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Published in: Acta Neurochirurgica 1/2017

01-01-2017 | Case Report - Brain Tumors

Black hairy tongue after chemotherapy for malignant brain tumors

Authors: Yuki Yamagishi, Keisuke Maruyama, Keiichi Kobayashi, Satoshi Kume, Nobuyoshi Sasaki, Shigeomi Yokoya, Kuniaki Saito, Yoshiaki Shiokawa, Motoo Nagane

Published in: Acta Neurochirurgica | Issue 1/2017

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Abstract

Black hairy tongue (BHT) developed in five patients (2.6%) among 192 patients undergoing chemotherapy for malignant brain tumors. Three patients with a history of diabetes mellitus developed BHT within 10 days after the initiation of chemotherapy. The other two patients suffered more than 100 days after induction and lymphopenia of grade 3 or worse developed for more than 20 days, which was not observed in the three patients with diabetes. We found that BHT could develop after chemotherapy for malignant brain tumors. Patients with diabetes mellitus presented early after chemotherapy, while patients with longstanding severe lymphopenia presented in late phase.
Literature
1.
go back to reference Avcu N, Kanli A (2003) The prevalence of tongue lesions in 5150 Turkish dental outpatients. Oral Dis 9:188–195CrossRefPubMed Avcu N, Kanli A (2003) The prevalence of tongue lesions in 5150 Turkish dental outpatients. Oral Dis 9:188–195CrossRefPubMed
2.
go back to reference Chen SC, Sorrell TC, Chang CC, Paige EK, Bryant PA, Slavin MA (2014) Consensus guidelines for the treatment of yeast infections in the haematology, oncology and intensive care setting, 2014. Intern Med J 44:1315–1332CrossRefPubMed Chen SC, Sorrell TC, Chang CC, Paige EK, Bryant PA, Slavin MA (2014) Consensus guidelines for the treatment of yeast infections in the haematology, oncology and intensive care setting, 2014. Intern Med J 44:1315–1332CrossRefPubMed
3.
go back to reference Dall’oglio S, D’Amico A, Pioli F, Gabbani M, Pasini F, Passarin MG, Talacchi A, Turazzi S, Maluta S (2008) Dose-intensity temozolomide after concurrent chemoradiotherapy in operated high-grade gliomas. J Neurooncol 90:315–319CrossRefPubMed Dall’oglio S, D’Amico A, Pioli F, Gabbani M, Pasini F, Passarin MG, Talacchi A, Turazzi S, Maluta S (2008) Dose-intensity temozolomide after concurrent chemoradiotherapy in operated high-grade gliomas. J Neurooncol 90:315–319CrossRefPubMed
4.
go back to reference de Benedictis FM, Jorini M, Palumbo P (2012) Black tongue due to adrenocortical insufficiency. Arch Dis Child 97:1033CrossRefPubMed de Benedictis FM, Jorini M, Palumbo P (2012) Black tongue due to adrenocortical insufficiency. Arch Dis Child 97:1033CrossRefPubMed
5.
go back to reference Dimitrios S, Maria-Aikaterini P, Alexandre F, Nikolaos S (2012) Lingua villosa nigra. Intern Med 51:1453CrossRefPubMed Dimitrios S, Maria-Aikaterini P, Alexandre F, Nikolaos S (2012) Lingua villosa nigra. Intern Med 51:1453CrossRefPubMed
7.
go back to reference Harada Y, Gaafar H (1977) Black hairy tongue. A scanning electron microscopic study. J Laryngol Otol 91:91–96CrossRefPubMed Harada Y, Gaafar H (1977) Black hairy tongue. A scanning electron microscopic study. J Laryngol Otol 91:91–96CrossRefPubMed
8.
go back to reference Jeong JS, Lee JY, Kim MK, Yoon TY (2011) Black hairy tongue associated with erlotinib treatment in a patient with advanced lung cancer. Ann Dermatol 23:526–528CrossRefPubMedPubMedCentral Jeong JS, Lee JY, Kim MK, Yoon TY (2011) Black hairy tongue associated with erlotinib treatment in a patient with advanced lung cancer. Ann Dermatol 23:526–528CrossRefPubMedPubMedCentral
9.
go back to reference Jover-Diaz F, Cuadrado-Pastor JM, Talents-Bolos A, Martin-Gonzalez C (2010) Black tongue associated with linezolid. Am J Ther 17:e115–e117CrossRefPubMed Jover-Diaz F, Cuadrado-Pastor JM, Talents-Bolos A, Martin-Gonzalez C (2010) Black tongue associated with linezolid. Am J Ther 17:e115–e117CrossRefPubMed
10.
11.
go back to reference Kullaa-Mikkonen A, Mikkonen M, Kotilainen R (1982) Prevalence of different morphologic forms of the human tongue in young Finns. Oral Surg Oral Med Oral Pathol 53:152–156CrossRefPubMed Kullaa-Mikkonen A, Mikkonen M, Kotilainen R (1982) Prevalence of different morphologic forms of the human tongue in young Finns. Oral Surg Oral Med Oral Pathol 53:152–156CrossRefPubMed
12.
go back to reference Luo Y, Zou P, Li QB, You Y (2010) Black hairy tongue associated with allo peripheral blood hematopoietic stem cell transplantation. Chin Med J (Engl) 123:1807–1808 Luo Y, Zou P, Li QB, You Y (2010) Black hairy tongue associated with allo peripheral blood hematopoietic stem cell transplantation. Chin Med J (Engl) 123:1807–1808
13.
