplet puzzle of homologies in receptor heteromers: toll-like receptor triplets in different types of receptors
Authors: Alexander O. Tarakanov
Kjell G. Fuxe
Dasiel O. Borroto-Escuela
Publication date: 01-05-2012
Publisher: Springer Vienna
Published in: Journal of Neural Transmission / Issue 5/2012
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-011-0734-2

At a glance: The STEP trials

Springer Medicine

On the origin of the triplet puzzle of homologies in receptor heteromers: toll-like receptor triplets in different types of receptors

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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