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01-09-2008 | Basic Neurosciences, Genetics and Immunology - Short Communication

The effects of 1 Hz rTMS over the hand area of M1 on movement kinematics of the ipsilateral hand

Authors: Manuel Dafotakis, Christian Grefkes, Ling Wang, Gereon R. Fink, Dennis A. Nowak

Published in: Journal of Neural Transmission | Issue 9/2008

Abstract

1 Hz rTMS applied over primary motor cortex (M1) reduces cortical excitability outlasting the stimulation period. Healthy right-handed subjects performed finger and hand tapping and a reach-to-grasp movement prior to (baseline) and after 1 Hz rTMS applied over (1) M1 of either the right or the left hemisphere, and (2) the vertex (control stimulation). 1 Hz rTMS applied over the left M1, but not over the vertex, improved movement kinematics of finger and hand tapping as well as grasping with the left hand. 1 Hz rTMS applied over the right M1, but not over the vertex, improved only the kinematics of hand tapping performed with the right hand. These data suggest that 1 Hz rTMS induced inhibition of ipsilateral M1 reduces transcallosal inhibition of contralateral M1 and thereby improves motor performance at the ipsilateral hand. The impact on motor performance of the ipsilateral hand is most pronounced after 1 Hz rTMS over the left M1.

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Title: The effects of 1 Hz rTMS over the hand area of M1 on movement kinematics of the ipsilateral hand
Authors: Manuel Dafotakis
Christian Grefkes
Ling Wang
Gereon R. Fink
Dennis A. Nowak
Publication date: 01-09-2008
Publisher: Springer Vienna
Published in: Journal of Neural Transmission / Issue 9/2008
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-008-0064-1

At a glance: The STEP trials

Springer Medicine

The effects of 1 Hz rTMS over the hand area of M1 on movement kinematics of the ipsilateral hand

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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