go back to reference Manabe M, Lim HW, Winzer M, Loomis CA (1999) Architectural organization of filiform papillae in normal and black hairy tongue epithelium: dissection of differentiation pathways in a complex human epithelium according to their patterns of keratin expression. Arch Dermatol 135:177–181CrossRefPubMed Manabe M, Lim HW, Winzer M, Loomis CA (1999) Architectural organization of filiform papillae in normal and black hairy tongue epithelium: dissection of differentiation pathways in a complex human epithelium according to their patterns of keratin expression. Arch Dermatol 135:177–181CrossRefPubMed
14.
go back to reference Mendez JS, Govindan A, Leong J, Gao F, Huang J, Campian JL (2016) Association between treatment-related lymphopenia and overall survival in elderly patients with newly diagnosed glioblastoma. J Neurooncol 127:329–335CrossRefPubMed Mendez JS, Govindan A, Leong J, Gao F, Huang J, Campian JL (2016) Association between treatment-related lymphopenia and overall survival in elderly patients with newly diagnosed glioblastoma. J Neurooncol 127:329–335CrossRefPubMed
15.
go back to reference Morris PG, Correa DD, Yahalom J, Raizer JJ, Schiff D, Grant B, Grimm S, Lai RK, Reiner AS, Panageas K, Karimi S, Curry R, Shah G, Abrey LE, DeAngelis LM, Omuro A (2013) Rituximab, methotrexate, procarbazine, and vincristine followed by consolidation reduced-dose whole-brain radiotherapy and cytarabine in newly diagnosed primary CNS lymphoma: final results and long-term outcome. J Clin Oncol 31:3971–3979CrossRefPubMed Morris PG, Correa DD, Yahalom J, Raizer JJ, Schiff D, Grant B, Grimm S, Lai RK, Reiner AS, Panageas K, Karimi S, Curry R, Shah G, Abrey LE, DeAngelis LM, Omuro A (2013) Rituximab, methotrexate, procarbazine, and vincristine followed by consolidation reduced-dose whole-brain radiotherapy and cytarabine in newly diagnosed primary CNS lymphoma: final results and long-term outcome. J Clin Oncol 31:3971–3979CrossRefPubMed
16.
go back to reference Motallebnejad M, Babaee N, Sakhdari S, Tavasoli M (2008) An epidemiologic study of tongue lesions in 1901 Iranian dental outpatients. J Contemp Dent Pract 9:73–80PubMed Motallebnejad M, Babaee N, Sakhdari S, Tavasoli M (2008) An epidemiologic study of tongue lesions in 1901 Iranian dental outpatients. J Contemp Dent Pract 9:73–80PubMed
18.
go back to reference Okita Y, Narita Y, Miyakita Y, Ohno M, Nagai S, Shibui S (2012) Management of cytomegalovirus infection in a patient with malignant glioma treated with temozolomide and steroids. Intern Med 51:2967–2971CrossRefPubMed Okita Y, Narita Y, Miyakita Y, Ohno M, Nagai S, Shibui S (2012) Management of cytomegalovirus infection in a patient with malignant glioma treated with temozolomide and steroids. Intern Med 51:2967–2971CrossRefPubMed
20.
go back to reference Phair J, Munoz A, Detels R, Kaslow R, Rinaldo C, Saah A (1990) The risk of Pneumocystis carinii pneumonia among men infected with human immunodeficiency virus type 1. Multicenter AIDS Cohort Study Group. N Engl J Med 322:161–165CrossRefPubMed Phair J, Munoz A, Detels R, Kaslow R, Rinaldo C, Saah A (1990) The risk of Pneumocystis carinii pneumonia among men infected with human immunodeficiency virus type 1. Multicenter AIDS Cohort Study Group. N Engl J Med 322:161–165CrossRefPubMed
21.
go back to reference Redman RS (1970) Prevalence of geographic tongue, fissured tongue, median rhomboid glossitis, and hairy tongue among 3,611 Minnesota schoolchildren. Oral Surg Oral Med Oral Pathol 30:390–395CrossRefPubMed Redman RS (1970) Prevalence of geographic tongue, fissured tongue, median rhomboid glossitis, and hairy tongue among 3,611 Minnesota schoolchildren. Oral Surg Oral Med Oral Pathol 30:390–395CrossRefPubMed
22.
go back to reference Scannapieco FA, Bush RB, Paju S (2003) Associations between periodontal disease and risk for nosocomial bacterial pneumonia and chronic obstructive pulmonary disease. A systematic review. Ann Periodontol 8:54–69CrossRefPubMed Scannapieco FA, Bush RB, Paju S (2003) Associations between periodontal disease and risk for nosocomial bacterial pneumonia and chronic obstructive pulmonary disease. A systematic review. Ann Periodontol 8:54–69CrossRefPubMed
24.
go back to reference Tamam L, Annagur BB (2006) Black hairy tongue associated with olanzapine treatment: a case report. Mt Sinai J Med 73:891–894PubMed Tamam L, Annagur BB (2006) Black hairy tongue associated with olanzapine treatment: a case report. Mt Sinai J Med 73:891–894PubMed
25.
26.
go back to reference Yu SK, Chalmers AJ (2007) Patients receiving standard-dose temozolomide therapy are at risk of Pneumocystis carinii pneumonia. Clin Oncol (R Coll Radiol) 19:631–632CrossRef Yu SK, Chalmers AJ (2007) Patients receiving standard-dose temozolomide therapy are at risk of Pneumocystis carinii pneumonia. Clin Oncol (R Coll Radiol) 19:631–632CrossRef
Metadata
Title
Black hairy tongue after chemotherapy for malignant brain tumors
Authors
Yuki Yamagishi
Keisuke Maruyama
Keiichi Kobayashi
Satoshi Kume
Nobuyoshi Sasaki
Shigeomi Yokoya
Kuniaki Saito
Yoshiaki Shiokawa
Motoo Nagane
Publication date
01-01-2017
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 1/2017
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-016-3036-5

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