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Published in: Acta Neurochirurgica 12/2018

01-12-2018 | Case Report - Pituitaries

Growth hormone-secreting pituitary macroadenoma presenting concurrently with non-Hodgkin’s lymphoma and responding to doxorubicin treatment: case report and review of the literature

Authors: Gregory P. Lekovic, Asheesh Batra, Zachary R. Barnard, Eric P. Wilkinson, Richard Balena, Sheri Palejwala, Garni Barkhoudarian

Published in: Acta Neurochirurgica | Issue 12/2018

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Abstract

We present a case report of a patient who presented with nausea and vomiting, as well as acromegalic features. Following testing, a pituitary adenoma and mediastinal non-Hodgkin’s lymphoma were diagnosed. Following two cycles of R-CHOP chemotherapy, imaging showed significant decrease in size of the sellar tumor. Following resection of tumor, both frozen and permanent section revealed only necrotic material. Further research into the potential utility of doxorubicin for the treatment of recurrent or refractory pituitary adenomas may be warranted.
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Metadata
Title
Growth hormone-secreting pituitary macroadenoma presenting concurrently with non-Hodgkin’s lymphoma and responding to doxorubicin treatment: case report and review of the literature
Authors
Gregory P. Lekovic
Asheesh Batra
Zachary R. Barnard
Eric P. Wilkinson
Richard Balena
Sheri Palejwala
Garni Barkhoudarian
Publication date
01-12-2018
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 12/2018
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-018-3714-6

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